Miosis during L-Dopa Therapy

A. S.D. Spiers; D. B. Calne; P. M. Fayers

doi:10.1136/bmj.2.5710.639

Miosis during L-Dopa Therapy

A. S.D. Spiers, D. B. Calne, P. M. Fayers

Applied Health Sciences

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

The pupillary diameter of 11 patients with Parkinson's disease was significantly decreased four hours after ingestion of L-dopa. It is suggested that this miosis may be caused by diminished noradrenaline output at sympathetic nerve endings, or alternatively by an action on the central nervous system.

Original language	English
Pages (from-to)	639-640
Number of pages	2
Journal	British Medical Journal
Volume	2
Issue number	5710
DOIs	https://doi.org/10.1136/bmj.2.5710.639
Publication status	Published - 13 Jun 1970

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title = "Miosis during L-Dopa Therapy",

abstract = "The pupillary diameter of 11 patients with Parkinson's disease was significantly decreased four hours after ingestion of L-dopa. It is suggested that this miosis may be caused by diminished noradrenaline output at sympathetic nerve endings, or alternatively by an action on the central nervous system.",

author = "Spiers, {A. S.D.} and Calne, {D. B.} and Fayers, {P. M.}",

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T1 - Miosis during L-Dopa Therapy

AU - Spiers, A. S.D.

AU - Calne, D. B.

AU - Fayers, P. M.

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N2 - The pupillary diameter of 11 patients with Parkinson's disease was significantly decreased four hours after ingestion of L-dopa. It is suggested that this miosis may be caused by diminished noradrenaline output at sympathetic nerve endings, or alternatively by an action on the central nervous system.

AB - The pupillary diameter of 11 patients with Parkinson's disease was significantly decreased four hours after ingestion of L-dopa. It is suggested that this miosis may be caused by diminished noradrenaline output at sympathetic nerve endings, or alternatively by an action on the central nervous system.

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JO - British Medical Journal

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Miosis during L-Dopa Therapy

Abstract

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