Urinary excretion of arsenic following rice consumption

A. A. Meharg*, P. N. Williams, C. M. Deacon, Gareth John Norton, Mohammed Kamal Hossain, D. Louhing, Ernest Melkiory Marwa, Y. Lawgalwi, Mark Antony Taggart, Claudia Cascio, P. Haris

*Corresponding author for this work

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Patterns of arsenic excretion were followed in a cohort (n = 6) eating a defined rice diet, 300 g per day d.wt. where arsenic speciation was characterized in cooked rice, following a period of abstinence from rice, and other high arsenic containing foods. A control group who did not consume rice were also monitored. The rice consumed in the study contained inorganic arsenic and dimethylarsinic acid (DMA) at a ratio of 1:1, yet the urine speciation was dominated by DMA (90%). At steady state (rice consumption/urinary excretion) ∼40% of rice derived arsenic was excreted via urine. By monitoring of each urine pass throughout the day it was observed that there was considerable variation (up to 13-fold) for an individual's total arsenic urine content, and that there was a time dependent variation in urinary total arsenic content. This calls into question the robustness of routinely used first pass/spot check urine sampling for arsenic analysis.

Original languageEnglish
Pages (from-to)181-187
Number of pages7
JournalEnvironmental Pollution
Volume194
Early online date19 Aug 2014
DOIs
Publication statusPublished - Nov 2014

Fingerprint

Arsenic
Urine
Cacodylic Acid
Nutrition
Acids
Oryza
Eating
Sampling
Diet
Food
Control Groups
Monitoring

Keywords

  • arsenic
  • rice
  • speciation
  • urine

ASJC Scopus subject areas

  • Pollution
  • Health, Toxicology and Mutagenesis
  • Toxicology
  • Medicine(all)

Cite this

Meharg, A. A., Williams, P. N., Deacon, C. M., Norton, G. J., Hossain, M. K., Louhing, D., ... Haris, P. (2014). Urinary excretion of arsenic following rice consumption. Environmental Pollution, 194, 181-187. https://doi.org/10.1016/j.envpol.2014.07.031

Urinary excretion of arsenic following rice consumption. / Meharg, A. A.; Williams, P. N.; Deacon, C. M.; Norton, Gareth John; Hossain, Mohammed Kamal; Louhing, D.; Marwa, Ernest Melkiory; Lawgalwi, Y.; Taggart, Mark Antony; Cascio, Claudia; Haris, P.

In: Environmental Pollution, Vol. 194, 11.2014, p. 181-187.

Research output: Contribution to journalArticle

Meharg, AA, Williams, PN, Deacon, CM, Norton, GJ, Hossain, MK, Louhing, D, Marwa, EM, Lawgalwi, Y, Taggart, MA, Cascio, C & Haris, P 2014, 'Urinary excretion of arsenic following rice consumption', Environmental Pollution, vol. 194, pp. 181-187. https://doi.org/10.1016/j.envpol.2014.07.031
Meharg AA, Williams PN, Deacon CM, Norton GJ, Hossain MK, Louhing D et al. Urinary excretion of arsenic following rice consumption. Environmental Pollution. 2014 Nov;194:181-187. https://doi.org/10.1016/j.envpol.2014.07.031
Meharg, A. A. ; Williams, P. N. ; Deacon, C. M. ; Norton, Gareth John ; Hossain, Mohammed Kamal ; Louhing, D. ; Marwa, Ernest Melkiory ; Lawgalwi, Y. ; Taggart, Mark Antony ; Cascio, Claudia ; Haris, P. / Urinary excretion of arsenic following rice consumption. In: Environmental Pollution. 2014 ; Vol. 194. pp. 181-187.
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