Abstract
The systemic vasculitides are a group of uncommon but serious multisystem autoimmune disorders characterized by blood vessel inflammation. Timely diagnosis and intervention are crucial in preserving organ function and reducing mortality and morbidity. Immunosuppressive agents are the cornerstone of treatment and have revolutionized outcomes. Nevertheless, disease relapse is common, and individuals with vasculitides accumulate significant risks of infection, cardiovascular disease and malignancy over time compared with the general population, and invariably report poor quality of life. Toxicity from therapeutic agents - especially glucocorticoids - contributes to these complications.
| Original language | English |
|---|---|
| Pages (from-to) | 93-97 |
| Number of pages | 5 |
| Journal | Medicine (United Kingdom) |
| Volume | 46 |
| Issue number | 2 |
| Early online date | 11 Jan 2018 |
| DOIs | |
| Publication status | Published - Feb 2018 |
Keywords
- Antineutrophil cytoplasmic antibody
- Cryoglobulins
- Giant cell arteritis
- Granulomatosis with polyangiitis
- Microscopic polyangiitis
- MRCP
- Polyarteritis nodosa
