Maternal Smoking during Pregnancy and Changes in Prostaglandin Enzymes in the Human Fetus.

Aikaterini Zafeiri; Panagiotis Filis; Sophie Shaw; John P. Iredale; Madeleine J. Swortwood; Rod T. Mitchell; David C. Hay; Peter J. O'Shaughnessy; Paul A. Fowler

doi:10.1177/1933719119834079

Maternal Smoking during Pregnancy and Changes in Prostaglandin Enzymes in the Human Fetus.

Aikaterini Zafeiri, Panagiotis Filis, Sophie Shaw, John P. Iredale, Madeleine J. Swortwood, Rod T. Mitchell, David C. Hay, Peter J. O'Shaughnessy, Paul A. Fowler

Research output: Contribution to journal › Abstract › peer-review

Abstract

Introduction: Prostaglandins (PGs) are inflammatory modulators with important homeostatic and regenerative roles in the liver and their dysregulation can lead to pathological outcomes. Over 20% of pregnant women smoke and smoke constituents that reach the fetal liver can disrupt PG synthesis, contributing to negative outcomes for the offspring. In this study we examined the effect of maternal smoking on PG synthesis pathway in the human fetal liver.

Original language	English
Article number	F-103
Pages (from-to)	244A-244A
Number of pages	1
Journal	Reproductive Sciences
Volume	26
Issue number	Supplement 1
Early online date	14 Feb 2019
DOIs	https://doi.org/10.1177/1933719119834079
Publication status	Published - 1 Mar 2019
Event	66th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI) - Paris, France Duration: 12 Mar 2019 → 16 Mar 2019

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title = "Maternal Smoking during Pregnancy and Changes in Prostaglandin Enzymes in the Human Fetus.",

abstract = " Introduction: Prostaglandins (PGs) are inflammatory modulators with important homeostatic and regenerative roles in the liver and their dysregulation can lead to pathological outcomes. Over 20% of pregnant women smoke and smoke constituents that reach the fetal liver can disrupt PG synthesis, contributing to negative outcomes for the offspring. In this study we examined the effect of maternal smoking on PG synthesis pathway in the human fetal liver.",

author = "Aikaterini Zafeiri and Panagiotis Filis and Sophie Shaw and Iredale, {John P.} and Swortwood, {Madeleine J.} and Mitchell, {Rod T.} and Hay, {David C.} and O'Shaughnessy, {Peter J.} and Fowler, {Paul A.}",

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language = "English",

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journal = "Reproductive Sciences",

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note = "66th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI) ; Conference date: 12-03-2019 Through 16-03-2019",

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TY - JOUR

T1 - Maternal Smoking during Pregnancy and Changes in Prostaglandin Enzymes in the Human Fetus.

AU - Zafeiri, Aikaterini

AU - Filis, Panagiotis

AU - Shaw, Sophie

AU - Iredale, John P.

AU - Swortwood, Madeleine J.

AU - Mitchell, Rod T.

AU - Hay, David C.

AU - O'Shaughnessy, Peter J.

AU - Fowler, Paul A.

PY - 2019/3/1

Y1 - 2019/3/1

N2 - Introduction: Prostaglandins (PGs) are inflammatory modulators with important homeostatic and regenerative roles in the liver and their dysregulation can lead to pathological outcomes. Over 20% of pregnant women smoke and smoke constituents that reach the fetal liver can disrupt PG synthesis, contributing to negative outcomes for the offspring. In this study we examined the effect of maternal smoking on PG synthesis pathway in the human fetal liver.

AB - Introduction: Prostaglandins (PGs) are inflammatory modulators with important homeostatic and regenerative roles in the liver and their dysregulation can lead to pathological outcomes. Over 20% of pregnant women smoke and smoke constituents that reach the fetal liver can disrupt PG synthesis, contributing to negative outcomes for the offspring. In this study we examined the effect of maternal smoking on PG synthesis pathway in the human fetal liver.

U2 - 10.1177/1933719119834079

DO - 10.1177/1933719119834079

M3 - Abstract

VL - 26

SP - 244A-244A

JO - Reproductive Sciences

JF - Reproductive Sciences

SN - 1933-7191

IS - Supplement 1

M1 - F-103

T2 - 66th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI)

Y2 - 12 March 2019 through 16 March 2019

ER -

Maternal Smoking during Pregnancy and Changes in Prostaglandin Enzymes in the Human Fetus.

Abstract

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