Phenomenological modeling of DNA overstretching

Ray W. Ogden, Giuseppe Saccomandi, Ivonne Sgura

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A phenomenological model based on the three-dimensional theory of nonlinear elasticity is developed to describe the phenomenon of overstretching in the force-extension curve for double-stranded DNA (dsDNA). By using the concept of a material with multiple reference configurations a single formula is obtained to fit the force-extension curve.
Original languageEnglish
Pages (from-to)411-427
Number of pages17
JournalJournal of Nonlinear Mathematical Physics
Volume18
Issue numberSupplement 2
DOIs
Publication statusPublished - 2011

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Keywords

  • force-extension curve
  • DNA overstretching
  • nonlinear elasticity
  • limiting chain extensibility
  • worm-like-chain formula
  • nonlinear least squares

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