Determinants of successful lifestyle change during a 6-month preconception lifestyle intervention in women with obesity and infertility

LIFEstyle study group

doi:10.1007/s00394-018-1798-7

Determinants of successful lifestyle change during a 6-month preconception lifestyle intervention in women with obesity and infertility

LIFEstyle study group

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Purpose: To identify demographic, (bio)physical, behavioral, and psychological determinants of successful lifestyle change and program completion by performing a secondary analysis of the intervention arm of a randomized-controlled trial, investigating a preconception lifestyle intervention. Methods: The 6-month lifestyle intervention consisted of dietary counseling, physical activity, and behavioral modification, and was aimed at 5–10% weight loss. We operationalized successful lifestyle change as successful weight loss (≥ 5% weight/BMI ≤ 29 kg/m²), weight loss in kilograms, a reduction in energy intake, and an increase in physical activity during the intervention program. We performed logistic and mixed-effect regression analyses to identify baseline factors that were associated with successful change or program completion. Results: Women with higher external eating behavior scores had higher odds of successful weight loss (OR 1.10, 95% CI 1.05–1.16). Women with the previous dietetic support lost 0.94 kg less during the intervention period (95% CI 0.01–1.87 kg). Women with higher self-efficacy reduced energy intake more than women with lower self-efficacy (p < 0.01). Women with an older partner had an increased energy intake (6 kcal/year older, 95% CI 3–13). A high stage of change towards physical activity was associated with a higher number of daily steps (p = 0.03). A high stage of change towards weight loss was associated with completion of the intervention (p = 0.04). Conclusions: Determinants of lifestyle change and program completion were: higher external eating behavior, not having received previous dietetic support, high stage of change. This knowledge can be used to identify women likely to benefit from lifestyle interventions and develop new interventions for women requiring alternative support. Trial registration: The LIFEstyle study was registered at the Dutch trial registry (NTR 1530; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=1530).

Original language	English
Pages (from-to)	2463-2475
Number of pages	13
Journal	European Journal of Nutrition
Volume	58
Issue number	6
Early online date	3 Aug 2018
DOIs	https://doi.org/10.1007/s00394-018-1798-7
Publication status	Published - 1 Sept 2019

Bibliographical note

Funding The LIFEstyle study was supported by a grant from ZonMw
(Prevention program—Health Care Efficiency Research; Project number 50-50110-96-518). This work was funded by the Dutch Heart
Foundation (2013T085) and the European Commission (Horizon2020
project 633595 DynaHealth). Neither ZonMw nor the Dutch Heart
Foundation nor the European Commission had a role in data collection,
analysis, interpretation of data, or writing the report.

cknowledgements We would like to thank the women who participated in this study. We thank all participating hospitals and their
staff for their contribution to this study, and the LIFEstyle coaches
and research nurses, research midwives, and office members of the
Dutch Consortium 2.0 (http://www.studies-obsgyn.nl) for their hard
work and dedication. We would like to acknowledge Mrs. A. Bolster
(University Medical Center Groningen) as senior trainer of the intervention coaches

Data Availability Statement

No data availability statement

Keywords

Determinants
Lifestyle intervention
Obesity
Preconception

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

@article{6480a9de142b44629afac04003dd06b1,

title = "Determinants of successful lifestyle change during a 6-month preconception lifestyle intervention in women with obesity and infertility",

abstract = "Purpose: To identify demographic, (bio)physical, behavioral, and psychological determinants of successful lifestyle change and program completion by performing a secondary analysis of the intervention arm of a randomized-controlled trial, investigating a preconception lifestyle intervention. Methods: The 6-month lifestyle intervention consisted of dietary counseling, physical activity, and behavioral modification, and was aimed at 5–10% weight loss. We operationalized successful lifestyle change as successful weight loss (≥ 5% weight/BMI ≤ 29 kg/m2), weight loss in kilograms, a reduction in energy intake, and an increase in physical activity during the intervention program. We performed logistic and mixed-effect regression analyses to identify baseline factors that were associated with successful change or program completion. Results: Women with higher external eating behavior scores had higher odds of successful weight loss (OR 1.10, 95% CI 1.05–1.16). Women with the previous dietetic support lost 0.94 kg less during the intervention period (95% CI 0.01–1.87 kg). Women with higher self-efficacy reduced energy intake more than women with lower self-efficacy (p < 0.01). Women with an older partner had an increased energy intake (6 kcal/year older, 95% CI 3–13). A high stage of change towards physical activity was associated with a higher number of daily steps (p = 0.03). A high stage of change towards weight loss was associated with completion of the intervention (p = 0.04). Conclusions: Determinants of lifestyle change and program completion were: higher external eating behavior, not having received previous dietetic support, high stage of change. This knowledge can be used to identify women likely to benefit from lifestyle interventions and develop new interventions for women requiring alternative support. Trial registration: The LIFEstyle study was registered at the Dutch trial registry (NTR 1530; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=1530).",

