Polyamine sensitization in offshore workers handling drilling muds

Anthony Ormerod; R A Wakeel; T A Mann; Alan Main; R D Aldridge

doi:10.1111/j.1600-0536.1989.tb04752.x

Polyamine sensitization in offshore workers handling drilling muds

Anthony Ormerod, R A Wakeel, T A Mann, Alan Main, R D Aldridge

Applied Medicine

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Oil-based mud, a complex mixture containing amines in emulsifiers, is used in offshore drilling operations. It is a skin irritant that occasionally gives rise to allergic contact sensitivity. In patch testing patients with allergy to drilling mud, we have identified polyamine (diethylenetriamine and triethylenetetramine) sensitivity in 5 patients. All 5 patients were also allergic to emulsifiers. These emulsifiers are cross-linked fatty acid amido-amines, in which unreacted amine groups are thought to cross-sensitize with these constituent polyamines. Cross-reactivity between ethylenediamine, diethylenetetramine and triethylenetetramine was found in 9 subjects.

Original language	English
Pages (from-to)	326-329
Number of pages	4
Journal	Contact Dermatitis
Volume	21
Issue number	5
DOIs	https://doi.org/10.1111/j.1600-0536.1989.tb04752.x
Publication status	Published - 1 Nov 1989

Keywords

Adult
Chemical Industry
Dermatitis, Contact
Dermatitis, Occupational
Emulsions
Ethylenediamines
Humans
Lubrication
Male
Middle Aged
Mineral Oil
Petroleum
Polyamines
Triethylenetetramine
drilling fluid
diethylenetriamine
triethylnetetramine
ethylenediamine
oil based mud
irritant contact dermatitis
allergic contact dermatitis
occupational
North Sea
oil and gas industry

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10.1111/j.1600-0536.1989.tb04752.x

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title = "Polyamine sensitization in offshore workers handling drilling muds",

abstract = "Oil-based mud, a complex mixture containing amines in emulsifiers, is used in offshore drilling operations. It is a skin irritant that occasionally gives rise to allergic contact sensitivity. In patch testing patients with allergy to drilling mud, we have identified polyamine (diethylenetriamine and triethylenetetramine) sensitivity in 5 patients. All 5 patients were also allergic to emulsifiers. These emulsifiers are cross-linked fatty acid amido-amines, in which unreacted amine groups are thought to cross-sensitize with these constituent polyamines. Cross-reactivity between ethylenediamine, diethylenetetramine and triethylenetetramine was found in 9 subjects.",

keywords = "Adult, Chemical Industry, Dermatitis, Contact, Dermatitis, Occupational, Emulsions, Ethylenediamines, Humans, Lubrication, Male, Middle Aged, Mineral Oil, Petroleum, Polyamines, Triethylenetetramine, drilling fluid, diethylenetriamine, triethylnetetramine, ethylenediamine, oil based mud, irritant contact dermatitis, allergic contact dermatitis, occupational , North Sea , oil and gas industry",

author = "Anthony Ormerod and Wakeel, {R A} and Mann, {T A} and Alan Main and Aldridge, {R D}",

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doi = "10.1111/j.1600-0536.1989.tb04752.x",

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T1 - Polyamine sensitization in offshore workers handling drilling muds

AU - Ormerod, Anthony

AU - Wakeel, R A

AU - Mann, T A

AU - Main, Alan

AU - Aldridge, R D

PY - 1989/11/1

Y1 - 1989/11/1

N2 - Oil-based mud, a complex mixture containing amines in emulsifiers, is used in offshore drilling operations. It is a skin irritant that occasionally gives rise to allergic contact sensitivity. In patch testing patients with allergy to drilling mud, we have identified polyamine (diethylenetriamine and triethylenetetramine) sensitivity in 5 patients. All 5 patients were also allergic to emulsifiers. These emulsifiers are cross-linked fatty acid amido-amines, in which unreacted amine groups are thought to cross-sensitize with these constituent polyamines. Cross-reactivity between ethylenediamine, diethylenetetramine and triethylenetetramine was found in 9 subjects.

AB - Oil-based mud, a complex mixture containing amines in emulsifiers, is used in offshore drilling operations. It is a skin irritant that occasionally gives rise to allergic contact sensitivity. In patch testing patients with allergy to drilling mud, we have identified polyamine (diethylenetriamine and triethylenetetramine) sensitivity in 5 patients. All 5 patients were also allergic to emulsifiers. These emulsifiers are cross-linked fatty acid amido-amines, in which unreacted amine groups are thought to cross-sensitize with these constituent polyamines. Cross-reactivity between ethylenediamine, diethylenetetramine and triethylenetetramine was found in 9 subjects.

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KW - triethylnetetramine

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KW - allergic contact dermatitis

KW - occupational

KW - North Sea

KW - oil and gas industry

U2 - 10.1111/j.1600-0536.1989.tb04752.x

DO - 10.1111/j.1600-0536.1989.tb04752.x

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VL - 21

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JO - Contact Dermatitis

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SN - 0105-1873

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