Research Output

2020

[18F]ZCDD083: a PFKFB3-targeted PET tracer for atherosclerotic plaque imaging

De Dominicis, C., Perrotta, P., Dall'angelo, S., Wyffels, L., Staelens, S., de Meyer, G. R. Y. & Zanda, M., 14 May 2020, In : ACS Medicinal Chemistry Letters. 11, 5, p. 933-939 7 p.

Research output: Contribution to journalArticle

Ablation of Bscl2/Seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

Mcilroy, G. D., Mitchell, S. E., Han, W., Delibegović, M. & Rochford, J. J., 17 Jan 2020, In : Disease Models & Mechanisms. 13, 1, 10 p., dmm042655.

Research output: Contribution to journalArticle

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A cell-based assay system for activators of the environmental cell stress response

Harbottle, J. A., Petrie, L., Ruhe, M., Houssen, W. E., Jaspars, M. & Kolb, A. F., 1 Mar 2020, In : Analytical Biochemistry. 592, 113583.

Research output: Contribution to journalArticle

A Circulating MicroRNA Profile in a Laser-Induced Mouse Model of Choroidal Neovascularization

Kiel, C., Berber, P., Karlstetter, M., Aslanidis, A., Strunz, T., Langmann, T., Grassmann, F. & Weber, B. H. F., Apr 2020, In : International Journal of Molecular Sciences. 21, 8, 2689.

Research output: Contribution to journalArticle

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2 Citations (Scopus)
1 Downloads (Pure)

Adolescent cannabis exposure increases heroin reinforcement in rats genetically vulnerable to addiction

Scifo, A., Lecca, D., Pisanu, A., Valentini, V., Piras, G., Sil, A., Cadoni, C. & Di Chiara, G., Apr 2020, In : Neuropharmacology. 166, 107974.

Research output: Contribution to journalArticle

A dot-stripe Turing model of joint patterning in the tetrapod limb

Scoones, J. C. & Hiscock, T. W., 12 Apr 2020, In : Development. 147, 8, 12 p., dev183699.

Research output: Contribution to journalArticle

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Analysing the impact of living in a rural setting on the presentation and outcome of colorectal cancer: A prospective single centre observational study

MacVicar, E., Ritchie, D., Murchie, P., Parnaby, C., MacKay, C. & Ramsay, G., 14 Mar 2020, In : The Surgeon.

Research output: Contribution to journalArticle

Anticancer effects of n-3 EPA and DHA and their endocannabinoid derivatives on breast cancer cell growth and invasion

Brown, I., Lee, J., Sneddon, A. A., Cascio, M. G., Pertwee, R. G., Wahle, K. W. J., Rotondo, D. & Heys, S. D., May 2020, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. 156, 10 p., 102024.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature

Leach, A., Smyth, P., Ferguson, L., Steven, J., Greene, M. K., Branco, C. M., McCann, A. P., Porter, A., Barelle, C. J. & Scott, C. J., 21 Jul 2020, In : Nanoscale. 12, 27, p. 14751-14763 13 p.

Research output: Contribution to journalArticle

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A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

International AMD Genomics Consortium (IAMDGC), 31 Jan 2020, In : Scientific Reports. 10, 16 p., 1584.

Research output: Contribution to journalArticle

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A Weakened Immune Response to Synthetic Exo-Peptides Predicts a Potential Biosecurity Risk in the Retrieval of Exo-Microorganisms

Schaefer, K., Dambuza, I. M., Dall'angelo, S., Trembleau, L., Zanda, M., Brown, G. D., Netea, M. G. & Gow, N. A. R., 17 Jul 2020, In : Microorganisms. 8, 7, 14 p., 1066.

Research output: Contribution to journalArticle

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BPA and risk assessment

Palmer, K. & Speirs, V., Apr 2020, In : The Lancet Diabetes and Endocrinology. 8, 4, p. 269 1 p.

Research output: Contribution to journalLetter

Calretinin is a novel candidate marker for adverse ovarian effects of early life exposure to mixtures of endocrine disruptors in the rat

Johansson, H. K. L., Svingen, T., Boberg, J., Fowler, P. A., Stead, D., Vinggaard, A. M. & Filis, P., Apr 2020, In : Archives of Toxicology. 94, p. 1241-1250 10 p.

Research output: Contribution to journalArticle

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1 Citation (Scopus)
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Candida auris: The path of yeast resistance

Lorenz, A., Apr 2020, In : Research Outreach. 113, p. 138-141 4 p.

Research output: Contribution to journalComment/debate

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Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s Disease and Frontotemporal Lobar Degeneration

Cranston, A. L., Wysocka, A., Steczkowska, M., Zadrozny, M., Palasz, E., Harrington, C. R., Theuring, F., Wischik, C., Riedel, G. & Niewiadomska, G., 2020, In : Brain Communications. 2, 1, 17 p., fcaa033.

