Harnessing the power of multi-omics data for predicting climate change response

Kara Layton, IR Bradbury

Research output: Contribution to journalArticlepeer-review


Predicting how species will respond to future climate change is of central importance in the midst of the global biodiversity crisis, and recent work has demonstrated the utility of population genomics for improving these predictions.
Here, we suggest a broadening of the approach to include other types of genomic variants that play an important role in adaptation, like structural (e.g. copy number variants) and epigenetic variants (e.g. DNA methylation). These data could provide additional power for forecasting response, especially in weakly structured or panmictic species.
Incorporating structural and epigenetic variation into estimates of climate change vulnerability, or maladaptation, may not only improve prediction power but also provide insight into the molecular mechanisms underpinning species’ response to climate change.
Original languageEnglish
JournalJournal of Animal Ecology
Early online date22 Oct 2021
Publication statusE-pub ahead of print - 22 Oct 2021


  • forecasting
  • genomic offset
  • structural variation
  • epigenetic variation
  • panmixia


Dive into the research topics of 'Harnessing the power of multi-omics data for predicting climate change response'. Together they form a unique fingerprint.

Cite this