Leptin - Signals and secretions from white adipose tissue

P  Trayhurn; J H  Beattie; D V  Rayner

Leptin - Signals and secretions from white adipose tissue

P Trayhurn, J H Beattie, D V Rayner

Research output: Chapter in Book/Report/Conference proceeding › Published conference contribution

Abstract

The classical view of white adipose tissue is of an organ concerned with the storage of lipid, responding passively to changes in energy balance. It is now evident that white fat is an important secretory and endocrine organ which plays a wide role in metabolic and physiological regulation. It secretes, in particular, a critical signal in the control of energy balance, i.e. leptin. This hormone is also, implicated in a range of other processes, from reproduction to immunity and angiogenesis. A wide variety of protein secretions from white fat have now been identified, including angiotensinogen, plasminogen activator inhibitor-1, retinol binding protein adiponectin and interleukin-6, and these are associated with processes as diverse as haemostasis and the control of blued pressure. It is clear that white adipose tissue has come 'in from the cold'.

Original language	English
Title of host publication	LIFE IN THE COLD
Editors	G Heldmaier, M Klingenspor
Place of Publication	BERLIN
Publisher	SPRINGER-VERLAG BERLIN
Pages	459-469
Number of pages	11
ISBN (Print)	3-540-67410-1
Publication status	Published - 2000
Event	11th International Hibernation Symposium on Life in the Cold - JUNGHOLZ Duration: 13 Aug 2000 → 18 Aug 2000

Conference

Conference	11th International Hibernation Symposium on Life in the Cold
City	JUNGHOLZ
Period	13/08/00 → 18/08/00

Keywords

RECEPTOR MESSENGER-RNA
PLASMINOGEN-ACTIVATOR INHIBITOR-1
SYMPATHETIC NERVOUS-SYSTEM
IN-SITU HYBRIDIZATION
OBESE GENE-PRODUCT
INSULIN-RESISTANCE
DIABETES-MELLITUS
RAT ADIPOCYTES
FEMALE MICE
BODY-WEIGHT

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

@inproceedings{71ea6b6aebbf46248a34aafb20f279ab,

title = "Leptin - Signals and secretions from white adipose tissue",

abstract = "The classical view of white adipose tissue is of an organ concerned with the storage of lipid, responding passively to changes in energy balance. It is now evident that white fat is an important secretory and endocrine organ which plays a wide role in metabolic and physiological regulation. It secretes, in particular, a critical signal in the control of energy balance, i.e. leptin. This hormone is also, implicated in a range of other processes, from reproduction to immunity and angiogenesis. A wide variety of protein secretions from white fat have now been identified, including angiotensinogen, plasminogen activator inhibitor-1, retinol binding protein adiponectin and interleukin-6, and these are associated with processes as diverse as haemostasis and the control of blued pressure. It is clear that white adipose tissue has come 'in from the cold'.",

keywords = "RECEPTOR MESSENGER-RNA, PLASMINOGEN-ACTIVATOR INHIBITOR-1, SYMPATHETIC NERVOUS-SYSTEM, IN-SITU HYBRIDIZATION, OBESE GENE-PRODUCT, INSULIN-RESISTANCE, DIABETES-MELLITUS, RAT ADIPOCYTES, FEMALE MICE, BODY-WEIGHT",

author = "P Trayhurn and Beattie, {J H} and Rayner, {D V}",

year = "2000",

language = "English",

isbn = "3-540-67410-1",

pages = "459--469",

editor = "G Heldmaier and M Klingenspor",

booktitle = "LIFE IN THE COLD",

publisher = "SPRINGER-VERLAG BERLIN",

note = "11th International Hibernation Symposium on Life in the Cold ; Conference date: 13-08-2000 Through 18-08-2000",

}

TY - GEN

T1 - Leptin - Signals and secretions from white adipose tissue

AU - Trayhurn, P

AU - Beattie, J H

AU - Rayner, D V

PY - 2000

Y1 - 2000

N2 - The classical view of white adipose tissue is of an organ concerned with the storage of lipid, responding passively to changes in energy balance. It is now evident that white fat is an important secretory and endocrine organ which plays a wide role in metabolic and physiological regulation. It secretes, in particular, a critical signal in the control of energy balance, i.e. leptin. This hormone is also, implicated in a range of other processes, from reproduction to immunity and angiogenesis. A wide variety of protein secretions from white fat have now been identified, including angiotensinogen, plasminogen activator inhibitor-1, retinol binding protein adiponectin and interleukin-6, and these are associated with processes as diverse as haemostasis and the control of blued pressure. It is clear that white adipose tissue has come 'in from the cold'.

AB - The classical view of white adipose tissue is of an organ concerned with the storage of lipid, responding passively to changes in energy balance. It is now evident that white fat is an important secretory and endocrine organ which plays a wide role in metabolic and physiological regulation. It secretes, in particular, a critical signal in the control of energy balance, i.e. leptin. This hormone is also, implicated in a range of other processes, from reproduction to immunity and angiogenesis. A wide variety of protein secretions from white fat have now been identified, including angiotensinogen, plasminogen activator inhibitor-1, retinol binding protein adiponectin and interleukin-6, and these are associated with processes as diverse as haemostasis and the control of blued pressure. It is clear that white adipose tissue has come 'in from the cold'.

KW - RECEPTOR MESSENGER-RNA

KW - PLASMINOGEN-ACTIVATOR INHIBITOR-1

KW - SYMPATHETIC NERVOUS-SYSTEM

KW - IN-SITU HYBRIDIZATION

KW - OBESE GENE-PRODUCT

KW - INSULIN-RESISTANCE

KW - DIABETES-MELLITUS

KW - RAT ADIPOCYTES

KW - FEMALE MICE

KW - BODY-WEIGHT

M3 - Published conference contribution

SN - 3-540-67410-1

SP - 459

EP - 469

BT - LIFE IN THE COLD

A2 - Heldmaier, G

A2 - Klingenspor, M

PB - SPRINGER-VERLAG BERLIN

CY - BERLIN

T2 - 11th International Hibernation Symposium on Life in the Cold

Y2 - 13 August 2000 through 18 August 2000

ER -

Leptin - Signals and secretions from white adipose tissue

Abstract

Conference

Keywords

UN SDGs

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