Materials and methods for medical imaging

Timothy Andrew Davies Smith (Inventor), Laurent Alain Claude Trembleau (Inventor), Abbie McLaughlin (Inventor), Michael Simpson (Inventor)

Research output: Patent

Abstract

The invention provides labelled platform conjugates, comprising (i) a labelling platformn (such as a dendrimer or nanoparticle) and (ii) a target binding moiety, wherein the labelling platform has at least one positron emitter attached thereto. The conjugates can be used to flexibly label antibodies or the like, with the positron emitted being added as a simple final step to a positron emitter attachment site, which is a particular advantage when using short halt-life isotopes such as18F. The invention further provides processes and materials for use in preparing the conjugates, and methods of imaging employing them e.g. in Positron Emission Tomography (PET).
Original languageEnglish
Patent numberGB2467494 (A)
IPCWO2009056837
Publication statusPublished - 2010

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positrons
inventions
marking
emitters
platforms
dendrimers
antibodies
attachment
isotopes
tomography
nanoparticles

Cite this

Smith, T. A. D., Trembleau, L. A. C., McLaughlin, A., & Simpson, M. (2010). IPC No. WO2009056837. Materials and methods for medical imaging. (Patent No. GB2467494 (A)).

Materials and methods for medical imaging. / Smith, Timothy Andrew Davies (Inventor); Trembleau, Laurent Alain Claude (Inventor); McLaughlin, Abbie (Inventor); Simpson, Michael (Inventor).

IPC No.: WO2009056837. Patent No.: GB2467494 (A).

Research output: Patent

Smith, TAD, Trembleau, LAC, McLaughlin, A & Simpson, M 2010, Materials and methods for medical imaging, Patent No. GB2467494 (A), IPC No. WO2009056837.
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