Exhaled nitric oxide is reduced in infants with rhinorrhoea

P. J. Franklin; Stephen William Turner; G. L. Hall; A. Moeller; S. M. Stick

doi:10.1002/ppul.20149

Exhaled nitric oxide is reduced in infants with rhinorrhoea

P. J. Franklin, Stephen William Turner, G. L. Hall, A. Moeller, S. M. Stick

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

In infants, the effect of colds and other respiratory tract infections (RTI) on exhaled nitric oxide (FENO) is not clear In this study, we measured FENO in 24 infants (14 boys) who presented with rhinorrhea, with or without Cough but not wheeze. Twelve of these infants had a history of recurrent wheeze. Levels were compared with a group of 23 healthy infants (13 boys). Further, 8 infants (5 with a history of recurrent wheeze) with rhinorrhea were tested after symptoms had resolved. Infants with rhinorrhea had significantly lower FENO than the healthy infants (11.9vs. 23.8 ppb, respectively, P< 0.0007). Levels increased from 7.5 ppb to 34.1 ppb in the 8 infants tested with and without symptoms (P = 0.0002). Infants with rhinorrhea have reduced FENO, irrespective of their respiratory history.

Original language	English
Pages (from-to)	117-119
Number of pages	2
Journal	Pediatric Pulmonology
Volume	39
DOIs	https://doi.org/10.1002/ppul.20149
Publication status	Published - 2005

Keywords

exhaled nitric oxide
infants
rhinorrhea
SINGLE-BREATH
THERAPY

Access to Document

10.1002/ppul.20149

Cite this

@article{f2b2395c40914c0587eca26b83ac1955,

title = "Exhaled nitric oxide is reduced in infants with rhinorrhoea",

abstract = "In infants, the effect of colds and other respiratory tract infections (RTI) on exhaled nitric oxide (FENO) is not clear In this study, we measured FENO in 24 infants (14 boys) who presented with rhinorrhea, with or without Cough but not wheeze. Twelve of these infants had a history of recurrent wheeze. Levels were compared with a group of 23 healthy infants (13 boys). Further, 8 infants (5 with a history of recurrent wheeze) with rhinorrhea were tested after symptoms had resolved. Infants with rhinorrhea had significantly lower FENO than the healthy infants (11.9vs. 23.8 ppb, respectively, P< 0.0007). Levels increased from 7.5 ppb to 34.1 ppb in the 8 infants tested with and without symptoms (P = 0.0002). Infants with rhinorrhea have reduced FENO, irrespective of their respiratory history.",

keywords = "exhaled nitric oxide, infants, rhinorrhea, SINGLE-BREATH, THERAPY",

author = "Franklin, {P. J.} and Turner, {Stephen William} and Hall, {G. L.} and A. Moeller and Stick, {S. M.}",

year = "2005",

doi = "10.1002/ppul.20149",

language = "English",

volume = "39",

pages = "117--119",

journal = "Pediatric Pulmonology",

issn = "8755-6863",

publisher = "John Wiley & Sons, Ltd",

}

TY - JOUR

T1 - Exhaled nitric oxide is reduced in infants with rhinorrhoea

AU - Franklin, P. J.

AU - Turner, Stephen William

AU - Hall, G. L.

AU - Moeller, A.

AU - Stick, S. M.

PY - 2005

Y1 - 2005

N2 - In infants, the effect of colds and other respiratory tract infections (RTI) on exhaled nitric oxide (FENO) is not clear In this study, we measured FENO in 24 infants (14 boys) who presented with rhinorrhea, with or without Cough but not wheeze. Twelve of these infants had a history of recurrent wheeze. Levels were compared with a group of 23 healthy infants (13 boys). Further, 8 infants (5 with a history of recurrent wheeze) with rhinorrhea were tested after symptoms had resolved. Infants with rhinorrhea had significantly lower FENO than the healthy infants (11.9vs. 23.8 ppb, respectively, P< 0.0007). Levels increased from 7.5 ppb to 34.1 ppb in the 8 infants tested with and without symptoms (P = 0.0002). Infants with rhinorrhea have reduced FENO, irrespective of their respiratory history.

AB - In infants, the effect of colds and other respiratory tract infections (RTI) on exhaled nitric oxide (FENO) is not clear In this study, we measured FENO in 24 infants (14 boys) who presented with rhinorrhea, with or without Cough but not wheeze. Twelve of these infants had a history of recurrent wheeze. Levels were compared with a group of 23 healthy infants (13 boys). Further, 8 infants (5 with a history of recurrent wheeze) with rhinorrhea were tested after symptoms had resolved. Infants with rhinorrhea had significantly lower FENO than the healthy infants (11.9vs. 23.8 ppb, respectively, P< 0.0007). Levels increased from 7.5 ppb to 34.1 ppb in the 8 infants tested with and without symptoms (P = 0.0002). Infants with rhinorrhea have reduced FENO, irrespective of their respiratory history.

KW - exhaled nitric oxide

KW - infants

KW - rhinorrhea

KW - SINGLE-BREATH

KW - THERAPY

U2 - 10.1002/ppul.20149

DO - 10.1002/ppul.20149

M3 - Article

SN - 8755-6863

VL - 39

SP - 117

EP - 119

JO - Pediatric Pulmonology

JF - Pediatric Pulmonology

ER -

Exhaled nitric oxide is reduced in infants with rhinorrhoea

Abstract

Keywords

Access to Document

Fingerprint

Cite this