Urinary excretion of arsenic following rice consumption

A. A. Meharg*, P. N. Williams, C. M. Deacon, Gareth John Norton, Mohammed Kamal Hossain, D. Louhing, Ernest Melkiory Marwa, Y. Lawgalwi, Mark Antony Taggart, Claudia Cascio, P. Haris

*Corresponding author for this work

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Patterns of arsenic excretion were followed in a cohort (n = 6) eating a defined rice diet, 300 g per day d.wt. where arsenic speciation was characterized in cooked rice, following a period of abstinence from rice, and other high arsenic containing foods. A control group who did not consume rice were also monitored. The rice consumed in the study contained inorganic arsenic and dimethylarsinic acid (DMA) at a ratio of 1:1, yet the urine speciation was dominated by DMA (90%). At steady state (rice consumption/urinary excretion) ∼40% of rice derived arsenic was excreted via urine. By monitoring of each urine pass throughout the day it was observed that there was considerable variation (up to 13-fold) for an individual's total arsenic urine content, and that there was a time dependent variation in urinary total arsenic content. This calls into question the robustness of routinely used first pass/spot check urine sampling for arsenic analysis.

Original languageEnglish
Pages (from-to)181-187
Number of pages7
JournalEnvironmental Pollution
Volume194
Early online date19 Aug 2014
DOIs
Publication statusPublished - Nov 2014

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Keywords

  • arsenic
  • rice
  • speciation
  • urine

ASJC Scopus subject areas

  • Pollution
  • Health, Toxicology and Mutagenesis
  • Toxicology
  • Medicine(all)

Cite this

Meharg, A. A., Williams, P. N., Deacon, C. M., Norton, G. J., Hossain, M. K., Louhing, D., ... Haris, P. (2014). Urinary excretion of arsenic following rice consumption. Environmental Pollution, 194, 181-187. https://doi.org/10.1016/j.envpol.2014.07.031