Research Output

2020

[18F]ZCDD083: a PFKFB3-targeted PET tracer for atherosclerotic plaque imaging

De Dominicis, C., Perrotta, P., Dall'angelo, S., Wyffels, L., Staelens, S., de Meyer, G. R. Y. & Zanda, M., 24 Feb 2020, In : ACS Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Open Access

Ablation of Bscl2/Seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

Mcilroy, G. D., Mitchell, S. E., Han, W., Delibegović, M. & Rochford, J. J., 17 Jan 2020, In : Disease Models & Mechanisms. 13, 1, 10 p., dmm042655.

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A cell-based assay system for activators of the environmental cell stress response

Harbottle, J. A., Petrie, L., Ruhe, M., Houssen, W. E., Jaspars, M. & Kolb, A. F., 1 Mar 2020, In : Analytical Biochemistry. 592, 113583.

Research output: Contribution to journalArticle

Analysing the impact of living in a rural setting on the presentation and outcome of colorectal cancer: A prospective single centre observational study

MacVicar, E., Ritchie, D., Murchie, P., Parnaby, C., MacKay, C. & Ramsay, G., 14 Mar 2020, In : The Surgeon.

Research output: Contribution to journalArticle

Calretinin is a novel candidate marker for adverse ovarian effects of early life exposure to mixtures of endocrine disruptors in the rat

Johansson, H. K. L., Svingen, T., Boberg, J., Fowler, P. A., Stead, D., Vinggaard, A. M. & Filis, P., 27 Mar 2020, In : Archives of Toxicology. 10 p.

Research output: Contribution to journalArticle

Open Access

Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s Disease and Frontotemporal Lobar Degeneration

Cranston, A. L., Wysocka, A., Steczkowska, M., Zadrozny, M., Palasz, E., Harrington, C. R., Theuring, F., Wischik, C., Riedel, G. & Niewiadomska, G., 3 Feb 2020, (Accepted/In press) In : Brain Communications.

Research output: Contribution to journalArticle

Concentration-dependent activity of hydromethylthionine on clinical decline and brain atrophy in a randomized controlled trial in behavioural variant frontotemporal dementia (bvFTD)

Shiells, H., Schelter, B. O., Bentham, P., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Wischik, D. J., Riedel, G., Gauthier, S., Jia, J., Moebius, H. J., Hardlund, J., Kipps, C. M., Kook, K., Storey, J. M. D. & 2 others, Harrington, C. R. & Wischik, C. M., 4 Mar 2020, (Accepted/In press) In : Journal of Alzheimer's Disease.

Research output: Contribution to journalArticle

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T-K. & MacKenzie, A., 13 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

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Delirium screening in the intensive care unit using emerging QEEG techniques: A pilot study

Hunter, A., Crouch, B., Webster, N. & Platt, B., 13 Jan 2020, In : AIMS Neuroscience. 7, 1, p. 1-16 16 p.

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Dense active matter model of motion patterns in confluent cell monolayers

Henkes, S., Kostanjevec, K., Collinson, J. M., Sknepnek, R. & Bertin, E., 16 Mar 2020, In : Nature Communications. 11, 1405.

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Downsizing Class II Lasso Peptides: Genome Mining-Guided Isolation of Huascopeptin Containing the First Gly1-Asp7 Macrocycle

Cortés-Albayay, C., Jarmusch, S. A., Trusch, F., Ebel, R., Andrews, B. A., Jaspars, M. & Asenjo, J. A., 7 Feb 2020, In : Journal of Organic Chemistry. 85, 3, p. 1661-1667 7 p.

Research output: Contribution to journalArticle

Endocytic Sorting and Downregulation of the M2 Acetylcholine Receptor is Regulated by Ubiquitin and the ESCRT Complex

Zenko, D., Thompson, D. & Hislop, J. N., 1 Jan 2020, In : Neuropharmacology. 162, p. 107828 13 p., 107828.

Research output: Contribution to journalArticle

Endogenous IL-33 and Its Autoamplification of IL-33/ST2 Pathway Play an Important Role in Asthma

Magat, J. M., Thomas, J. L., Dumouchel, J. P., Murray, F., Li, W. X. & Li, J., 15 Mar 2020, In : The Journal of Immunology. 204, 6, p. 1592-1597 6 p.

Research output: Contribution to journalArticle

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Ifu5, a WW domain-containing protein interacts with Efg1 to achieve coordination of normoxic and hypoxic functions to influence pathogenicity traits in Candida albicans

Rastogi, S. K., van Wijlick, L., Ror, S., Lee, K. K., Román, E., Agarwal, P., Manzoor, N., Gow, N. A. R., Pla, J., Ernst, J. F. & Panwar, S. L., Feb 2020, In : Cellular Microbiology. 22, 2, 15 p., e13140.

