MRC quality of life studies using a daily diary card-practical lessons learned from cancer trials

P. Fayers*

*Corresponding author for this work

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The UK Medical Research Council (MRC) Daily Diary Card for quality of life (QOL) assessment was first designed over ten years ago, and since then has been in continuous use in cancer clinical trials organized by the MRC Cancer Trials Office. However, clinical trials using this technique have only reached maturity since 1989 and later. Thus it is timely to review the experiences gained by use of this method of assessing QOL. Results from a series of clinical trials confirm that the Daily Diary Card appears to be a valid, reliable and sensitive instrument which is able to detect the transient changes in health and QOL which occur on a day to day basis during therapy for cancer. However, in early studies we also encountered a number of problems which were addressed during later MRC trials; we belleve that many of these are of general importance to any investigation of QOL in patients, many of the issues raised remain controversial, and the practical lessons learned from applying the Diary Card will be of relevance to those planning future studies of QOL assessment.

Original languageEnglish
Pages (from-to)343-352
Number of pages10
JournalQuality of Life Research
Volume4
Issue number4
DOIs
Publication statusPublished - Aug 1995

Keywords

  • Cancer patients
  • Daily Diary Card
  • quality of life assessment
  • questionnaire construction
  • questionnaire validity

ASJC Scopus subject areas

  • Nursing(all)
  • Rehabilitation

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