Recommendations from Cochrane reviews for improving future trials on anesthesia and pain: a meta-research study

Renata Runjic, Mia Plenkovic, Stefania Pirosca, M. Clarke, Shaun Treweek, Livia Puljak* (Corresponding Author)

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Background: Cochrane systematic reviews (CSRs) have a section ‘Implications for research’where the authors make suggestions for improving future research. We assessed the prevalence and time dynamics of different recommendations in the CSRs about anaesthesia and pain.
Methods: We included all CSRs published by the Cochrane Anaesthesia Group (CA Group) and Cochrane Pain and Palliative Care Group (PaPaS Group) before July 17, 2020. We analysed recommendations for improving future research listed in the ‘Implications for research’ section of these CSRs and categorized recommendations for improvements.
Results: We analyzed 370 reviews. Four categories of recommendations were present in more than 40% of reviews. Most reviews recommended a larger sample size and better outcome choice, study design and choice of future intervention. These recommendations gradually increased in frequency in PaPaS Group and mainly decreased in CA Group.
Conclusions: Recommendations from CSRs offer useful advice for trialists designing new trials.
Original languageEnglish
JournalJournal of Comparative Effectiveness Research
Early online date13 May 2022
DOIs
Publication statusE-pub ahead of print - 13 May 2022

Keywords

  • Anaesthesia
  • Pain
  • Cochrane Systematic Review
  • Implications for Research

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