Research output: Contribution to journalArticle

Incidence of male breast cancer in Scotland over a twenty-five-year period (1992 - 2017)

Reddington, R., Galer, M., Hagedorn, A., Liu, P., Barrack, S., Husain, E., Sharma, R., Speirs, V. & Masannat, Y., 8 Jan 2020, In : European Journal of Surgical Oncology.

Research output: Contribution to journalArticle

Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans

Ntessalen, M., Procter, N. E., Schwarz, K., Loudon, B. L., Minnion, M., Fernandez, B. O., Vassiliou, V. S., Vauzour, D., Madhani, M., Constantin-Teodosiu, D., Horowitz, J. D., Feelisch, M., Dawson, D., Crichton, P. G. & Frenneaux, M. P., Jan 2020, In : The American Journal of Clinical Nutrition. 111, 1, p. 79-89 11 p.

Research output: Contribution to journalArticle

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Intragenic meiotic recombination in Schizosaccharomyces pombe is sensitive to environmental temperature changes

Brown, S. D., Audoynaud, C. & Lorenz, A., 1 Apr 2020, (Accepted/In press) In : Chromosome Research.

Research output: Contribution to journalArticle

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Klotho gene polymorphism, brain structure and cognition in early-life development

de Vries, C. F., Staff, R., Noble, K. G., Muetzel, R. L., Vernooij, M. W., White, T., Waiter, G. D. & Murray, A. D., 2020, In : Brain Imaging and Behavior. 14, p. 213-225 13 p.

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Knock-in of Mutated hTAU Causes Insulin Resistance, Inflammation and Proteostasis Disturbance in a Mouse Model of Frontotemporal Dementia

Hull, C., Dekeryte, R., Koss, D. J., Crouch, B., Buchanan, H., Delibegovic, M. & Platt, B., Jan 2020, In : Molecular Neurobiology. 57, 1, p. 539-550 12 p.

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Lights and shadows of schizophrenia therapy research: Lessons from oral risperidone and olanzapine

Nicotra, E. F., Lecca, D., Casu, G., Palomba, M., Sil, A. & Marchese, G., 21 Jan 2020, In : Journal of Psychopharmacology.

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Motion during Acquisition is Associated with fMRI Brain Entropy

de Vries, C., Staff, R. T., Waiter, G. D., Sokunbi, M. O., Sandu, A. L. & Murray, A. D., Feb 2020, In : IEEE journal of biomedical and health informatics. 24, 2, p. 586-593 8 p.

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Motor development in infancy and spine shape in early old age: findings from a British birth cohort study

Saunders, F. R., Gregory, J. S., Pavlova, A., Muthuri, S. G., Hardy, R. J., Martin, K. R., Barr, R. J., Adams, J. E., Kuh, D., Aspden, R. M., Cooper, R. & Ireland, A., 18 Mar 2020, In : Journal of Orthopaedic Research. 9 p.

Research output: Contribution to journalArticle

Open Access

Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation

Sim, M. F. M., Persiani, E., Talukder, M. M. U., McIlroy, G., Roumane, A., Edwardson, J. M. & Rochford, J., 24 Feb 2020, In : Scientific Reports. 10, 3259.

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Palmitic acid triggers inflammatory responses in N42 cultured hypothalamic cells partially via ceramide synthesis but not via TLR4

Sergi, D., Morris, A. C., Kahn, D. E., McLean, F. H., Hay, E. A., Kubitz, P., MacKenzie, A., Martinoli, M. G., Drew, J. E. & Williams, L. M., 2020, In : Nutritional Neuroscience. 23, 4, p. 321-334 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Positional Information – a concept underpinning our understanding of developmental biology

Vargesson, N., 1 Mar 2020, In : Developmental Dynamics. 249, 3, p. 298-312 15 p.

Research output: Contribution to journalArticle

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Pseudohyphal growth of the emerging pathogen Candida auris is triggered by genotoxic stress through the S phase checkpoint

Bravo Ruiz, G., Ross, Z. K., Gow, N. A. R. & Lorenz, A., 11 Mar 2020, In : mSphere. 5, 2, 17 p., e00151-20.

Research output: Contribution to journalArticle

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Regulation of Gdf5 expression in joint remodelling, repair and osteoarthritis

Kania, K., Colella, F., Riemen, A. H. K., Wang, H., Howard, K. A., Aigner, T., Dell'Accio, F., Capellini, T. D., Roelofs, A. J. & de Bari, C., 13 Jan 2020, In : Scientific Reports. 10, 157.

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Structure‐based design, synthesis and bioactivity of a new anti‐TNFα cyclopeptide

Idress, M., Milne, B. F., Thompson, G. S., Trembleau, L., Jaspars, M. & Houssen, W. E., 19 Feb 2020, In : Molecules. 25, 4, 922.

