Making thiosulfate-disubstituted-amino-optionally substituted-phenyl-imino-optionally substituted-cyclohexadienylidene-N,N-disubstituted-ammoniums comprises carrying out nitrosyl reduction, thiosulfonic acid formation and oxidative coupling

Research output: Patent

Abstract

Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (mtc)
WO 2015052496 A1


Methods of synthesizing and purifying certain 3,7-diamino-phenothiazin-5-ium compounds (referred to herein as "diaminophenothiazinium compounds") including Methythioninium Chloride (MTC) (also known as Methylene Blue) are provided.
Original languageEnglish
Patent numberWO2015052496 A1
Priority date7/10/13
Publication statusPublished - 16 Apr 2015

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Thiosulfonic Acids
Thiosulfates
Methylene Blue
Chlorides

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title = "Making thiosulfate-disubstituted-amino-optionally substituted-phenyl-imino-optionally substituted-cyclohexadienylidene-N,N-disubstituted-ammoniums comprises carrying out nitrosyl reduction, thiosulfonic acid formation and oxidative coupling",
abstract = "Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (mtc) WO 2015052496 A1Methods of synthesizing and purifying certain 3,7-diamino-phenothiazin-5-ium compounds (referred to herein as {"}diaminophenothiazinium compounds{"}) including Methythioninium Chloride (MTC) (also known as Methylene Blue) are provided.",
author = "Sinclair, {James Peter} and Nicoll, {Sarah Louise} and Storey, {John M. D.}",
year = "2015",
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day = "16",
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type = "Patent",
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AU - Nicoll, Sarah Louise

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AB - Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (mtc) WO 2015052496 A1Methods of synthesizing and purifying certain 3,7-diamino-phenothiazin-5-ium compounds (referred to herein as "diaminophenothiazinium compounds") including Methythioninium Chloride (MTC) (also known as Methylene Blue) are provided.

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