Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae)

S. D. Sarker; A. Laird; L. Nahar; Y. Kumarasamy; Marcel Jaspars

doi:10.1016/S0031-9422(01)00084-X

Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae)

S. D. Sarker, A. Laird, L. Nahar, Y. Kumarasamy, Marcel Jaspars

Chemistry

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

Abstract

Preparative RP-HPLC analysis of a methanol extract of the seeds of Centaurea cyanus afforded four indole alkaloids: moschamine, cis-moschamine, centcyamine and cis-centcyamine, the latter two being new natural products. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. General toxicity of the isolates was determined by Brine Shrimp Lethality bioassay. (C) 2001 Elsevier Science Ltd. All rights reserved.

Original language	English
Pages (from-to)	1273-1276
Number of pages	3
Journal	Phytochemistry
Volume	57
DOIs	https://doi.org/10.1016/S0031-9422(01)00084-X
Publication status	Published - 2001

Keywords

Centaurea cyanus
Compositae
Asteraceae
indole
moschamine
centcyamine
toxicity
Brine Shrimp Lethality bioassay
Artemia saliva
NMR

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10.1016/S0031-9422(01)00084-X

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title = "Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae)",

abstract = "Preparative RP-HPLC analysis of a methanol extract of the seeds of Centaurea cyanus afforded four indole alkaloids: moschamine, cis-moschamine, centcyamine and cis-centcyamine, the latter two being new natural products. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. General toxicity of the isolates was determined by Brine Shrimp Lethality bioassay. (C) 2001 Elsevier Science Ltd. All rights reserved.",

keywords = "Centaurea cyanus, Compositae, Asteraceae, indole, moschamine, centcyamine, toxicity, Brine Shrimp Lethality bioassay, Artemia saliva, NMR",

author = "Sarker, {S. D.} and A. Laird and L. Nahar and Y. Kumarasamy and Marcel Jaspars",

year = "2001",

doi = "10.1016/S0031-9422(01)00084-X",

language = "English",

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journal = "Phytochemistry",

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TY - JOUR

T1 - Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae)

AU - Sarker, S. D.

AU - Laird, A.

AU - Nahar, L.

AU - Kumarasamy, Y.

AU - Jaspars, Marcel

PY - 2001

Y1 - 2001

N2 - Preparative RP-HPLC analysis of a methanol extract of the seeds of Centaurea cyanus afforded four indole alkaloids: moschamine, cis-moschamine, centcyamine and cis-centcyamine, the latter two being new natural products. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. General toxicity of the isolates was determined by Brine Shrimp Lethality bioassay. (C) 2001 Elsevier Science Ltd. All rights reserved.

AB - Preparative RP-HPLC analysis of a methanol extract of the seeds of Centaurea cyanus afforded four indole alkaloids: moschamine, cis-moschamine, centcyamine and cis-centcyamine, the latter two being new natural products. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. General toxicity of the isolates was determined by Brine Shrimp Lethality bioassay. (C) 2001 Elsevier Science Ltd. All rights reserved.

KW - Centaurea cyanus

KW - Compositae

KW - Asteraceae

KW - indole

KW - moschamine

KW - centcyamine

KW - toxicity

KW - Brine Shrimp Lethality bioassay

KW - Artemia saliva

KW - NMR

U2 - 10.1016/S0031-9422(01)00084-X

DO - 10.1016/S0031-9422(01)00084-X

M3 - Article

SN - 0031-9422

VL - 57

SP - 1273

EP - 1276

JO - Phytochemistry

JF - Phytochemistry

ER -

Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae)

Abstract

Keywords

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