keywords = "Determinants, Lifestyle intervention, Obesity, Preconception",

author = "Karsten, {Matty D.A.} and {van Oers}, {Anne M.} and Henk Groen and Mutsaerts, {Meike A.Q.} and {van Poppel}, {Mireille N.M.} and Anouk Geelen and {van de Beek}, Cornelieke and Painter, {Rebecca C.} and Mol, {Ben W.J.} and Roseboom, {Tessa J.} and Annemieke Hoek and Burggraaff, {J. M.} and Kuchenbecker, {W. K.H.} and Perquin, {D. A.M.} and Koks, {C. A.M.} and {van Golde}, R. and Kaaijk, {E. M.} and Schierbeek, {J. M.} and Oosterhuis, {G. J.E.} and Broekmans, {F. J.} and Vogel, {N. E.A.} and Lambalk, {C. B.} and {van der Veen}, F. and Klijn, {N. F.} and Mercelina, {P. E.A.M.} and {van Kasteren}, {Y. M.} and Nap, {A. W.} and Mulder, {R. J.A.B.} and Gondrie, {E. T.C.M.} and {de Bruin}, {J. P.} and {LIFEstyle study group}",

note = "Funding The LIFEstyle study was supported by a grant from ZonMw (Prevention program—Health Care Efficiency Research; Project number 50-50110-96-518). This work was funded by the Dutch Heart Foundation (2013T085) and the European Commission (Horizon2020 project 633595 DynaHealth). Neither ZonMw nor the Dutch Heart Foundation nor the European Commission had a role in data collection, analysis, interpretation of data, or writing the report. cknowledgements We would like to thank the women who participated in this study. We thank all participating hospitals and their staff for their contribution to this study, and the LIFEstyle coaches and research nurses, research midwives, and office members of the Dutch Consortium 2.0 (http://www.studies-obsgyn.nl) for their hard work and dedication. We would like to acknowledge Mrs. A. Bolster (University Medical Center Groningen) as senior trainer of the intervention coaches",

year = "2019",

month = sep,

day = "1",

doi = "10.1007/s00394-018-1798-7",

language = "English",

volume = "58",

pages = "2463--2475",

journal = "European Journal of Nutrition",

issn = "1436-6207",

publisher = "D. Steinkopff-Verlag",

number = "6",

}

TY - JOUR

T1 - Determinants of successful lifestyle change during a 6-month preconception lifestyle intervention in women with obesity and infertility

AU - Karsten, Matty D.A.

AU - van Oers, Anne M.

AU - Groen, Henk

AU - Mutsaerts, Meike A.Q.

AU - van Poppel, Mireille N.M.

AU - Geelen, Anouk

AU - van de Beek, Cornelieke

AU - Painter, Rebecca C.

AU - Mol, Ben W.J.

AU - Roseboom, Tessa J.

AU - Hoek, Annemieke

AU - Burggraaff, J. M.

AU - Kuchenbecker, W. K.H.

AU - Perquin, D. A.M.

AU - Koks, C. A.M.

AU - van Golde, R.

AU - Kaaijk, E. M.

AU - Schierbeek, J. M.

AU - Oosterhuis, G. J.E.

AU - Broekmans, F. J.

AU - Vogel, N. E.A.

AU - Lambalk, C. B.

AU - van der Veen, F.

AU - Klijn, N. F.

AU - Mercelina, P. E.A.M.

AU - van Kasteren, Y. M.

AU - Nap, A. W.

AU - Mulder, R. J.A.B.

AU - Gondrie, E. T.C.M.

AU - de Bruin, J. P.

