Fluorinase mediated C--18 F bond formation, an enzymatic tool for PET labelling

Hai Deng; Steven L.  Cobb; Antony D. Gee; Andrew Lockhart; Laurent Martarello; Ryan P. McGlinchey; David O'hagan; Mayca Onega

doi:10.1039/B516861A

Fluorinase mediated C--18 F bond formation, an enzymatic tool for PET labelling

Hai Deng, Steven L. Cobb, Antony D. Gee, Andrew Lockhart, Laurent Martarello (Corresponding Author), Ryan P. McGlinchey, David O'hagan (Corresponding Author), Mayca Onega

Chemistry

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75 Citations (Scopus)

Abstract

The fluorinase enzyme from S. cattleya is applied as a catalyst for the efficient incorporation of [18F]-fluoride into [18F]-5'-fluoro-5'-deoxyadenosine, [18F]-5'-fluoro-5'-deoxyinosine and [18F]-5-fluoro-5-deoxyribose for positron emission tomography (PET) applications.

Original language	English
Pages (from-to)	652-654
Number of pages	3
Journal	Chemical Communications
Issue number	6
DOIs	https://doi.org/10.1039/B516861A
Publication status	Published - 18 Jan 2006

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title = "Fluorinase mediated C--18 F bond formation, an enzymatic tool for PET labelling",

abstract = "The fluorinase enzyme from S. cattleya is applied as a catalyst for the efficient incorporation of [18F]-fluoride into [18F]-5'-fluoro-5'-deoxyadenosine, [18F]-5'-fluoro-5'-deoxyinosine and [18F]-5-fluoro-5-deoxyribose for positron emission tomography (PET) applications.",

author = "Hai Deng and Cobb, {Steven L.} and Gee, {Antony D.} and Andrew Lockhart and Laurent Martarello and McGlinchey, {Ryan P.} and David O'hagan and Mayca Onega",

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doi = "10.1039/B516861A",

language = "English",

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journal = "Chemical Communications",

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T1 - Fluorinase mediated C--18 F bond formation, an enzymatic tool for PET labelling

AU - Deng, Hai

AU - Cobb, Steven L.

AU - Gee, Antony D.

AU - Lockhart, Andrew

AU - Martarello, Laurent

AU - McGlinchey, Ryan P.

AU - O'hagan, David

AU - Onega, Mayca

PY - 2006/1/18

Y1 - 2006/1/18

N2 - The fluorinase enzyme from S. cattleya is applied as a catalyst for the efficient incorporation of [18F]-fluoride into [18F]-5'-fluoro-5'-deoxyadenosine, [18F]-5'-fluoro-5'-deoxyinosine and [18F]-5-fluoro-5-deoxyribose for positron emission tomography (PET) applications.

AB - The fluorinase enzyme from S. cattleya is applied as a catalyst for the efficient incorporation of [18F]-fluoride into [18F]-5'-fluoro-5'-deoxyadenosine, [18F]-5'-fluoro-5'-deoxyinosine and [18F]-5-fluoro-5-deoxyribose for positron emission tomography (PET) applications.

U2 - 10.1039/B516861A

DO - 10.1039/B516861A

M3 - Article

C2 - 16446840

SN - 1359-7345

SP - 652

EP - 654

JO - Chemical Communications

JF - Chemical Communications

IS - 6

ER -

Fluorinase mediated C--18 F bond formation, an enzymatic tool for PET labelling

Abstract

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