Breast cancer cell lines: Friend or foe?

Sarah E. Burdall; Andrew M. Hanby; Mark R.J. Lansdown; Valerie Speirs

doi:10.1186/bcr577

Breast cancer cell lines: Friend or foe?

Sarah E. Burdall, Andrew M. Hanby, Mark R.J. Lansdown, Valerie Speirs^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

228 Citations (Scopus)

Abstract

The majority of breast cancer research is conducted using established breast cancer cell lines as in vitro models. An alternative is to use cultures established from primary breast tumours. Here, we discuss the pros and cons of using both of these models in translational breast cancer research.

Original language	English
Pages (from-to)	89-95
Number of pages	7
Journal	Breast Cancer Research
Volume	5
Issue number	2
DOIs	https://doi.org/10.1186/bcr577
Publication status	Published - 2003
Externally published	Yes

Keywords

Cell culture
In vitro models
Mammary gland

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1186/bcr577

Cite this

@article{df1c53b8dd0a48ff9e16fb1e379c9542,

title = "Breast cancer cell lines: Friend or foe?",

abstract = "The majority of breast cancer research is conducted using established breast cancer cell lines as in vitro models. An alternative is to use cultures established from primary breast tumours. Here, we discuss the pros and cons of using both of these models in translational breast cancer research.",

keywords = "Cell culture, In vitro models, Mammary gland",

author = "Burdall, {Sarah E.} and Hanby, {Andrew M.} and Lansdown, {Mark R.J.} and Valerie Speirs",

year = "2003",

doi = "10.1186/bcr577",

language = "English",

volume = "5",

pages = "89--95",

journal = "Breast Cancer Research",

issn = "1465-5411",

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}

TY - JOUR

T1 - Breast cancer cell lines

T2 - Friend or foe?

AU - Burdall, Sarah E.

AU - Hanby, Andrew M.

AU - Lansdown, Mark R.J.

AU - Speirs, Valerie

PY - 2003

Y1 - 2003

N2 - The majority of breast cancer research is conducted using established breast cancer cell lines as in vitro models. An alternative is to use cultures established from primary breast tumours. Here, we discuss the pros and cons of using both of these models in translational breast cancer research.

AB - The majority of breast cancer research is conducted using established breast cancer cell lines as in vitro models. An alternative is to use cultures established from primary breast tumours. Here, we discuss the pros and cons of using both of these models in translational breast cancer research.

KW - Cell culture

KW - In vitro models

KW - Mammary gland

UR - http://www.scopus.com/inward/record.url?scp=0345700343&partnerID=8YFLogxK

U2 - 10.1186/bcr577

DO - 10.1186/bcr577

M3 - Review article

C2 - 12631387

AN - SCOPUS:0345700343

SN - 1465-5411

VL - 5

SP - 89

EP - 95

JO - Breast Cancer Research

JF - Breast Cancer Research

IS - 2

ER -

Breast cancer cell lines: Friend or foe?

Abstract

Keywords

UN SDGs

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