Marine metabolites and metal ion chelation: intact recovery and identification of an iron(II) complex in the extract of the ascidian Eudistoma gilboviride

Stephen H. Wright, Andrea Raab, Jioji N. Tabudravu, Joerg Feldmann, Paul F. Long, Christopher N. Battershill, Walter C. Dunlap, Bruce F. Milne, Marcel Jaspars

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Sequestering sea squirts: Liquid chromatography with parallel inductively coupled plasma mass spectrometry/electrospray mass spectrometry was used to discover and identify novel lipophilic metal complexes in the solvent extract of the ascidian Eudistoma gilboviride. Using these tools it is now possible to examine whether such complexes play an integral part in an organism's physiology.
Original languageEnglish
Pages (from-to)8090-8092
Number of pages3
JournalAngewandte Chemie International Edition
Volume47
Issue number42
Early online date15 Sept 2008
DOIs
Publication statusPublished - 28 Sept 2008

Keywords

  • analytical methods
  • bioinorganic chemistry
  • chelates
  • mass spectrometry
  • natural products
  • lissoclinum-patella metabolites
  • part 1
  • binding

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