Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae)

S. D. Sarker, A. Laird, L. Nahar, Y. Kumarasamy, Marcel Jaspars

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Abstract

Preparative RP-HPLC analysis of a methanol extract of the seeds of Centaurea cyanus afforded four indole alkaloids: moschamine, cis-moschamine, centcyamine and cis-centcyamine, the latter two being new natural products. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. General toxicity of the isolates was determined by Brine Shrimp Lethality bioassay. (C) 2001 Elsevier Science Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)1273-1276
Number of pages3
JournalPhytochemistry
Volume57
DOIs
Publication statusPublished - 2001

Keywords

  • Centaurea cyanus
  • Compositae
  • Asteraceae
  • indole
  • moschamine
  • centcyamine
  • toxicity
  • Brine Shrimp Lethality bioassay
  • Artemia saliva
  • NMR

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