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19972019
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Research Output 1997 2019

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Article
2019

Immunostaining of Skeletal Tissues

Roelofs, A. J. & De Bari, C., 8 Feb 2019, In : Methods in molecular biology (Clifton, N.J.). 1914, p. 437-450 14 p.

Research output: Contribution to journalArticle

Cryoultramicrotomy
Immunohistochemistry
Paraffin Embedding
Antigens
Translational Medical Research
2018
2 Citations (Scopus)
9 Downloads (Pure)

Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease

McIlroy, G. D., Suchacki, K., Roelofs, A. J., Yang, W., Fu, Y., Bai, B., Wallace, R. J., de Bari, C., Cawthorn, W. P., Han, W., Delibegovic, M. & Rochford, J. J., Apr 2018, In : Molecular Metabolism. 10, p. 55-65 11 p.

Research output: Contribution to journalArticle

Open Access
File
Congenital Generalized Lipodystrophy
Metabolic Diseases
Adipocytes
High Fat Diet
Lipodystrophy
2017
24 Citations (Scopus)
8 Downloads (Pure)

Joint morphogenetic cells in the adult mammalian synovium

Roelofs, A. J., Zupan, J., Riemen, A. H. K., Kania, K., Ansboro, S., White, N., Clark, S. M. & De Bari, C., 16 May 2017, In : Nature Communications. 8, 15040 .

Research output: Contribution to journalArticle

Open Access
File
Synovial Membrane
stem cells
Stem cells
Mesenchymal Stromal Cells
Joints
2016
3 Citations (Scopus)
6 Downloads (Pure)

Bone Marrow Contribution to Synovial Hyperplasia Following Joint Surface Injury

Sergijenko, A., Roelofs, A. J., Riemen, A. H. K. & De Bari, C., 13 Jul 2016, In : Arthritis Research & Therapy. 18, p. 1-11 11 p., 166.

Research output: Contribution to journalArticle

Open Access
File
Hyperplasia
Mesenchymal Stromal Cells
Joints
Bone Marrow
Green Fluorescent Proteins
11 Citations (Scopus)
6 Downloads (Pure)

MICL controls inflammation in rheumatoid arthritis

Redelinghuys, P., Whitehead, L., Augello, A., Drummond, R. A., Levesque, J-M., Vautier, S., Reid, D. M., Kerscher, B., Taylor, J. A., Nigrovic, P. A., Wright, J., Murray, G. I., Willment, J. A., Hocking, L. J., Fernandes, M. J. G., De Bari, C., McInnes, I. B. & Brown, G. D., Jul 2016, In : Annals of the Rheumatic Diseases. 75, 7, p. 1386-1391 6 p.

Research output: Contribution to journalArticle

Open Access
File
C-Type Lectins
Rheumatoid Arthritis
Inflammation
Myeloid Cells
Antibodies
2015
33 Citations (Scopus)
5 Downloads (Pure)

A homeostatic function of CXCR2 signalling in articular cartilage

Sherwood, J., Bertrand, J., Nalesso, G., Poulet, B., Pitsillides, A., Brandolini, L., Karystinou, A., De Bari, C., Luyten, F. P., Pitzalis, C., Pap, T. & Dell'Accio, F., 2015, In : Annals of the Rheumatic Diseases. 74, 12, p. 2207-2215 9 p.

Research output: Contribution to journalArticle

Open Access
File
Cartilage
Articular Cartilage
Chondrocytes
CXC Chemokines
Apoptosis
25 Citations (Scopus)

Homing of mesenchymal stem cells: mechanistic or stochastic? Implications for targeted delivery in arthritis

Eseonu, O. I. & De Bari, C., 1 Feb 2015, In : Rheumatology. 54, 2, p. 210-218 9 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Arthritis
Cell- and Tissue-Based Therapy
Cartilage
Articular Cartilage
30 Citations (Scopus)
7 Downloads (Pure)

Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells

Karystinou, A., Roelofs, A. J., Neve, A., Cantatore, F. P., Wackerhage, H. & De Bari, C., 30 May 2015, In : Arthritis Research & Therapy. 17, 14 p., 147.

