Pragmatic multi-centre randomised trial of (1) routine postoperative ICU care and/or (2) pre-operative fluid loading in high-risk surgical patients undergoing major elective and urgent surgery

B Cuthbertson, Marion Kay Campbell, S Stott, Luke David Vale, John David Taylor Norrie, J Kinsella, Jonathan Alistair Cook, Julie Brittenden, Adrian Maxwell Grant, D Alcorn, M Serpell, S McColl, D Rae, K Shepherd, J Addison, Gladys Campbell McPherson, Alison Mary McDonald, Seonaidh Claire Cotton, Andrew Steven Elders, Graeme Stewart MacLennanDwayne Boyers, Rodolfo Andrés Hernández

Research output: Book/ReportCommissioned Report


Patients undergoing major elective or urgent surgery are at high risk of death or significant morbidity. Measures to reduce this morbidity and mortality include pre-operative optimisation and use of higher levels of dependency care after surgery. We propose a pragmatic multi-centre randomised controlled trial of level of
dependency and pre-operative fluid therapy in high-risk surgical patients undergoing major elective surgery.
Original languageEnglish
Place of PublicationEdinburgh, United Kingdom
PublisherChief Scientist Office
Number of pages7
Publication statusPublished - 2010


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