@article{18506d56381f4dceaf2be136bfe9a861,
title = "Nitrosative and oxidative stress responses in fungal pathogenicity",
abstract = "Fungal pathogenicity has arisen in polyphyletic manner during evolution, yielding fungal pathogens with diverse infection strategies and with differing degrees of evolutionary adaptation to their human host. Not surprisingly, these fungal pathogens display differing degrees of resistance to the reactive oxygen and nitrogen species used by human cells to counteract infection. Furthermore, whilst evolutionarily conserved regulators, such as Hog1, are central to such stress responses in many fungal pathogens, species-specific differences in their roles and regulation abound. In contrast, there is a high degree of commonality in the cellular responses to reactive oxygen and nitrogen species evoked in evolutionarily divergent fungal pathogens.",
keywords = "antifungal agents, fungi, host-pathogen interactions, humans, models, biological, nitroso compounds, oxidants, oxidative stress, stress, physiological",
author = "Brown, {Alistair J P} and Ken Haynes and Janet Quinn",
note = "A paid open access option is available for this journal. Voluntary deposit by author of pre-print allowed on Institutions open scholarly website and pre-print servers Voluntary deposit by author of authors post-print allowed on institutions open scholarly website including Institutional Repository Deposit due to Funding Body, Institutional and Governmental mandate only allowed where separate agreement between repository and publisher exists Set statement to accompany deposit Published source must be acknowledged Must link to journal home page or articles' DOI Publisher's version/PDF cannot be used Articles in some journals can be made Open Access on payment of additional charge NIH Authors articles will be submitted to PubMed Central after <num>12</num> <period units={"}month{"}>months</period> Authors who are required to deposit in subject-based repositories may also use Sponsorship Option",
year = "2009",
month = aug,
doi = "10.1016/j.mib.2009.06.007",
language = "English",
volume = "12",
pages = "384--391",
journal = "Current Opinion in Microbiology",
issn = "1369-5274",
publisher = "Elsevier Limited",
number = "4",
}