Fish Oil Supplementation Reduces Markers of Oxidative Stress But Not Muscle Soreness After Eccentric Exercise

Patrick Gray, Andrew John Chappell, Alison McEwan Jenkinson, Frank Thies, Stuart Robert Gray (Corresponding Author)

Research output: Contribution to journalArticle

33 Citations (Scopus)
6 Downloads (Pure)

Abstract

Due to the potential anti-inflammatory properties of fish-derived long chain n-3 fatty acids, it has been suggested that athletes should regularly consume fish oils, although evidence in support of this recommendation is not clear. While fish oils can positively modulate immune function, it remains possible that, due to their high number of double bonds, there may be concurrent increases in lipid peroxidation. The current study aims to investigate the effect of fish oil supplementation on exercise-induced markers of oxidative stress and muscle damage. Twenty males underwent a six week double blind randomised placebo-controlled supplementation trial involving two groups (fish oil or placebo). After supplementation, participants undertook 200 repetitions of eccentric knee contractions. Blood samples were taken pre-supplementation, post-supplementation, immediately, 24, 48 and 72h post-exercise and muscle soreness/maximal voluntary contraction (MVC) assessed. There were no differences in creatine kinase, protein carbonyls, endogenous DNA damage, muscle soreness or MVC between groups. Plasma thiobarbituric acid reactive substances (TBARS) were lower (P<0.05) at 48 and 72h post exercise and H2O2 stimulated DNA damage was lower (P<0.05) immediately post-exercise in the fish oil, compared with the control group. The current study demonstrates that fish oil supplementation reduces selected markers of oxidative stress after a single bout of eccentric exercise.

Original languageEnglish
Pages (from-to)206-214
Number of pages9
JournalInternational Journal of Sport Nutrition & Exercise Metabolism
Volume24
Issue number2
Early online date20 Nov 2013
DOIs
Publication statusPublished - Apr 2014

Fingerprint

Fish Oils
Myalgia
fish oils
exercise
Oxidative Stress
oxidative stress
Exercise
muscles
DNA damage
DNA Damage
placebos
Placebos
Thiobarbituric Acid Reactive Substances
athletes
knees
Omega-3 Fatty Acids
long chain fatty acids
creatine kinase
Creatine Kinase
anti-inflammatory activity

Keywords

  • exercise
  • fatty acids
  • free radicals
  • muscle
  • force

Cite this

Fish Oil Supplementation Reduces Markers of Oxidative Stress But Not Muscle Soreness After Eccentric Exercise. / Gray, Patrick; Chappell, Andrew John; Jenkinson, Alison McEwan; Thies, Frank; Gray, Stuart Robert (Corresponding Author).

In: International Journal of Sport Nutrition & Exercise Metabolism, Vol. 24, No. 2, 04.2014, p. 206-214.

Research output: Contribution to journalArticle

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