Pregnancy outcome after treatment for cervical intraepithelial neoplasia

Smruta Shanbhag; Heather Clark; Vkc Timmaraju; Siladitya Bhattacharya; Margaret Cruickshank

doi:10.1097/AOG.0b013e3181b5cba3

Pregnancy outcome after treatment for cervical intraepithelial neoplasia

Smruta Shanbhag, Heather Clark, Vkc Timmaraju, Siladitya Bhattacharya, Margaret Cruickshank

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Abstract

OBJECTIVE: To estimate the rate of spontaneous preterm delivery and preterm premature rupture of membranes (PROM) in women with cervical intraepithelial neoplasia (CIN) 3. METHODS: This retrospective cohort analysis was performed on routinely collected Scottish national data. The exposed cohort comprised all women with CIN3; the unexposed cohort were women with no record of CIN. Further comparisons were made within the exposed cohort based on the type of treatment they had for CIN3. The primary outcomes were spontaneous preterm delivery and preterm PROM in their first pregnancies. RESULTS: Women with CIN3 were significantly more likely to have spontaneous preterm deliveries (11% compared with 6%, odds ratio [OR] 1.52, 95% confidence interval [CI] 1.29-1.80, P

Original language	English
Pages (from-to)	727-735
Number of pages	9
Journal	Obstetrics & Gynecology
Volume	114
Issue number	4
DOIs	https://doi.org/10.1097/AOG.0b013e3181b5cba3
Publication status	Published - Oct 2009

Keywords

ablation techniques
adult
case-control studies
cervical intraepithelial neoplasia
cohort studies
conization
electrosurgery
female
fetal membranes, premature rupture
humans
middle aged
odds ratio
pregnancy
premature birth
registries
retrospective studies
uterine cervical neoplasms
young adult

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10.1097/AOG.0b013e3181b5cba3

Cite this

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title = "Pregnancy outcome after treatment for cervical intraepithelial neoplasia",

abstract = "OBJECTIVE: To estimate the rate of spontaneous preterm delivery and preterm premature rupture of membranes (PROM) in women with cervical intraepithelial neoplasia (CIN) 3. METHODS: This retrospective cohort analysis was performed on routinely collected Scottish national data. The exposed cohort comprised all women with CIN3; the unexposed cohort were women with no record of CIN. Further comparisons were made within the exposed cohort based on the type of treatment they had for CIN3. The primary outcomes were spontaneous preterm delivery and preterm PROM in their first pregnancies. RESULTS: Women with CIN3 were significantly more likely to have spontaneous preterm deliveries (11% compared with 6%, odds ratio [OR] 1.52, 95% confidence interval [CI] 1.29-1.80, P",

keywords = "ablation techniques, adult, case-control studies, cervical intraepithelial neoplasia, cohort studies, conization, electrosurgery, female, fetal membranes, premature rupture, humans, middle aged, odds ratio, pregnancy, premature birth, registries, retrospective studies, uterine cervical neoplasms, young adult",

author = "Smruta Shanbhag and Heather Clark and Vkc Timmaraju and Siladitya Bhattacharya and Margaret Cruickshank",

year = "2009",

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T1 - Pregnancy outcome after treatment for cervical intraepithelial neoplasia

AU - Shanbhag, Smruta

AU - Clark, Heather

AU - Timmaraju, Vkc

AU - Bhattacharya, Siladitya

AU - Cruickshank, Margaret

PY - 2009/10

Y1 - 2009/10

N2 - OBJECTIVE: To estimate the rate of spontaneous preterm delivery and preterm premature rupture of membranes (PROM) in women with cervical intraepithelial neoplasia (CIN) 3. METHODS: This retrospective cohort analysis was performed on routinely collected Scottish national data. The exposed cohort comprised all women with CIN3; the unexposed cohort were women with no record of CIN. Further comparisons were made within the exposed cohort based on the type of treatment they had for CIN3. The primary outcomes were spontaneous preterm delivery and preterm PROM in their first pregnancies. RESULTS: Women with CIN3 were significantly more likely to have spontaneous preterm deliveries (11% compared with 6%, odds ratio [OR] 1.52, 95% confidence interval [CI] 1.29-1.80, P

AB - OBJECTIVE: To estimate the rate of spontaneous preterm delivery and preterm premature rupture of membranes (PROM) in women with cervical intraepithelial neoplasia (CIN) 3. METHODS: This retrospective cohort analysis was performed on routinely collected Scottish national data. The exposed cohort comprised all women with CIN3; the unexposed cohort were women with no record of CIN. Further comparisons were made within the exposed cohort based on the type of treatment they had for CIN3. The primary outcomes were spontaneous preterm delivery and preterm PROM in their first pregnancies. RESULTS: Women with CIN3 were significantly more likely to have spontaneous preterm deliveries (11% compared with 6%, odds ratio [OR] 1.52, 95% confidence interval [CI] 1.29-1.80, P

KW - ablation techniques

KW - adult

KW - case-control studies

KW - cervical intraepithelial neoplasia

KW - cohort studies

KW - conization

KW - electrosurgery

KW - female

KW - fetal membranes, premature rupture

KW - humans

KW - middle aged

KW - odds ratio

KW - pregnancy

KW - premature birth

KW - registries

KW - retrospective studies

KW - uterine cervical neoplasms

KW - young adult

U2 - 10.1097/AOG.0b013e3181b5cba3

DO - 10.1097/AOG.0b013e3181b5cba3

M3 - Article

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SN - 0029-7844

VL - 114

SP - 727

EP - 735

JO - Obstetrics & Gynecology

JF - Obstetrics & Gynecology

IS - 4

ER -

Pregnancy outcome after treatment for cervical intraepithelial neoplasia

Abstract

Keywords

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