Non-specific immune responses in families of Atlantic salmon, Salmo salar, exhibiting differential resistance to furunculosis

M. J. Marsden, L. C. Freeman, D. Cox, C. J. Secombes*

*Corresponding author for this work

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

A variety of non-specific humoral and cellular immune-parameters were investigated in five families of farmed Atlantic salmon, Salmo salar, known to exhibit differential susceptibilities to furunculosis in the field (fishfarm) situation. Non-specific phagocyte functions, such as respiratory burst activity and migration, were not found to be significantly different between resistant and susceptible families. Both complement and non-α 2 macroglobulin (α 2 m)-antiprotease activity were found to be higher in families of salmon resistant to Aeromonas salmonicida, however, these differences were not significant. Nevertheless, significant (P < 0.05) inverse correlations between both non-specific humoral factors and furunculosis mortalities in two independent data sets were observed. Based on the above observations, both complement and non-α 2 m-antiprotease activities appear to play a role in resistance against A. salmonicida.

Original languageEnglish
Pages (from-to)1-16
Number of pages16
JournalAquaculture
Volume146
Issue number1-2
DOIs
Publication statusPublished - 30 Oct 1996

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furunculosis
Aeromonas salmonicida
immune response
Salmo salar
complement
macroglobulins
phagocytes
salmon
mortality
family

Keywords

  • Aeromonas salmonicida
  • Antiprotease
  • Atlantic salmon
  • Complement
  • Differential resistance
  • Immune responses

ASJC Scopus subject areas

  • Aquatic Science

Cite this

Non-specific immune responses in families of Atlantic salmon, Salmo salar, exhibiting differential resistance to furunculosis. / Marsden, M. J.; Freeman, L. C.; Cox, D.; Secombes, C. J.

In: Aquaculture, Vol. 146, No. 1-2, 30.10.1996, p. 1-16.

Research output: Contribution to journalArticle

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