Marine-derived n-3 fatty acids therapy for stroke

Celia Gabriela Alvarez Campano; Mary J. Macleod; Lorna S. Aucott; Frank Thies

doi:10.1161/STROKEAHA.119.026919

Marine-derived n-3 fatty acids therapy for stroke

Celia Gabriela Alvarez Campano^* (Corresponding Author), Mary J. Macleod, Lorna S. Aucott, Frank Thies

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Downloads (Pure)

Abstract

Background

With stroke burden increasing, there remains a need to identify therapeutic options that ameliorate the acute insult. There is substantial evidence for a neuroprotective effect of marine-derived n-3 polyunsaturated fatty acids (PUFAs), associated with better functional outcomes in experimental stroke models.

Objectives

To assess the effects of administration of marine-derived n-3 PUFAs on functional outcomes and dependence in people with stroke.

Our secondary outcomes were vascular-related death, recurrent events, incidence of other type of stroke, adverse events, quality of life, and mood.

Original language	English
Pages (from-to)	e314-e315
Number of pages	2
Journal	Stroke
Volume	50
Issue number	11
Early online date	26 Sept 2019
DOIs	https://doi.org/10.1161/STROKEAHA.119.026919
Publication status	Published - 1 Nov 2019

Bibliographical note

Funding Sources

CG Alvarez Campano’s PhD studies are funded by the Mexican Council for Science and Technology (CONACYT) and the Institute of Innovation and Technology Transfer (I2T2), grant number 457349.

Acknowledgments

This paper is based on a Cochrane Review published in The Cochrane Library 2019, Issue 6 (see www.thecochranelibrary.com for information). Cochrane Reviews are regularly updated as new evidence emerges and in response to feedback, The Cochrane Library should be consulted for the most recent version of the review.

Keywords

stroke
treatment
functional recovery
marine-derived n-3 PUFAs
death
n-3 fatty acids
quality of life
incidence
neuroprotective effect

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1161/STROKEAHA.119.026919Licence: Unspecified

Accepted Manuscript
This is the author's accepted manuscript of an article published in Stroke. The final published version can be found at: https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.026919
Accepted author manuscript, 160 KBLicence: Unspecified

Cite this

@article{9663957f0b30485f934423d90b1bb2aa,

title = "Marine-derived n-3 fatty acids therapy for stroke",

abstract = "BackgroundWith stroke burden increasing, there remains a need to identify therapeutic options that ameliorate the acute insult. There is substantial evidence for a neuroprotective effect of marine-derived n-3 polyunsaturated fatty acids (PUFAs), associated with better functional outcomes in experimental stroke models.ObjectivesTo assess the effects of administration of marine-derived n-3 PUFAs on functional outcomes and dependence in people with stroke.Our secondary outcomes were vascular-related death, recurrent events, incidence of other type of stroke, adverse events, quality of life, and mood.",

keywords = "stroke, treatment, functional recovery, marine-derived n-3 PUFAs, death, n-3 fatty acids, quality of life, incidence, neuroprotective effect",

author = "{Alvarez Campano}, {Celia Gabriela} and Macleod, {Mary J.} and Aucott, {Lorna S.} and Frank Thies",

note = "Funding Sources CG Alvarez Campano{\textquoteright}s PhD studies are funded by the Mexican Council for Science and Technology (CONACYT) and the Institute of Innovation and Technology Transfer (I2T2), grant number 457349. Acknowledgments This paper is based on a Cochrane Review published in The Cochrane Library 2019, Issue 6 (see www.thecochranelibrary.com for information). Cochrane Reviews are regularly updated as new evidence emerges and in response to feedback, The Cochrane Library should be consulted for the most recent version of the review.",

year = "2019",

month = nov,

day = "1",

doi = "10.1161/STROKEAHA.119.026919",

language = "English",

volume = "50",

pages = "e314--e315",

journal = "Stroke",

issn = "0039-2499",

publisher = "Lippincott Williams and Wilkins",

number = "11",

}

TY - JOUR

T1 - Marine-derived n-3 fatty acids therapy for stroke

AU - Alvarez Campano, Celia Gabriela

AU - Macleod, Mary J.

AU - Aucott, Lorna S.

AU - Thies, Frank

N1 - Funding Sources CG Alvarez Campano’s PhD studies are funded by the Mexican Council for Science and Technology (CONACYT) and the Institute of Innovation and Technology Transfer (I2T2), grant number 457349. Acknowledgments This paper is based on a Cochrane Review published in The Cochrane Library 2019, Issue 6 (see www.thecochranelibrary.com for information). Cochrane Reviews are regularly updated as new evidence emerges and in response to feedback, The Cochrane Library should be consulted for the most recent version of the review.

PY - 2019/11/1

Y1 - 2019/11/1

N2 - BackgroundWith stroke burden increasing, there remains a need to identify therapeutic options that ameliorate the acute insult. There is substantial evidence for a neuroprotective effect of marine-derived n-3 polyunsaturated fatty acids (PUFAs), associated with better functional outcomes in experimental stroke models.ObjectivesTo assess the effects of administration of marine-derived n-3 PUFAs on functional outcomes and dependence in people with stroke.Our secondary outcomes were vascular-related death, recurrent events, incidence of other type of stroke, adverse events, quality of life, and mood.

AB - BackgroundWith stroke burden increasing, there remains a need to identify therapeutic options that ameliorate the acute insult. There is substantial evidence for a neuroprotective effect of marine-derived n-3 polyunsaturated fatty acids (PUFAs), associated with better functional outcomes in experimental stroke models.ObjectivesTo assess the effects of administration of marine-derived n-3 PUFAs on functional outcomes and dependence in people with stroke.Our secondary outcomes were vascular-related death, recurrent events, incidence of other type of stroke, adverse events, quality of life, and mood.

KW - stroke

KW - treatment

KW - functional recovery

KW - marine-derived n-3 PUFAs

KW - death

KW - n-3 fatty acids

KW - quality of life

KW - incidence

KW - neuroprotective effect

UR - http://www.scopus.com/inward/record.url?scp=85074243117&partnerID=8YFLogxK

U2 - 10.1161/STROKEAHA.119.026919

DO - 10.1161/STROKEAHA.119.026919

M3 - Article

SN - 0039-2499

VL - 50

SP - e314-e315

JO - Stroke

JF - Stroke

IS - 11

ER -

Marine-derived n-3 fatty acids therapy for stroke

Abstract

Bibliographical note

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this