Research output: Contribution to journalArticle

Open Access
File
Chondrogenesis
Mesenchymal Stromal Cells
Proteins
Bone Morphogenetic Protein 2
Down-Regulation
2014
5 Citations (Scopus)

Articular Chondroprogenitor Cells Maintain Chondrogenic Potential but Fail to Form a Functional Matrix When Implanted Into Muscles of SCID Mice

Marcus, P., De Bari, C., Dell'Accio, F. & Archer, C. W., Oct 2014, In : Cartilage. 5, 4, p. 231-240 10 p.

Research output: Contribution to journalArticle

SCID Mice
Cartilage
Articular Cartilage
Collagen Type II
Muscle
4 Citations (Scopus)
4 Downloads (Pure)

In vivo phenotypic characterisation of nucleoside label-retaining cells in mouse periosteum

Cherry, H. M., Roelofs, A. J., Kurth, T. & De Bari, C., 11 Mar 2014, In : European Cells & Materials. 27, p. 185-195 11 p.

Research output: Contribution to journalArticle

Open Access
File
76 Citations (Scopus)

The Hippo Transducer YAP1 Transforms Activated Satellite Cells and Is a Potent Effector of Embryonal Rhabdomyosarcoma Formation

Tremblay, A. M., Missiaglia, E., Galli, G. G., Hettmer, S., Urcia, R., Carrara, M., Judson, R. N., Thway, K., Nadal, G., Selfe, J. L., Murray, G. I., Calogero, R. A., De Bari, C., Zammit, P. S., Delorenzi, M., Wagers, A. J., Shipley, J., Wackerhage, H. & Camargo, F. D., 11 Aug 2014, In : Cancer Cell. 26, 2, p. 273-287 15 p.

Research output: Contribution to journalArticle

2013

Mesenchymal stem cell niches in joint health and disease

De Bari, C., 2013, In : European Cells & Materials. 26, suppl. 3, p. 5 1 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Prospective purification of a subpopulation of human synovial mesenchymal stem cells with enhanced chondro-osteogenic potency.

Gullo, F. & De Bari, C., Oct 2013, In : Rheumatology. 52, 10, p. 1758-1768 11 p.

Research output: Contribution to journalArticle

Open Access
Mesenchymal Stromal Cells
Synovial Membrane
Population
Cell Aging
Flow Cytometry
2012
2 Citations (Scopus)

Immunostaining of skeletal tissues

Kurth, T. B. & De Bari, C., 2012, In : Methods in Molecular Biology. 816, 4, p. 321-334 14 p.

Research output: Contribution to journalArticle

File
Immunohistochemistry
Paraffin Embedding
Antigens
Waxes
Paraffin
67 Citations (Scopus)

The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells

Judson, R. N., Tremblay, A. M., Knopp, P., White, R. B., Urcia, R., De Bari, C., Zammit, P. S., Camargo, F. D. & Wackerhage, H., 15 Dec 2012, In : Journal of Cell Science. 125, 24, p. 6009-6019 11 p.

Research output: Contribution to journalArticle

Muscle Cells
Myoblasts
Stem Cells
Gene Expression
Muscles
2011
57 Citations (Scopus)

Directed migration of human bone marrow mesenchymal stem cells in a physiological direct current electric field

Zhao, Z., Watt, C., Karystinou, A., Roelofs, A. J., McCaig, C. D., Gibson, I. R. & De Bari, C., 29 Nov 2011, In : European Cells & Materials. 22, -, p. 344-358 15 p., -.

Research output: Contribution to journalArticle

Stem cells
Mesenchymal Stromal Cells
Bone
Bone Marrow
Electric fields
228 Citations (Scopus)

Dual origin of mesenchymal stem cells contributing to organ growth and repair

Feng, J., Mantesso, A., De Bari, C., Nishiyama, A. & Sharpe, P. T., 19 Apr 2011, In : PNAS. 108, 16, p. 6503-6508 6 p.

Research output: Contribution to journalArticle

Pericytes
Mesenchymal Stromal Cells
Odontoblasts
Growth
Tooth
112 Citations (Scopus)

Functional mesenchymal stem cell niches in adult mouse knee joint synovium in vivo

Kurth, T. B., Dell'Accio, F., Crouch, V., Augello, A., Sharpe, P. T. & De Bari, C., May 2011, In : Arthritis & Rheumatism. 63, 5, p. 1289-1300 12 p.

