We describe the syntheses and crystal structures of two indole derivatives, namely a second monoclnic polymorph of ethyl 5-chloro-1H-indole-2-carboxylate (I) and ethyl 5-chloro-3-iodo-1H-indole-2-carboxylate (II). In their crystal structures, both compounds form inversion dimers linked by pairs of N—H···O hydrogen bonds, which generate R2 2(10) loops. The dimers are linked into double chains in (I) and sheets in (II) by a variety of weak interactions, including π-π stacking, C—I···π, C—Cl—π interactions and I···Cl halogen bonds.
|Number of pages||5|
|Journal||Acta Crystallographica Section E: Crystallographic Communications|
|Publication status||Published - 1 Jul 2016|
- crystal structure
- N-H...O hydrogen bonds
- inversion dimers
- weak interactions