Prevalence of progressive supranuclear palsy and corticobasal syndrome in Scotland

Diane Swallow* (Corresponding Author), Carl Counsell

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Introduction We estimated the point prevalence of progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) at regional and national levels in Scotland, UK as there are few high-quality prevalence studies of these conditions. Methods Nationally, multiple methods of case ascertainment were used including clinician and nurse specialist referral, searches of ICD-10 diagnostic coding in routinely collected electronic health data (Scottish Morbidity Record), and patient self-referral. In one region we also searched GP databases and unselected hospital correspondence. Cases were verified by clinical examination or medical record review. National and regional total and age-sex stratified crude prevalence rates on 31st December 2018 were calculated. Results The regional crude point prevalence was 4.28 per 100,000 (95% CI 2.90, 6.31) for PSP, and 2.05 per 100,000 (95% CI 1.17, 3.59) for CBS. The national crude prevalence rates were lower due to the greater reliance on passive case ascertainment. There were no clear sex differences. At a national level, the peak crude prevalence rate for both PSP and CBS was in the 70-79 age-group. Discussion The prevalence rates of PSP and CBS were similar to previous estimates with little change over the past 20 years.

Original languageEnglish
Pages (from-to)291–297
Number of pages7
Issue number4
Early online date2 Jun 2022
Publication statusPublished - 2 Jun 2022


  • progressive supranuclear palsy
  • corticobasal degeneration
  • corticobasal syndrome
  • prevalence
  • epidemiology


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