Fast field-cycling magnetic resonance imaging: Imagerie de resonance magnétique en champ cyclé

David J Lurie, Silvio Aime, Simona Baroni, Nuala A Booth, Lionel M Broche, Chang-Hoon Choi, Gareth R Davies, Saadiya Ismail, Dara O Hogain, Kerrin J Pine

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Abstract

Magnetic resonance imaging (MRI) and fast field-cycling (FFC) NMR are both well developed methods. The combination of these techniques, namely fast field-cycling magnetic resonance imaging (FFC-MRI) is much less well-known. Nevertheless, FFC-MRI has a number of significant applications and advantages over conventional techniques,and is being pursued in a number of laboratories. This article reviews the progress in FFC-MRI over the last two decades, particularly in the areas of Earth’s field and prepolarised MRI, as well as free radical imaging using field-cycling Overhauser MRI. Different approaches to magnet design for FFC-MRI are also described. The paper then goes on to discuss recent techniques and applications of FFC-MRI, including protein measurement via quadrupolar cross-relaxation, contrast agent studies, localised relaxometry and FFC-MRI with magnetisation-transfer contrast.
Original languageEnglish
Pages (from-to)136-148
Number of pages13
JournalComptes Rendus. Physique
Volume11
Issue number2
DOIs
Publication statusPublished - Mar 2010

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magnetic resonance
cycles
cross relaxation
free radicals
magnets
proteins
magnetization
nuclear magnetic resonance

Keywords

  • fast-field cycling magnetic resonance imaging
  • FFC-MRI
  • Earth-field MRI
  • pre-polarised MRI
  • free-radical imaging
  • magnetisation-transfer contrast

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Fast field-cycling magnetic resonance imaging : Imagerie de resonance magnétique en champ cyclé . / Lurie, David J; Aime, Silvio; Baroni, Simona; Booth, Nuala A; Broche, Lionel M; Choi, Chang-Hoon; Davies, Gareth R; Ismail, Saadiya; O Hogain, Dara; Pine, Kerrin J.

In: Comptes Rendus. Physique, Vol. 11, No. 2, 03.2010, p. 136-148.

Research output: Contribution to journalArticle

Lurie, David J ; Aime, Silvio ; Baroni, Simona ; Booth, Nuala A ; Broche, Lionel M ; Choi, Chang-Hoon ; Davies, Gareth R ; Ismail, Saadiya ; O Hogain, Dara ; Pine, Kerrin J. / Fast field-cycling magnetic resonance imaging : Imagerie de resonance magnétique en champ cyclé . In: Comptes Rendus. Physique. 2010 ; Vol. 11, No. 2. pp. 136-148.
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