Polyamine sensitization in offshore workers handling drilling muds

Anthony Ormerod, R A Wakeel, T A Mann, Alan Main, R D Aldridge

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Oil-based mud, a complex mixture containing amines in emulsifiers, is used in offshore drilling operations. It is a skin irritant that occasionally gives rise to allergic contact sensitivity. In patch testing patients with allergy to drilling mud, we have identified polyamine (diethylenetriamine and triethylenetetramine) sensitivity in 5 patients. All 5 patients were also allergic to emulsifiers. These emulsifiers are cross-linked fatty acid amido-amines, in which unreacted amine groups are thought to cross-sensitize with these constituent polyamines. Cross-reactivity between ethylenediamine, diethylenetetramine and triethylenetetramine was found in 9 subjects.
Original languageEnglish
Pages (from-to)326-329
Number of pages4
JournalContact Dermatitis
Volume21
Issue number5
DOIs
Publication statusPublished - 1 Nov 1989

Fingerprint

Polyamines
Trientine
Amines
ethylenediamine
Irritants
Contact Dermatitis
Complex Mixtures
Hypersensitivity
Oils
Fatty Acids
Skin

Keywords

  • Adult
  • Chemical Industry
  • Dermatitis, Contact
  • Dermatitis, Occupational
  • Emulsions
  • Ethylenediamines
  • Humans
  • Lubrication
  • Male
  • Middle Aged
  • Mineral Oil
  • Petroleum
  • Polyamines
  • Triethylenetetramine
  • drilling fluid
  • diethylenetriamine
  • triethylnetetramine
  • ethylenediamine
  • oil based mud
  • irritant contact dermatitis
  • allergic contact dermatitis
  • occupational
  • North Sea
  • oil and gas industry

Cite this

Ormerod, A., Wakeel, R. A., Mann, T. A., Main, A., & Aldridge, R. D. (1989). Polyamine sensitization in offshore workers handling drilling muds. Contact Dermatitis, 21(5), 326-329. https://doi.org/10.1111/j.1600-0536.1989.tb04752.x

Polyamine sensitization in offshore workers handling drilling muds. / Ormerod, Anthony; Wakeel, R A; Mann, T A; Main, Alan; Aldridge, R D.

In: Contact Dermatitis, Vol. 21, No. 5, 01.11.1989, p. 326-329.

Research output: Contribution to journalArticle

Ormerod, A, Wakeel, RA, Mann, TA, Main, A & Aldridge, RD 1989, 'Polyamine sensitization in offshore workers handling drilling muds', Contact Dermatitis, vol. 21, no. 5, pp. 326-329. https://doi.org/10.1111/j.1600-0536.1989.tb04752.x
Ormerod, Anthony ; Wakeel, R A ; Mann, T A ; Main, Alan ; Aldridge, R D. / Polyamine sensitization in offshore workers handling drilling muds. In: Contact Dermatitis. 1989 ; Vol. 21, No. 5. pp. 326-329.
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