@article{8db4c73bc6a64a9492d2a5ba817d4b13,
title = "Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040",
abstract = "A new siderophore containing a 4,5-dihydroimidazole moiety was isolated from Pseudoalteromonas piscicida S2040 together with myxochelins A and B, alteramide A and its cycloaddition product, and bromo- and dibromoalterochromides. The structure of pseudochelin A was established by spectroscopic techniques including 2D NMR and MS/MS fragmentation data. In bioassays selected fractions of the crude extract of S2040 inhibited the opportunistic pathogen Pseudomonas aeruginosa. Pseudochelin A displayed siderophore activity in the chrome azurol S assay at concentrations higher than 50 μM, and showed weak activity against the fungus Aspergillus fumigatus, but did not display antibacterial, anti-inflammatory or anticonvulsant activity.",
keywords = "LCMS, NMR, Pseudoalteromonas, Pseudochelin A, Siderophore",
author = "Sonnenschein, {Eva C.} and Marc Stierhof and Stephan Goralczyk and Vabre, {Floriane M.} and Leonie Pellissier and Hanssen, {Kine {\O}stnes} and {de la Cruz}, Mercedes and Caridad D{\'i}az and {de Witte}, Peter and Dani{\"e}lle Copmans and Andersen, {Jeanette Hammer} and Espen Hansen and Venke Kristoffersen and Tormo, {Jos{\'e} R.} and Rainer Ebel and Milne, {Bruce F.} and Hai Deng and Lone Gram and Marcel Jaspars and Tabudravu, {Jioji N.}",
note = "Acknowledgements This work was supported by the EU seventh Framework Programme Project {\textquoteleft}PharmaSea{\textquoteright} (Grant agreement no. 312184). BFM acknowledges funding from the Portuguese Foundation for Science and Technology (CONT_DOUT/11/UC/405/10150/18/2008), and thanks DIPC and CFM (UPV/EHU) and the Laboratory for Advanced Computation (University of Coimbra) for support.",
year = "2017",
month = may,
day = "4",
doi = "10.1016/j.tet.2017.03.051",
language = "English",
volume = "73",
pages = "2633--2637",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "PERGAMON-ELSEVIER SCIENCE LTD",
number = "18",
}