Research output: Contribution to journalArticle

Stem Cell Niche
Synovial Membrane
Knee Joint
Mesenchymal Stromal Cells
Nucleosides
47 Citations (Scopus)

Future dentistry: cell therapy meets tooth and periodontal repair and regeneration

Catón, J., Bostanci, N., Remboutsika, E., De Bari, C. & Mitsiadis, T. A., May 2011, In : Journal of Cellular and Molecular Medicine. 15, 5, p. 1054-1065 12 p.

Research output: Contribution to journalArticle

Cell- and Tissue-Based Therapy
Dentistry
Regeneration
Tooth
Stem Cells
4 Citations (Scopus)

Mesenchymal differentiation propensity of a human embryonic stem cell line

Pringle, S., De Bari, C., Dell'accio, F., Przyborski, S., Cooke, M. J., Minger, S. L. & Grigoriadis, A. E., 1 Apr 2011, In : Cell Proliferation. 44, 2, p. 120-127 8 p.

Research output: Contribution to journalArticle

Embryoid Bodies
Cell Line
Germ Layers
SCID Mice
Teratoma
34 Citations (Scopus)

Prospects of stem cell therapy in osteoarthritis

Roberts, S., Genever, P., McCaskie, A. & De Bari, C., 2011, In : Regenerative Medicine. 6, 3, p. 351-366 16 p.

Research output: Contribution to journalArticle

Cell- and Tissue-Based Therapy
Stem cells
Osteoarthritis
Stem Cells
Joints
60 Citations (Scopus)

Role of mesenchymal stem cells in reestablishing immunologic tolerance in autoimmune rheumatic diseases

MacDonald, G. I. A., Augello, A. & De Bari, C., Sep 2011, In : Arthritis & Rheumatism. 63, 9, p. 2547-2557 11 p.

Research output: Contribution to journalArticle

108 Citations (Scopus)
6 Downloads (Pure)

WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways

Nalesso, G., Sherwood, J., Bertrand, J., Pap, T., Ramachandran, M., De Bari, C., Pitzalis, C. & Dell'accio, F., May 2011, In : Journal of Cell Biology. 193, 3, p. 551-564 14 p.

Research output: Contribution to journalArticle

Open Access
File
Catenins
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Chondrocytes
Joints
Phenotype
2010
27 Citations (Scopus)

Human single-chain variable fragment that specifically targets arthritic cartilage

Hughes, C., Faurholm, B., Dell'Accio, F., Manzo, A., Seed, M., Eltawil, N., Marrelli, A., Gould, D., Subang, C., Al-Kashi, A., De Bari, C., Winyard, P., Chernajovsky, Y. & Nissim, A., Apr 2010, In : Arthritis & Rheumatism. 62, 4, p. 1007-1016 10 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Arthritis
Cartilage
Tumor Necrosis Factor Receptors
Joints
214 Citations (Scopus)

Mesenchymal stem cells: a perspective from in vitro cultures to in vivo migration and niches

Augello, A., Kurth, T. B. & De Bari, C., 1 Sep 2010, In : European Cells & Materials. 20, p. 121-133 13 p.

Research output: Contribution to journalArticle

Stem cells
Mesenchymal Stromal Cells
Cell culture
Stem Cells
Stromal Cells
28 Citations (Scopus)

Mesenchymal stem cells from development to postnatal joint homeostasis, aging, and disease

De Bari, C., Kurth, T. B. & Augello, A., Dec 2010, In : Birth Defects Research. Part C, Embryo Today: Reviews. 90, 4, p. 257-271 15 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Homeostasis
Joints
Stem Cell Niche
Regenerative Medicine
206 Citations (Scopus)
4 Downloads (Pure)

The regulation of differentiation in mesenchymal stem cells

Augello, A. & De Bari, C., 1 Oct 2010, In : Human Gene Therapy. 21, 10, p. 1226-1238 13 p.

Research output: Contribution to journalArticle

Open Access
File
Mesenchymal Stromal Cells
Cell Differentiation
Cartilage
Stem Cell Niche
Chondrogenesis
105 Citations (Scopus)

Toward cell therapy using placenta-derived cells: disease mechanisms, cell biology, preclinical studies, and regulatory aspects at the round table

Parolini, O., Alviano, F., Bergwerf, I., Boraschi, D., De Bari, C., De Waele, P., Dominici, M., Evangelista, M., Falk, W., Hennerbichler, S., Hess, D. C., Lanzoni, G., Liu, B., Marongiu, F., McGuckin, C., Mohr, S., Nolli, M. L., Ofir, R., Ponsaerts, P., Romagnoli, L. & 10 othersSolomon, A., Soncini, M., Strom, S., Surbek, D., Venkatachalam, S., Wolbank, S., Zeisberger, S., Zeitlin, A., Zisch, A. & Borlongan, C. V., 25 Feb 2010, In : Stem Cells and Development. 19, 2, p. 143-154 12 p.

