Abstract
Oil-based mud, a complex mixture containing amines in emulsifiers, is used in offshore drilling operations. It is a skin irritant that occasionally gives rise to allergic contact sensitivity. In patch testing patients with allergy to drilling mud, we have identified polyamine (diethylenetriamine and triethylenetetramine) sensitivity in 5 patients. All 5 patients were also allergic to emulsifiers. These emulsifiers are cross-linked fatty acid amido-amines, in which unreacted amine groups are thought to cross-sensitize with these constituent polyamines. Cross-reactivity between ethylenediamine, diethylenetetramine and triethylenetetramine was found in 9 subjects.
| Original language | English |
|---|---|
| Pages (from-to) | 326-329 |
| Number of pages | 4 |
| Journal | Contact Dermatitis |
| Volume | 21 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1 Nov 1989 |
Keywords
- Adult
- Chemical Industry
- Dermatitis, Contact
- Dermatitis, Occupational
- Emulsions
- Ethylenediamines
- Humans
- Lubrication
- Male
- Middle Aged
- Mineral Oil
- Petroleum
- Polyamines
- Triethylenetetramine
- drilling fluid
- diethylenetriamine
- triethylnetetramine
- ethylenediamine
- oil based mud
- irritant contact dermatitis
- allergic contact dermatitis
- occupational
- North Sea
- oil and gas industry
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Cite this
Ormerod, A., Wakeel, R. A., Mann, T. A., Main, A., & Aldridge, R. D. (1989). Polyamine sensitization in offshore workers handling drilling muds. Contact Dermatitis, 21(5), 326-329. https://doi.org/10.1111/j.1600-0536.1989.tb04752.x