Research output: Contribution to journalArticle

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Coagulation status of critically ill patients with and without liver disease assessed using a novel thrombin generation analyzer

Morrow, G. B., Beavis, J., Harper, S., Baker, P., Desbourough, M. J. R., Curry, N., Stanworth, S. J. & Laffan, M. A., Jul 2020, In : Journal of Thrombosis and Haemostasis. 18, 7, p. 1576-1585 10 p.

Research output: Contribution to journalArticle

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Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism

Abdelmoez, A. M., Puig, L. S., Smith, J. A. B., Gabriel, B. M., Savikj, M., Dollet, L., Chibalin, A. V., Krook, A., Zierath, J. R. & Pillon, N. J., Mar 2020, In : American Journal of Physiology: Cell Physiology. 318, 3, p. C615-C626 12 p.

Research output: Contribution to journalArticle

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5 Citations (Scopus)
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Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial

Liao, D. S., Grossi, F. V., El Mehdi, D., Gerber, M. R., Brown, D. M., Heier, J. S., Wykoff, C. C., Singerman, L. J., Abraham, P., Grassmann, F., Nuernberg, P., Weber, B. H. F., Deschatelets, P., Kim, R. Y., Chung, C. Y., Ribeiro, R. M., Hamdani, M., Rosenfeld, P. J., Boyer, D. S., Slakter, J. S. & 1 others, Francois, C. G., Feb 2020, In : Ophthalmology. 127, 2, p. 186-195 10 p.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
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Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia

Shiells, H., Schelter, B. O., Bentham, P., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Wischik, D. J., Riedel, G., Gauthier, S., Jia, J., Moebius, H. J., Hardlund, J., Kipps, C. M., Kook, K., Storey, J. M. D. & 2 others, Harrington, C. R. & Wischik, C. M., 19 May 2020, In : Journal of Alzheimer's Disease. 75, 2, p. 501-519 19 p.

Research output: Contribution to journalArticle

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1 Citation (Scopus)
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CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T-K. & MacKenzie, A., 13 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

CYP2D6 Genotype Predicts Tamoxifen Discontinuation and Prognosis in Patients With Breast Cancer

He, W., Grassmann, F., Eriksson, M., Eliasson, E., Margolin, S., Thorén, L., Hall, P. & Czene, K., 20 Feb 2020, In : Journal of Clinical Oncology. 38, 6, p. 548-557 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
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Delirium screening in the intensive care unit using emerging QEEG techniques: A pilot study

Hunter, A., Crouch, B., Webster, N. & Platt, B., 13 Jan 2020, In : AIMS Neuroscience. 7, 1, p. 1-16 16 p.

Research output: Contribution to journalArticle

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Dendrimer-coated carbon nanotubes deliver dsRNA and increase the efficacy of gene knockdown in the red flour beetle Tribolium castaneum

Edwards, C. H., Christie, C., Masotti, A., Celluzzi, A., Caporali, A. & Campbell, E. M., 24 Jul 2020, In : Scientific Reports. 10, 11 p., 12422.

Research output: Contribution to journalArticle

Open Access
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Dense active matter model of motion patterns in confluent cell monolayers

Henkes, S., Kostanjevec, K., Collinson, J. M., Sknepnek, R. & Bertin, E., 16 Mar 2020, In : Nature Communications. 11, 9 p., 1405.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
3 Downloads (Pure)

Design, synthesis, conjugation and reactivity of novel trans,trans-1,5-cyclooctadiene-derived bioorthogonal linkers

Longo, B., Zanato, C., Piras, M., Dall'angelo, S., Windhorst, A. D., Vugts, D., Baldassarre, M. & Zanda, M., 30 Jul 2020, In : Bioconjugate Chemistry.

Research output: Contribution to journalArticle

Design, synthesis, radiosynthesis and biological evaluation of Fenretinide analogues as anticancer and metabolic syndromepreventive agents

Zanda, M., Patruno, I., Thompson, D., Dall'angelo, S., Windhorst, A. D., Vugts, D. J., Poot, A. J. & Mody, N., 9 Jul 2020, In : ChemMedChem. 13 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
6 Downloads (Pure)
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Diverse LEF/TCF Expression in Human Colorectal Cancer Correlates with Altered Wnt-Regulated Transcriptome in a Meta-Analysis of Patient Biopsies

Mayer, C-D., de La Giclais, S. M., Alsehly, F. & Hoppler, S., May 2020, In : Genes. 11, 5, 23 p., 538.

Research output: Contribution to journalArticle

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Diversity and Global Distribution of Viruses of the Western Honey Bee, Apis mellifera

Beaurepaire, A., Piot, N., Doublet, V., Antunez, K., Campbell, E., Chantawannakul, P., Chejanovsky, N., Gajda, A., Heerman, M., Panziera, D., Smagghe, G., Yañez, O., de Miranda, J. R. & Dalmon, A., 10 Apr 2020, In : Insects. 11, 4, 25 p., 239.

