Contribution of diet to the composition of the human gut microbiota

Daniela Graf, Raffaella Di Cagno, Frida Fåk, Harry J Flint, Margareta Nyman, Maria Saarela, Bernhard Watzl

Research output: Contribution to journalArticle

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Abstract

In the human gut, millions of bacteria contribute to the microbiota, whose composition is specific for every individual. Although we are just at the very beginning of understanding the microbiota concept, we already know that the composition of the microbiota has a profound impact on human health. A key factor in determining gut microbiota composition is diet. Preliminary evidence suggests that dietary patterns are associated with distinct combinations of bacteria in the intestine, also called enterotypes. Western diets result in significantly different microbiota compositions than traditional diets. It is currently unknown which food constituents specifically promote growth and functionality of beneficial bacteria in the intestine. The aim of this review is to summarize the recently published evidence from human in vivo studies on the gut microbiota-modulating effects of diet. It includes sections on dietary patterns (e.g. Western diet), whole foods, food constituents, as wells as food-associated microbes and their influence on the composition of human gut microbiota. The conclusions highlight the problems faced by scientists in this fast-developing field of research, and the need for high-quality, large-scale human dietary intervention studies.

Original languageEnglish
Article number26164
Number of pages11
JournalMicrobial Ecology in Health and Disease
Volume26
Early online date4 Feb 2015
DOIs
Publication statusPublished - 2015

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Microbiota
Diet
Food
Bacteria
Intestines
Gastrointestinal Microbiome
Health
Growth
Research
Western Diet

Keywords

  • human gut microbiota
  • dietary patterns
  • food constituents
  • diet

Cite this

Contribution of diet to the composition of the human gut microbiota. / Graf, Daniela; Di Cagno, Raffaella; Fåk, Frida; Flint, Harry J; Nyman, Margareta; Saarela, Maria; Watzl, Bernhard.

In: Microbial Ecology in Health and Disease, Vol. 26, 26164, 2015.

Research output: Contribution to journalArticle

Graf, Daniela ; Di Cagno, Raffaella ; Fåk, Frida ; Flint, Harry J ; Nyman, Margareta ; Saarela, Maria ; Watzl, Bernhard. / Contribution of diet to the composition of the human gut microbiota. In: Microbial Ecology in Health and Disease. 2015 ; Vol. 26.
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