Systemic vasculitides: An overview

Dana Kidder, Paula Dospinescu, Maria Karabayas, Neil Basu

Research output: Contribution to journalArticle

Abstract

The systemic vasculitides are a group of uncommon but serious multisystem autoimmune disorders characterized by blood vessel inflammation. Timely diagnosis and intervention are crucial in preserving organ function and reducing mortality and morbidity. Immunosuppressive agents are the cornerstone of treatment and have revolutionized outcomes. Nevertheless, disease relapse is common, and individuals with vasculitides accumulate significant risks of infection, cardiovascular disease and malignancy over time compared with the general population, and invariably report poor quality of life. Toxicity from therapeutic agents - especially glucocorticoids - contributes to these complications.

Original languageEnglish
Pages (from-to)93-97
Number of pages5
JournalMedicine (United Kingdom)
Volume46
Issue number2
Early online date11 Jan 2018
DOIs
Publication statusPublished - Feb 2018

Keywords

  • Antineutrophil cytoplasmic antibody
  • Cryoglobulins
  • Giant cell arteritis
  • Granulomatosis with polyangiitis
  • Microscopic polyangiitis
  • MRCP
  • Polyarteritis nodosa

ASJC Scopus subject areas

  • Medicine(all)

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    Kidder, D., Dospinescu, P., Karabayas, M., & Basu, N. (2018). Systemic vasculitides: An overview. Medicine (United Kingdom), 46(2), 93-97. https://doi.org/10.1016/j.mpmed.2017.11.001