The relation between total cerebral small vessel disease burden and gait impairment in patients with minor stroke

C. M. Loos, C. McHutchison, V. Cvoro, S. D. Makin, J. Staals, F. Chappell, M.S. Dennis, R. J. van Oostenbrugge, J. M. Wardlaw

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Abstract

Background and aims Individual MRI markers of cerebral small vessel disease are associated with gait impairment. The impact of total cerebral small vessel disease-related brain damage, expressed by a cerebral small vessel disease MRI burden score, on mobility after stroke, has not been considered, although this score gives a better representation of the overall effect of cerebral small vessel disease on the brain. We determined if the total cerebral small vessel disease burden is associated with gait impairment three years after minor stroke. Methods In total, 200 patients with minor lacunar or non-lacunar stroke (NIHSS
Original languageEnglish
Pages (from-to)518-524
Number of pages7
JournalInternational Journal of Stroke
Volume13
Issue number5
Early online date1 Jul 2018
DOIs
Publication statusPublished - 2018

Keywords

  • Cerebal small vessel disease
  • minor stroke
  • total cerebal small vessel disease burden
  • gait impairment
  • stroke impact scale
  • functional outcome

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    Loos, C. M., McHutchison, C., Cvoro, V., Makin, S. D., Staals, J., Chappell, F., Dennis, M. S., van Oostenbrugge, R. J., & Wardlaw, J. M. (2018). The relation between total cerebral small vessel disease burden and gait impairment in patients with minor stroke. International Journal of Stroke, 13(5), 518-524. https://doi.org/10.1177/1747493017730780