Chemical genetics: receptor-ligand pairs for rapid manipulation of neuronal activity

Peer Wulff, Benjamin R Arenkiel

Research output: Contribution to journalArticle

23 Citations (Scopus)
6 Downloads (Pure)

Abstract

Toward the functional dissection of neuronal circuits, a number of new genetic tools have been developed that enable rapid and reversible manipulation of genetically defined neuronal subtypes in intact mammalian brain circuits. Alongside the breakthrough technology of optogenetics, receptor-ligand pairs provide complementary approaches to modulate neuronal activity using chemical genetics.
Original languageEnglish
Pages (from-to)54-60
Number of pages7
JournalCurrent Opinion in Neurobiology
Volume22
Issue number1
Early online date24 Nov 2011
DOIs
Publication statusPublished - Feb 2012

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