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The interoceptive hippocampus: Mouse brain endocrine receptor expression highlights a dentate gyrus (DG)-cornu ammonis (CA) challenge-sufficiency axis

Lathe, R., Singadia, S., Jordan, C. & Riedel, G., 15 Jan 2020, In : PloS ONE. 15, 1, e0227575.

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The molecular aetiology of tRNA synthetase depletion: induction of a GCN4 amino acid starvation response despite homeostatic maintenance of charged tRNA levels

McFarland, M. R., Keller, C. D., Childers, B. M., Adeniyi, S. A., Corrigall, H., Raguin, A., Romano, M. C. & Stansfield, I., 6 Apr 2020, In : Nucleic Acids Research. 48, 6, p. 3071-3088 18 p.

Research output: Contribution to journalArticle

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Toward a better understanding of the effects of endocrine disrupting compounds on health: Human-relevant case studies from sheep models

Viguié, C., Chaillou, E., Gayrard, V., Picard-Hagen, N. & Fowler, P. A., 5 Apr 2020, In : Molecular and Cellular Endocrinology. 505, 110711.

Research output: Contribution to journalReview article

Twist-Bend Nematogenic Supramolecular Dimers and Trimers Formed by Hydrogen Bonding

Walker, R., Pociecha, D., Martinez-Felipe, A., Storey, J. MD., Gorecka, E. & Imrie, C. T., 6 Mar 2020, In : Crystals. 10, 3, 175.

Research output: Contribution to journalArticle

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UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: questionnaire and workshop proceedings

McFall, A., Hietamies, T. M., Bernard, A., Aimable, M., Allan, S. M., Bath, P. M., Brezzo, G., Carare, R. O., Carswell, H. V., Clarkson, A. N., Currie, G., Farr, T. D., Fowler, J., Good, M., Hainsworth, A. H., Hall, C., Horsburgh, K., Kalaria, R., Kehoe, P., Lawrence, C. & 17 others, Macleod, M., McNeilly, A., Miller, A. A., Miners, S., Mok, V., O’Sullivan, M., Platt, B., Sena, E. S., Sharp, M., Strangeward, P., Szymkowiak, S., Touyz, R. M., Trueman, R. C., White, C., McCabe, C., Work, L. M. & Quinn, T. J., 9 Mar 2020, In : Journal of Cerebral Blood Flow and Metabolism.

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Young-onset colorectal cancer in the North East of Scotland: survival, clinico- pathological features and genetics

Perrott, S., Laurie, K., Laws, K., Johnes, A., Miedzybrodzka, Z. & Samuel, L., 10 Feb 2020, In : BMC Cancer. 20, 108.

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β-glucan is a major growth substrate for human gut bacteria related to Coprococcus eutactus

Alessi, A. M., Gray, V., Farquharson, F. M., Louis, P., Flores-López, A., Shaw, S., Stead, D., Wegmann, U., Shearman, C., Gasson, M., Collie-Duguid, E. SR., Flint, H. J. & Louis, P., 20 Mar 2020, In : Environmental Microbiology.

Research output: Contribution to journalArticle

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2019

27 years of prenatal diagnosis for Huntington disease in the United Kingdom

Piña-Aguilar, R. E., Simpson, S. A., Alshatti, A., Clarke, A., Craufurd, D., Dorkins, H., Doye, K., Lahiri, N., Lashwood, A., Lynch, C., Miller, C., Morton, S., O’Driscoll, M., Quarrell, O. W., Rae, D., Strong, M., Tomlinson, C., Turnpenny, P., Miedzybrodzka, Z. & UK HD Predictive Testing Consortium, Jul 2019, In : Genetics in Medicine. 21, p. 1639–1643 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

ABC Transporter Genes Show Upregulated Expression in Drug Resistant Clinical Isolates of Candida auris: a Genome-Wide Characterization of ATP-Binding Cassette (ABC) Transporter Genes

Wasi, M., Khandelwal, N. K., Moorhouse, A. J., Nair, R., Vishwakarma, P., Ruiz, G. B., Ross, Z. K., Lorenz, A., Rudramurthy, S. M., Chakrabarti, A., Lynn, A. M., Mondal, A. K., Gow, N. A. R. & Prasad, R., 16 Jul 2019, In : Frontiers in Microbiology. 10, 16 p., 1445.

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A Bioluminescence Reporter Assay for Retinoic Acid Control of Translation of the GluR1 Subunit of the AMPA Glutamate Receptor

Khatib, T., Whiting, A., Chisholm, D. R., Redfern, C., Muller, B. & McCaffery, P., Oct 2019, In : Molecular Neurobiology. 56, 10, p. 7074-7084 11 p.

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