Effect of temperature on skeletal muscle energy turnover during dynamic knee-extensor exercise in humans

R. A. Ferguson, P. Krustrup, M. Kjær, M. Mohr, D. Ball, J. Bangsbo

Research output: Contribution to journalArticle

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Abstract

The present study examined the effect of elevated temperature on muscle energy turnover during dynamic exercise. Nine male subjects performed 10 min of dynamic knee-extensor exercise at an intensity of 43 W (SD 10) and a frequency of 60 contractions per minute. Exercise was performed under normal (C) and elevated muscle temperature (HT) through passive heating. Thigh oxygen uptake (V̇;O2) was determined from measurements of thigh blood flow and femoral arterial-venous differences for oxygen content. Anaerobic energy turnover was estimated from measurements of lactate release as well as muscle lactate accumulation and phosphocreatine utilization based on analysis of muscle biopsies obtained before and after each exercise. At the start of exercise, muscle temperature was 34.5°C (SD 1.7) in C compared with 37.2°C (SD 0.5) during HT (P < 0.05). Thigh V̇O2 after 3 min was 0.52 l/min (SD 0.11) in C and 0.63 l/min (SD 0.13) in HT, and at the end of exercise it was 0.60 l/min (SD 0.14) and 0.61 l/min (SD 0.10) in C and HT, respectively (not significant). Total lactate release was the same between the two temperature conditions, as was muscle lactate accumulation and PCr utilization. Total ATP production (aerobic + anaerobic) was the same between each temperature condition [505.0 mmol/kg (SD 107.2) vs. 527.1 mmol/kg (SD 117.6); C and HT, respectively]. In conclusion, within the range of temperatures studied, passively increasing muscle temperature before exercise has no effect on muscle energy turnover during dynamic exercise.

Original languageEnglish
Pages (from-to)47-52
Number of pages6
JournalJournal of Applied Physiology
Volume101
Issue number1
DOIs
Publication statusPublished - 2006

Fingerprint

Knee
Skeletal Muscle
Muscles
Temperature
Thigh
Lactic Acid
Oxygen
Phosphocreatine
Heating
Adenosine Triphosphate
Biopsy

Keywords

  • ATP turnover
  • Energy production
  • Mechanical efficiency

ASJC Scopus subject areas

  • Endocrinology
  • Physiology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Effect of temperature on skeletal muscle energy turnover during dynamic knee-extensor exercise in humans. / Ferguson, R. A.; Krustrup, P.; Kjær, M.; Mohr, M.; Ball, D.; Bangsbo, J.

In: Journal of Applied Physiology, Vol. 101, No. 1, 2006, p. 47-52.

Research output: Contribution to journalArticle

Ferguson, R. A. ; Krustrup, P. ; Kjær, M. ; Mohr, M. ; Ball, D. ; Bangsbo, J. / Effect of temperature on skeletal muscle energy turnover during dynamic knee-extensor exercise in humans. In: Journal of Applied Physiology. 2006 ; Vol. 101, No. 1. pp. 47-52.
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