QUANTITATIVE AND NON-INVASIVE DETECTION OF PROTEOGLYCAN BY FAST FIELD-CYCLING NUCLEAR MAGNETIC RESONANCE

L. M. Broche, G. P. Ashcroft, D. J. Lurie

Research output: Contribution to journalAbstractpeer-review

Abstract

Purpose: Fast-field cycling MRI (FFC MRI) is a new technique of magnetic resonance imaging that allows non-invasive, contrast agent-free and quantitative detection of certain immobile proteins. This study shows that proteoglycans can be detected by field-cycled NMR (FFC NMR) techniques and that the results correlate with the state of the sample (healthy or diseased). Since protein loss occurs at early stages of osteoarthritis, it is expected that this technique may provide early information on the disease.
Original languageEnglish
Pages (from-to)S92-S93
Number of pages2
JournalOsteoarthritis and Cartilage
Volume20
DOIs
Publication statusPublished - Apr 2012
EventWorld Congress on Osteoarthritis - Barcelona, Spain
Duration: 26 Apr 201229 Apr 2012

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