Multifocal and multicentric breast cancer, is it time to think again?

Y. A. Masannat, A. Agrawal, L. Maraqa, M. Fuller, S. K. Down, Ssk Tang, D. Pang, M. Kontos, L. Romics, S. D. Heys

Research output: Contribution to journalArticle


Multifocal multicentric breast cancer has traditionally been considered a contraindication to breast conserving surgery because of concerns regarding locoregional control and risk of disease recurrence. However, the evidence supporting this practice is limited. Increasingly, many breast surgeons are advocating breast conservation in selected cases. This short narrative review summarises current evidence on the role of surgery in multifocal multicentric breast cancer and shows that when technically feasible the option of breast conservation is oncologically safe.

Original languageEnglish
Pages (from-to)62-66
Number of pages5
JournalAnnals of the Royal College of Surgeons of England
Issue number1
Early online date6 Sep 2019
Publication statusPublished - 1 Jan 2020



  • breast cancer
  • Breast conserving surgery
  • Mastectomy
  • Multicentric
  • Multifocal
  • Oncoplastic surgery
  • Humans
  • Treatment Outcome
  • Mastectomy, Segmental/methods
  • Feasibility Studies
  • Practice Patterns, Physicians'
  • Breast Neoplasms/mortality
  • Mastectomy/methods
  • Epidemiologic Methods
  • Clinical Decision-Making
  • Female

ASJC Scopus subject areas

  • Surgery

Cite this

Masannat, Y. A., Agrawal, A., Maraqa, L., Fuller, M., Down, S. K., Tang, S., Pang, D., Kontos, M., Romics, L., & Heys, S. D. (2020). Multifocal and multicentric breast cancer, is it time to think again? Annals of the Royal College of Surgeons of England, 102(1), 62-66.