Malaria parasite growth is stimulated by mosquito probing

Peter Francis Billingsley, L. S. Snook, Valerie Jeanetta Johnston

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The ability of malaria parasites to respond positively to the presence of feeding mosquito vectors would clearly be advantageous to transmission. In this study, Anopheles stephensi mosquitoes probed mice infected with the rodent malaria parasite, Plasmodium chabaudi. Growth of asexual stages was accelerated and gametocytes appeared 1-2 days earlier than in controls. This first study, to our knowledge, of the effects of mosquitoes on 'in-host' growth and development of Plasmodium has profound implications for malaria epidemiology, suggesting that individuals exposed to high mosquito numbers can contribute disproportionately high numbers of parasites to the transmission pool.

Original languageEnglish
Pages (from-to)185-189
Number of pages4
JournalBiology Letters
Volume1
Issue number2
DOIs
Publication statusPublished - 2005

Keywords

  • mosquito
  • probing
  • saliva
  • Plasmodium chabaudi
  • gametocytogenesis
  • ANOPHELES-STEPHENSI
  • SALIVARY-GLANDS
  • PLASMODIUM-CHABAUDI
  • INFECTIVITY
  • MICE
  • CULICIDAE
  • DIPTERA
  • VIRUS
  • TRANSMISSION
  • INJECTION

Cite this

Billingsley, P. F., Snook, L. S., & Johnston, V. J. (2005). Malaria parasite growth is stimulated by mosquito probing. Biology Letters, 1(2), 185-189. https://doi.org/10.1098/rsbl.2004.0260