Importance of the nature of comparison conditions for testing theory-based interventions: reply

Susan Michie, Andrew Prestwich, Marijn de Bruin

Research output: Contribution to journalArticle

15 Citations (Scopus)


The nature of comparison conditions is a much overlooked feature of designing and interpreting the results of randomized controlled trials, as outlined by Williams (see record 2010-18776-001). We agree that understanding the components and mechanisms of the comparison condition is necessary for making inferences about both intervention effectiveness (whether the intervention worked and which components may have contributed to such an effect) and about theoretical mediators (how it worked). The extent to which one can draw strong inferences regarding the efficacy and mechanisms of an intervention over the comparison is conditional upon a number of key points.
Original languageEnglish
Pages (from-to)468-470
Number of pages3
JournalHealth Psychology
Issue number5
Publication statusPublished - Sep 2010



  • behavior therapy
  • conditioning (psychology)
  • humans
  • psychological theory
  • randomized controlled trials as topic
  • therapies, investigational

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