The role of anti-Müllerian hormone assessment in assisted reproductive technology outcome

Simone L. Broer, Benwillem Mol, Madeleine Dólleman, Bart C. Fauser, Frank J.M. Broekmans

Research output: Contribution to journalReview article

93 Citations (Scopus)

Abstract

Purpose of review The purpose of this study is to summarize the role of anti-Müllerian hormone (AMH) in assisted reproductive technology (ART) treatment. Recent findings AMH is a good marker in the prediction of ovarian response to controlled ovarian hyperstimulation. In clinical practice, this means that AMH may be used for identifying poor or excessive responders. So far, studies show that AMH is not a good predictor for the occurrence of pregnancy after ART treatment. Therefore, routine screening for a poor ovarian reserve status using AMH is not to be advocated. Still, ovarian response prediction using AMH may open ways for patient-tailored stimulation protocols in order to reduce cancellations for excessive response, possibly improve pregnancy prospects and reduce costs. Summary AMH is able to predict extremes in ovarian response to controlled ovarian hyperstimulation but cannot predict pregnancy after ART treatment. Its future clinical role may be in the individualization of ART stimulation protocols.

Original languageEnglish
Pages (from-to)193-201
Number of pages9
JournalCurrent Opinion in Obstetrics and Gynecology
Volume22
Issue number3
DOIs
Publication statusPublished - Jun 2010

Keywords

  • Anti-Mudie;llerian hormone
  • Assisted reproductive technology
  • In-vitro fertilization
  • Intracytoplasmic sperm injection
  • Ovarian response

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