Terfenadine and brompheniramine maleate in urticaria and dermographism

Anthony Ormerod, R Baker, J Watt, M I White

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10 Citations (Scopus)

Abstract

The effects of brompheniramine maleate (12 mg twice daily in sustained release form) and terfenadine (60 mg twice daily) on the symptoms and well-being of 16 adults with urticaria with or without dermographism were assessed by symptom questionnaire. Following an initial 2-week period without therapy, each drug was taken for 2 weeks in a randomised double-blind cross-over study. Both drugs produced significant relief of itch and rash but only brompheniramine produced significant drowsiness. Brompheniramine maleate was more effective than terfenadine in the patients with dermographism.
Original languageEnglish
Pages (from-to)5-8
Number of pages4
JournalDermatologica
Volume173
Issue number1
DOIs
Publication statusPublished - 1 Jan 1986

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Keywords

  • Adult
  • Benzhydryl Compounds
  • Brompheniramine
  • Clinical Trials as Topic
  • Double-Blind Method
  • Histamine H1 Antagonists
  • Humans
  • Pyridines
  • Random Allocation
  • Terfenadine
  • Urticaria

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