Exhaled nitric oxide is reduced in infants with rhinorrhoea

P. J. Franklin, Stephen William Turner, G. L. Hall, A. Moeller, S. M. Stick

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

In infants, the effect of colds and other respiratory tract infections (RTI) on exhaled nitric oxide (FENO) is not clear In this study, we measured FENO in 24 infants (14 boys) who presented with rhinorrhea, with or without Cough but not wheeze. Twelve of these infants had a history of recurrent wheeze. Levels were compared with a group of 23 healthy infants (13 boys). Further, 8 infants (5 with a history of recurrent wheeze) with rhinorrhea were tested after symptoms had resolved. Infants with rhinorrhea had significantly lower FENO than the healthy infants (11.9vs. 23.8 ppb, respectively, P< 0.0007). Levels increased from 7.5 ppb to 34.1 ppb in the 8 infants tested with and without symptoms (P = 0.0002). Infants with rhinorrhea have reduced FENO, irrespective of their respiratory history.

Original languageEnglish
Pages (from-to)117-119
Number of pages2
JournalPediatric Pulmonology
Volume39
DOIs
Publication statusPublished - 2005

Keywords

  • exhaled nitric oxide
  • infants
  • rhinorrhea
  • SINGLE-BREATH
  • THERAPY

Cite this

Exhaled nitric oxide is reduced in infants with rhinorrhoea. / Franklin, P. J.; Turner, Stephen William; Hall, G. L.; Moeller, A.; Stick, S. M.

In: Pediatric Pulmonology, Vol. 39, 2005, p. 117-119.

Research output: Contribution to journalArticle

Franklin, P. J. ; Turner, Stephen William ; Hall, G. L. ; Moeller, A. ; Stick, S. M. / Exhaled nitric oxide is reduced in infants with rhinorrhoea. In: Pediatric Pulmonology. 2005 ; Vol. 39. pp. 117-119.
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