Formation of 2,4,5-triaryl-4,5-dihydro-1H-imidazoles, (1), from aryl aldehydes. Crystal structures of cis-(1 : aryl=pyridin-2-yl), {trans-[(1 : aryl=pyridin-2-yl)H](+)[OAc](-)center dot 3H(2)O}, {cis-[1 : aryl=thien-2-yl]center dot 0.5H(2)O} and trans-(1 : aryl=thien-2-yl)

Christiane Fernandes, Adolfo Horn, R. Alan Howie, Jan Schripsema, Janet M. S. Skakle, James L. Wardell

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The preparations of cis-2,4,5-triaryl-4,5-dihydro-1H-imidazoles, (aryl = thien-2-yl or pyridin-2-yl) from aryl aldehydes, ammonium chloride and triethylamine in methanol, and their conversions to the trans-isomers are reported. Crystal structures of cis-(1: aryl=pyridin-2-yl), cis-[1: aryl=thien-2-yl.0.5H(2)O], trans-(1: aryl=thien-2-yl), and trans-{[(1: aryl=pyridin-2-yl)H](+)[OAc](-) center dot 3H(2)O), have been determined and compared with related structures. (c) 2006 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)274-283
Number of pages10
JournalJournal of Molecular Structure
Volume837
Issue number1-3
Early online date14 Dec 2006
DOIs
Publication statusPublished - 30 Jun 2007

Keywords

  • 2,4,5-triaryl-4,5-dihydro-1H-imidazoles
  • crystal structures
  • cis-trans-isomerisation
  • aromatic-aldehydes
  • amarine
  • derivatives
  • database
  • ammonia

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