Issues in pediatric asthma

Peter Joseph Benedict Helms

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Different wheezing syndromes can carry the diagnostic label of "asthma," especially in very young children, and an accurate differential diagnosis is essential for improving outcomes, Because presenting symptoms are similar, making a rapid, accurate differential diagnosis is often daunting. Asthma can, eventually, be distinguished from other wheezing disorders based on differences in symptomatology, pathophysiology, and disease evolution. Once diagnosed, inhaled corticosteroids (ICS) remain the cornerstone of treatment in persistent pediatric asthma. Compelling evidence supports the benefits of these agents in reducing asthma-related morbidity and mortality and in preventing airway remodeling. As a result, ICS use in young children with asthma has grown substantially in recent years. Questions are being raised about the appropriateness of early and long-term use of ICS in young children, and whether ICS are overused in this population. Because of the challenges faced by clinicians in differentiating asthma from the other childhood wheezing disorders often present in young children, it may be best to delay the use of regular ICS therapy until a definitive diagnosis can be established. Alternatives to ICS (such as the leukotriene receptor antagonists) should also be considered to avoid the growth-suppressing potential of steroids in the management of mild asthma. (C) 2001 Wiley-Liss. Inc.

Original languageEnglish
Pages (from-to)49-56
Number of pages7
JournalPediatric Pulmonology - Supplement
Volume21
DOIs
Publication statusPublished - 2001

Keywords

  • asthma
  • wheezing syndromes
  • viral-associated wheeze
  • atopy
  • inhaled corticosteroids
  • asthma guidelines
  • children
  • CHILDHOOD ASTHMA
  • INHALED CORTICOSTEROIDS
  • LUNG-FUNCTION
  • PRESCHOOL-CHILDREN
  • PULMONARY-FUNCTION
  • CHRONIC-BRONCHITIS
  • WHEEZY BRONCHITIS
  • DIAGNOSED ASTHMA
  • NATURAL-HISTORY
  • YOUNG-ADULTS

Cite this

Issues in pediatric asthma. / Helms, Peter Joseph Benedict.

In: Pediatric Pulmonology - Supplement, Vol. 21, 2001, p. 49-56.

Research output: Contribution to journalArticle

Helms, Peter Joseph Benedict. / Issues in pediatric asthma. In: Pediatric Pulmonology - Supplement. 2001 ; Vol. 21. pp. 49-56.
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