Combining biochemical network motifs within an ARN-agent control system

Claire E. Gerrard, John McCall, Christopher Macleod, George M. Coghill

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The Artificial Reaction Network (ARN) is an Artificial Chemistry representation inspired by cell signaling networks. The ARN has previously been applied to the simulation of the chemotaxis pathway of Escherichia coli and to the control of limbed robots. In this paper we discuss the design of an ARN control system composed of a combination of network motifs found in actual biochemical networks. Using this control system we create multiple cell-like autonomous agents capable of coordinating all aspects of their behavior, recognizing environmental patterns and communicating with other agent's stigmergically. The agents are applied to simulate two phases of the life cycle of Dictyostelium discoideum: vegetative and aggregation phase including the transition. The results of the simulation show that the ARN is well suited for construction of biochemical regulatory networks. Furthermore, it is a powerful tool for modeling multi agent systems such as a population of amoebae or bacterial colony.

Original languageEnglish
Title of host publication2013 13th UK Workshop on Computational Intelligence (UKCI)
EditorsYaochu Jin, Spencer Angus Thomas
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Pages8-15
Number of pages8
ISBN (Electronic)9781479915682
DOIs
Publication statusPublished - 2013
Event2013 13th UK Workshop on Computational Intelligence, UKCI 2013 - Guildford, Surrey, United Kingdom
Duration: 9 Sep 201311 Sep 2013

Conference

Conference2013 13th UK Workshop on Computational Intelligence, UKCI 2013
CountryUnited Kingdom
CityGuildford, Surrey
Period9/09/1311/09/13

Fingerprint

Cell signaling
Control systems
Autonomous agents
Multi agent systems
Escherichia coli
Life cycle
Agglomeration
Robots

Keywords

  • Artificial Chemistry
  • Artificial Reaction Networks
  • Swarm Agents

ASJC Scopus subject areas

  • Artificial Intelligence
  • Computational Theory and Mathematics

Cite this

Gerrard, C. E., McCall, J., Macleod, C., & Coghill, G. M. (2013). Combining biochemical network motifs within an ARN-agent control system. In Y. Jin, & S. A. Thomas (Eds.), 2013 13th UK Workshop on Computational Intelligence (UKCI) (pp. 8-15). [6651281] Institute of Electrical and Electronics Engineers (IEEE). https://doi.org/10.1109/UKCI.2013.6651281

Combining biochemical network motifs within an ARN-agent control system. / Gerrard, Claire E.; McCall, John; Macleod, Christopher; Coghill, George M.

2013 13th UK Workshop on Computational Intelligence (UKCI). ed. / Yaochu Jin; Spencer Angus Thomas. Institute of Electrical and Electronics Engineers (IEEE), 2013. p. 8-15 6651281.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gerrard, CE, McCall, J, Macleod, C & Coghill, GM 2013, Combining biochemical network motifs within an ARN-agent control system. in Y Jin & SA Thomas (eds), 2013 13th UK Workshop on Computational Intelligence (UKCI)., 6651281, Institute of Electrical and Electronics Engineers (IEEE), pp. 8-15, 2013 13th UK Workshop on Computational Intelligence, UKCI 2013, Guildford, Surrey, United Kingdom, 9/09/13. https://doi.org/10.1109/UKCI.2013.6651281
Gerrard CE, McCall J, Macleod C, Coghill GM. Combining biochemical network motifs within an ARN-agent control system. In Jin Y, Thomas SA, editors, 2013 13th UK Workshop on Computational Intelligence (UKCI). Institute of Electrical and Electronics Engineers (IEEE). 2013. p. 8-15. 6651281 https://doi.org/10.1109/UKCI.2013.6651281
Gerrard, Claire E. ; McCall, John ; Macleod, Christopher ; Coghill, George M. / Combining biochemical network motifs within an ARN-agent control system. 2013 13th UK Workshop on Computational Intelligence (UKCI). editor / Yaochu Jin ; Spencer Angus Thomas. Institute of Electrical and Electronics Engineers (IEEE), 2013. pp. 8-15
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