Role of the placenta in regulation of fetal iron status

Harry J McArdle, Christine Lang, Helen Hayes, Lorraine Gambling

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

During pregnancy, the developing fetus is entirely dependent on its mother for nutrition and waste disposal, which take place almost exclusively across the placenta. The placenta is, however, not just a passive mediator; it can also regulate the rates and amounts of nutrient transported. This is particularly true for iron transport. This review examines how the fetus, and not the mother, regulates iron uptake and transfer across the placenta, how these processes interact, and how the fetus can modulate iron metabolism in the mother.
Original languageEnglish
Pages (from-to)S17-22
Number of pages6
JournalNutrition Research Reviews
Volume69
Issue numberSuppl 1
DOIs
Publication statusPublished - Nov 2011

Fingerprint

Placenta
Fetus
Iron
Food
Pregnancy

Keywords

  • Biological Transport
  • Female
  • Fetal Development
  • Fetus
  • Humans
  • Iron, Dietary
  • Maternal-Fetal Exchange
  • Placenta
  • Placental Circulation
  • Pregnancy

Cite this

Role of the placenta in regulation of fetal iron status. / McArdle, Harry J; Lang, Christine; Hayes, Helen; Gambling, Lorraine.

In: Nutrition Research Reviews, Vol. 69, No. Suppl 1, 11.2011, p. S17-22.

Research output: Contribution to journalArticle

McArdle, Harry J ; Lang, Christine ; Hayes, Helen ; Gambling, Lorraine. / Role of the placenta in regulation of fetal iron status. In: Nutrition Research Reviews. 2011 ; Vol. 69, No. Suppl 1. pp. S17-22.
@article{0fa35982683140018d9145ace197ed6f,
title = "Role of the placenta in regulation of fetal iron status",
abstract = "During pregnancy, the developing fetus is entirely dependent on its mother for nutrition and waste disposal, which take place almost exclusively across the placenta. The placenta is, however, not just a passive mediator; it can also regulate the rates and amounts of nutrient transported. This is particularly true for iron transport. This review examines how the fetus, and not the mother, regulates iron uptake and transfer across the placenta, how these processes interact, and how the fetus can modulate iron metabolism in the mother.",
keywords = "Biological Transport, Female, Fetal Development, Fetus, Humans, Iron, Dietary, Maternal-Fetal Exchange, Placenta, Placental Circulation, Pregnancy",
author = "McArdle, {Harry J} and Christine Lang and Helen Hayes and Lorraine Gambling",
note = "{\circledC} 2011 International Life Sciences Institute.",
year = "2011",
month = "11",
doi = "10.1111/j.1753-4887.2011.00428.x",
language = "English",
volume = "69",
pages = "S17--22",
journal = "Nutrition Research Reviews",
issn = "0954-4224",
publisher = "Wiley-Blackwell",
number = "Suppl 1",

}

TY - JOUR

T1 - Role of the placenta in regulation of fetal iron status

AU - McArdle, Harry J

AU - Lang, Christine

AU - Hayes, Helen

AU - Gambling, Lorraine

N1 - © 2011 International Life Sciences Institute.

PY - 2011/11

Y1 - 2011/11

N2 - During pregnancy, the developing fetus is entirely dependent on its mother for nutrition and waste disposal, which take place almost exclusively across the placenta. The placenta is, however, not just a passive mediator; it can also regulate the rates and amounts of nutrient transported. This is particularly true for iron transport. This review examines how the fetus, and not the mother, regulates iron uptake and transfer across the placenta, how these processes interact, and how the fetus can modulate iron metabolism in the mother.

AB - During pregnancy, the developing fetus is entirely dependent on its mother for nutrition and waste disposal, which take place almost exclusively across the placenta. The placenta is, however, not just a passive mediator; it can also regulate the rates and amounts of nutrient transported. This is particularly true for iron transport. This review examines how the fetus, and not the mother, regulates iron uptake and transfer across the placenta, how these processes interact, and how the fetus can modulate iron metabolism in the mother.

KW - Biological Transport

KW - Female

KW - Fetal Development

KW - Fetus

KW - Humans

KW - Iron, Dietary

KW - Maternal-Fetal Exchange

KW - Placenta

KW - Placental Circulation

KW - Pregnancy

U2 - 10.1111/j.1753-4887.2011.00428.x

DO - 10.1111/j.1753-4887.2011.00428.x

M3 - Article

VL - 69

SP - S17-22

JO - Nutrition Research Reviews

JF - Nutrition Research Reviews

SN - 0954-4224

IS - Suppl 1

ER -