Research output: Contribution to journalArticle

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3 Citations (Scopus)
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Downsizing Class II Lasso Peptides: Genome Mining-Guided Isolation of Huascopeptin Containing the First Gly1-Asp7 Macrocycle

Cortés-Albayay, C., Jarmusch, S. A., Trusch, F., Ebel, R., Andrews, B. A., Jaspars, M. & Asenjo, J. A., 7 Feb 2020, In : Journal of Organic Chemistry. 85, 3, p. 1661-1667 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Dynamics of the transcriptional landscape during human fetal testis and ovary development

Lecluze, E., Rolland, A. D., Filis, P., Evrard, B., Leverrier-Penna, S., Ben Maamar, M., Coiffec, I., Lavoué, V., Fowler, P. A., Mazaud Guittot, S., Jégou, B. & Chalmel, F., May 2020, In : Human Reproduction. 35, 5, p. 1099-1119 21 p.

Research output: Contribution to journalArticle

Effects of transcranial photobiomodulation and methylene blue on biochemical and behavioral profiles in mice stress model

Meynaghizadeh-Zargar, R., Sadigh-Eteghad, S., Mohaddes, G., Salehpour, F. & Rasta, S. H., Apr 2020, In : Lasers in Medical Science. 35, p. 573-584 12 p.

Research output: Contribution to journalArticle

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Efficacy of daratumumab combination regimen in patients with multiple myeloma: A combined analysis of phase III randomized controlled trials

Htut, T. W., Thein, K. Z., Lawrie, A., Tighe, J. & Preston, G., 23 Jun 2020, In : eJHaem.

Research output: Contribution to journalArticle

Open Access

Endocytic Sorting and Downregulation of the M2 Acetylcholine Receptor is Regulated by Ubiquitin and the ESCRT Complex

Zenko, D., Thompson, D. & Hislop, J. N., 1 Jan 2020, In : Neuropharmacology. 162, p. 107828 13 p., 107828.

Research output: Contribution to journalArticle

Endogenous IL-33 and Its Autoamplification of IL-33/ST2 Pathway Play an Important Role in Asthma

Magat, J. M., Thomas, J. L., Dumouchel, J. P., Murray, F., Li, W. X. & Li, J., 15 Mar 2020, In : The Journal of Immunology. 204, 6, p. 1592-1597 6 p.

Research output: Contribution to journalArticle

Epitope shaving promotes fungal immune evasion

Childers, D., Mol Avelar, G., Bain, J., Pradhan, A., Larcombe, D. E., Netea, M. G., Erwig, L. P., Gow, N. A. R. & Brown, A. J. P., Jul 2020, In : mBio. 11, 4, 13 p., e00984-20.

Research output: Contribution to journalArticle

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Expression of the Insulin-like Growth Factor system in first and second trimester human embryonic and fetal gonads

Mamsen, L. S., Zafeiri, A., Bøtkjær, J. A., Rasmussen, J. H., Ernst, E., Oxvig, C., Fowler, P. A. & Andersen, C. Y., 29 Jul 2020, In : Journal of Clinical Endocrinology and Metabolism.

Research output: Contribution to journalArticle

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14 Citations (Scopus)
1 Downloads (Pure)

Foxh1/Nodal defines context-specific direct maternal Wnt/β-catenin target gene regulation in early development

Afouda, B., Nakamura, Y., Shaw, S., Charney, R. M., Paraiso, K. D., Blitz, I. L., Cho, K. W. Y. & Hoppler, S., 24 Jul 2020, In : iScience. 23, 7, 34 p., 101314.

Research output: Contribution to journalArticle

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Geometric description for the anatomy of the mitral valve: A review

Oliveira, D., Srinivasan, J., Espino, D., Buchan, K., Dawson, D. & Shepherd, D., 3 Apr 2020, In : Journal of Anatomy. 237, 2, p. 209-224 16 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Green Bees: Reverse Genetic Analysis of Deformed Wing Virus Transmission, Replication, and Tropism

Gusachenko, O. N., Woodford, L., Balbirnie-Cumming, K., Campbell, E. M., Christie, C. R., Bowman, A. S. & Evans, D. J., May 2020, In : Viruses. 12, 5, 17 p., 532.

Research output: Contribution to journalArticle

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Host and pathogen autophagy are central to the inducible local defences and systemic response of the giant kelp Macrocystis pyrifera against the oomycete pathogen Anisolpidium ectocarpii

Murua, P., Müller, D. G., Etemadi, M., van West, P. & Gachon, C. M. M., Jun 2020, In : New Phytologist. 226, 5, p. 1445-1460 16 p.

Research output: Contribution to journalArticle

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Hydrogen bonding and the design of twist-bend nematogens

Walker, R., Pociecha, D., Crawford, C. A., Storey, J. M. D., Gorecka, E. & Imrie, C. T., Apr 2020, In : Journal of molecular liquids. 303, 9 p., 112630.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Hypoxia PET/CT and Colorectal Cancer: A Case Report

Laws, K., Zanda, M., Dall'angelo, S., McKiddie, F., Kerr, K., Murray, G. I., Fleming, I. & Samuel, L., 29 Jul 2020, (Accepted/In press) In : Journal of Case Reports and Images in Oncology.

Research output: Contribution to journalArticle