Detection of halogenated tryramine and tyrosine derivatives in extracts of Algoa Bay ascidians

C. L. Bromley, A. Raab, D. Beukes, J. Feldmann, M. Jaspars, M. T. Davies-Coleman

Research output: Contribution to journalAbstract

Abstract

he crude organic extracts of ascidian species collected from Algoa Bay, South Africa were analysed using liquid chromatography with parallel inductively coupled plasma mass spectrometry/electrospray mass spectrometry (LC-ICP-MS/ESI-MS). The data obtained was used to detect a number of brominated and iodinated tyramine and tyrosine derivatives with in the ascidian extracts establishing this method as a powerful tool for the dereplication of halogenated metabolites in complex mixtures.
Original languageEnglish
Pages (from-to)914
Number of pages1
JournalPlanta Medica
Volume81
Issue number11
DOIs
Publication statusPublished - Jul 2015
EventAnnual Meeting of the American-Society-of-Pharmacognosy - , Colombia
Duration: 25 Jul 201529 Jul 2015

Keywords

  • Halogenated tryamine
  • Tyrosine derivatives
  • Algoa Bay
  • Asicdian species

Cite this

Detection of halogenated tryramine and tyrosine derivatives in extracts of Algoa Bay ascidians. / Bromley, C. L.; Raab, A.; Beukes, D.; Feldmann, J.; Jaspars, M.; Davies-Coleman, M. T.

In: Planta Medica, Vol. 81, No. 11, 07.2015, p. 914.

Research output: Contribution to journalAbstract

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T1 - Detection of halogenated tryramine and tyrosine derivatives in extracts of Algoa Bay ascidians

AU - Bromley, C. L.

AU - Raab, A.

AU - Beukes, D.

AU - Feldmann, J.

AU - Jaspars, M.

AU - Davies-Coleman, M. T.

PY - 2015/7

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AB - he crude organic extracts of ascidian species collected from Algoa Bay, South Africa were analysed using liquid chromatography with parallel inductively coupled plasma mass spectrometry/electrospray mass spectrometry (LC-ICP-MS/ESI-MS). The data obtained was used to detect a number of brominated and iodinated tyramine and tyrosine derivatives with in the ascidian extracts establishing this method as a powerful tool for the dereplication of halogenated metabolites in complex mixtures.

KW - Halogenated tryamine

KW - Tyrosine derivatives

KW - Algoa Bay

KW - Asicdian species

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DO - 10.1055/s-0035-1556363

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