Single-cell genomics

Alan Walker, Julian Parkhill

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Efforts to describe and functionally categorize the amazing diversity of microbial life have long been hampered by our inability to cultivate most microorganisms in the laboratory. Recent technological advances in whole-genome amplification and cell sorting now permit insights into previously uncharacterized microorganisms, without prior cultivation. This month's Genome Watch reviews a selection of the initial attempts to exploit these important advances.
Original languageEnglish
Pages (from-to)176-177
Number of pages2
JournalNature Reviews Microbiology
Volume6
Issue number3
DOIs
Publication statusPublished - Mar 2008

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Keywords

  • bacteria
  • environmental microbiology
  • flow cytometry
  • genes, bacterial
  • genomics
  • humans
  • microfluidics
  • microscopy
  • mouth
  • nucleic acid amplification techniques
  • RNA, ribosomal, 16S
  • sensitivity and specificity

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