Terfenadine and brompheniramine maleate in urticaria and dermographism

Anthony Ormerod, R Baker, J Watt, M I White

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The effects of brompheniramine maleate (12 mg twice daily in sustained release form) and terfenadine (60 mg twice daily) on the symptoms and well-being of 16 adults with urticaria with or without dermographism were assessed by symptom questionnaire. Following an initial 2-week period without therapy, each drug was taken for 2 weeks in a randomised double-blind cross-over study. Both drugs produced significant relief of itch and rash but only brompheniramine produced significant drowsiness. Brompheniramine maleate was more effective than terfenadine in the patients with dermographism.
Original languageEnglish
Pages (from-to)5-8
Number of pages4
JournalDermatologica
Volume173
Issue number1
DOIs
Publication statusPublished - 1 Jan 1986

Fingerprint

Brompheniramine
Terfenadine
Urticaria
Sleep Stages
Exanthema
Cross-Over Studies
Drug Therapy
Pharmaceutical Preparations

Keywords

  • Adult
  • Benzhydryl Compounds
  • Brompheniramine
  • Clinical Trials as Topic
  • Double-Blind Method
  • Histamine H1 Antagonists
  • Humans
  • Pyridines
  • Random Allocation
  • Terfenadine
  • Urticaria

Cite this

Terfenadine and brompheniramine maleate in urticaria and dermographism. / Ormerod, Anthony; Baker, R; Watt, J; White, M I.

In: Dermatologica, Vol. 173, No. 1, 01.01.1986, p. 5-8.

Research output: Contribution to journalArticle

Ormerod, A, Baker, R, Watt, J & White, MI 1986, 'Terfenadine and brompheniramine maleate in urticaria and dermographism', Dermatologica, vol. 173, no. 1, pp. 5-8. https://doi.org/10.1159/000249207
Ormerod, Anthony ; Baker, R ; Watt, J ; White, M I. / Terfenadine and brompheniramine maleate in urticaria and dermographism. In: Dermatologica. 1986 ; Vol. 173, No. 1. pp. 5-8.
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