AU - LIFEstyle study group

N1 - Funding The LIFEstyle study was supported by a grant from ZonMw (Prevention program—Health Care Efficiency Research; Project number 50-50110-96-518). This work was funded by the Dutch Heart Foundation (2013T085) and the European Commission (Horizon2020 project 633595 DynaHealth). Neither ZonMw nor the Dutch Heart Foundation nor the European Commission had a role in data collection, analysis, interpretation of data, or writing the report. cknowledgements We would like to thank the women who participated in this study. We thank all participating hospitals and their staff for their contribution to this study, and the LIFEstyle coaches and research nurses, research midwives, and office members of the Dutch Consortium 2.0 (http://www.studies-obsgyn.nl) for their hard work and dedication. We would like to acknowledge Mrs. A. Bolster (University Medical Center Groningen) as senior trainer of the intervention coaches

PY - 2019/9/1

Y1 - 2019/9/1

N2 - Purpose: To identify demographic, (bio)physical, behavioral, and psychological determinants of successful lifestyle change and program completion by performing a secondary analysis of the intervention arm of a randomized-controlled trial, investigating a preconception lifestyle intervention. Methods: The 6-month lifestyle intervention consisted of dietary counseling, physical activity, and behavioral modification, and was aimed at 5–10% weight loss. We operationalized successful lifestyle change as successful weight loss (≥ 5% weight/BMI ≤ 29 kg/m2), weight loss in kilograms, a reduction in energy intake, and an increase in physical activity during the intervention program. We performed logistic and mixed-effect regression analyses to identify baseline factors that were associated with successful change or program completion. Results: Women with higher external eating behavior scores had higher odds of successful weight loss (OR 1.10, 95% CI 1.05–1.16). Women with the previous dietetic support lost 0.94 kg less during the intervention period (95% CI 0.01–1.87 kg). Women with higher self-efficacy reduced energy intake more than women with lower self-efficacy (p < 0.01). Women with an older partner had an increased energy intake (6 kcal/year older, 95% CI 3–13). A high stage of change towards physical activity was associated with a higher number of daily steps (p = 0.03). A high stage of change towards weight loss was associated with completion of the intervention (p = 0.04). Conclusions: Determinants of lifestyle change and program completion were: higher external eating behavior, not having received previous dietetic support, high stage of change. This knowledge can be used to identify women likely to benefit from lifestyle interventions and develop new interventions for women requiring alternative support. Trial registration: The LIFEstyle study was registered at the Dutch trial registry (NTR 1530; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=1530).

AB - Purpose: To identify demographic, (bio)physical, behavioral, and psychological determinants of successful lifestyle change and program completion by performing a secondary analysis of the intervention arm of a randomized-controlled trial, investigating a preconception lifestyle intervention. Methods: The 6-month lifestyle intervention consisted of dietary counseling, physical activity, and behavioral modification, and was aimed at 5–10% weight loss. We operationalized successful lifestyle change as successful weight loss (≥ 5% weight/BMI ≤ 29 kg/m2), weight loss in kilograms, a reduction in energy intake, and an increase in physical activity during the intervention program. We performed logistic and mixed-effect regression analyses to identify baseline factors that were associated with successful change or program completion. Results: Women with higher external eating behavior scores had higher odds of successful weight loss (OR 1.10, 95% CI 1.05–1.16). Women with the previous dietetic support lost 0.94 kg less during the intervention period (95% CI 0.01–1.87 kg). Women with higher self-efficacy reduced energy intake more than women with lower self-efficacy (p < 0.01). Women with an older partner had an increased energy intake (6 kcal/year older, 95% CI 3–13). A high stage of change towards physical activity was associated with a higher number of daily steps (p = 0.03). A high stage of change towards weight loss was associated with completion of the intervention (p = 0.04). Conclusions: Determinants of lifestyle change and program completion were: higher external eating behavior, not having received previous dietetic support, high stage of change. This knowledge can be used to identify women likely to benefit from lifestyle interventions and develop new interventions for women requiring alternative support. Trial registration: The LIFEstyle study was registered at the Dutch trial registry (NTR 1530; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=1530).

KW - Determinants

KW - Lifestyle intervention

KW - Obesity

KW - Preconception

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U2 - 10.1007/s00394-018-1798-7

DO - 10.1007/s00394-018-1798-7

M3 - Article

C2 - 30076459

AN - SCOPUS:85051515434

SN - 1436-6207

VL - 58

SP - 2463

EP - 2475

JO - European Journal of Nutrition

JF - European Journal of Nutrition

IS - 6

ER -