Harpulliasides A and B: Two new benzeneacetic acid derivatives from Harpullia pendula

Mohamed Salaheldin A. Abdelkader*, Mostafa Rateb, Gamal A. Mohamed, Marcel Jaspars

*Corresponding author for this work

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Two new benzeneacetic acid derivatives, harpulliaside A (1) and harpulliaside B (2), together with five known flavonoid glycosides; quercetin-3-O-beta-D-glucoside (3), kaempferol-3-O-beta-D-glucoside (4), kaempferol-3-O-beta-D-glucopyranosyl-(1 -> 2)-alpha-L-rhamnopyranoside (5), kaempferol-3-O-beta-D-glucopyranosyl-(1 -> 4)-alpha-L-rhamnopyranoside (6), and kaempferol-3-O-beta-D-apiofuranosyl-(1 -> 2)-beta-D-glucopyranoside (7) were isolated and characterized for the first time from the leaves of Harpullia pendula. The structures of these compounds were established by 1D and 2D NMR experiments and HRESIMS analyses. The new compounds were assessed for their antibacterial effect against different Gram-positive and Gram negative bacterial strains. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)131-135
Number of pages5
JournalPhytochemistry letters
Volume15
Early online date11 Dec 2015
DOIs
Publication statusPublished - Mar 2016

Keywords

  • harpullia pendula
  • sapindaceae
  • benzeneacetic acid derivatives
  • harpulliasides A and B
  • flavonoid glycosides
  • antibacterial
  • sophora-flavescens
  • flavonol glycosides
  • chemical constituents
  • cupanioides
  • saponins
  • NMR

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