Research output: Contribution to journalArticle

Cell- and Tissue-Based Therapy
Placenta
Cell Biology
Stem Cells
Regenerative Medicine
67 Citations (Scopus)

Yap is a novel regulator of C2C12 myogenesis

Watt, K. I., Judson, R., Medlow, P., Reid, K., Kurth, T. B., Burniston, J. G., Ratkevicius, A., De Bari, C. & Wackerhage, H., 19 Mar 2010, In : Biochemical and Biophysical Research Communications. 393, 4, p. 619-624 6 p.

Research output: Contribution to journalArticle

Phosphorylation
Muscle Development
Myoblasts
Skeletal Muscle Fibers
Muscle
2009
59 Citations (Scopus)

A novel in vivo murine model of cartilage regeneration: Age and strain-dependent outcome after joint surface injury

Eltawil, N. M., De Bari, C., Achan, P., Pitzalis, C. & Dell'accio, F., Jun 2009, In : Osteoarthritis and Cartilage. 17, 6, p. 695-704 10 p.

Research output: Contribution to journalArticle

Inbred DBA Mouse
Cartilage
Collagen
Collagen Type II
Regeneration
65 Citations (Scopus)

Distinct mesenchymal progenitor cell subsets in the adult human synovium

Karystinou, A., Dell'Accio, F., Kurth, T. B. A., Wackerhage, H., Khan, I. M., Archer, C. W., Jones, E. A., Mitsiadis, T. A. & De Bari, C., Sep 2009, In : Rheumatology. 48, 9, p. 1057-1064 8 p.

Research output: Contribution to journalArticle

Synovial Membrane
Mesenchymal Stromal Cells
Telomerase
Clone Cells
Population

Mesenchymal stem cells find their niches in skeletal regenerative medicine

de Bari, C., 1 Aug 2009, In : European Cells and Materials. 18, SUPPL. 1, 1 p.

Research output: Contribution to journalArticle

2008
93 Citations (Scopus)

A biomarker-based mathematical model to predict bone-forming potency of human synovial and periosteal mesenchymal stem cells

De Bari, C., Dell'Accio, F., Karystinou, A., Guillot, P. V., Fisk, N. M., Jones, E. A., McGonagle, D., Khan, I. M., Archer, C. W., Mitsiadis, T. A., Donaldson, A. N., Luyten, F. P. & Pitzalis, C., Jan 2008, In : Arthritis & Rheumatism. 58, 1, p. 240-250 11 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Apoptosis in developmental and repair-related human tooth remodeling: a view from the inside

Mitsiadis, T. A., De Bari, C. & About, I., 15 Feb 2008, In : Experimental Cell Research. 314, 4, p. 869-877 9 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

A regulatory relationship between Tbx1 and FGF signaling during tooth morphogenesis and ameloblast lineage determination

Mitsiadis, T. A., Tucker, A. S., De Bari, C., Cobourne, M. T. & Rice, D. P. C., 1 Aug 2008, In : Developmental Biology. 320, 1, p. 39-48 10 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

Comparative osteogenic transcription profiling of various fetal and adult mesenchymal stem cell sources

Guillot, P. V., De Bari, C., Dell'Accio, F., Kurata, H., Polak, J. & Fisk, N. M., Nov 2008, In : Differentiation: Research in Biological Diversity. 76, 9, p. 946-957 12 p.

Research output: Contribution to journalArticle

Adult Stem Cells
Mesenchymal Stromal Cells
Bone Marrow
Fetal Stem Cells
Fetal Blood
114 Citations (Scopus)

Identification of the molecular response of articular cartilage to injury, by microarray screening

Dell'Accio, F., De Bari, C., Eltawil, N. A., Vanhummelen, P. & Pitzalis, C., May 2008, In : Arthritis & Rheumatism. 58, 5, p. 1410-1421 12 p.

Research output: Contribution to journalArticle

111 Citations (Scopus)

Stem cells for tooth engineering

Bluteau, G., Luder, H. U., De Bari, C. & Mitsiadis, T. A., 31 Jul 2008, In : European Cells & Materials. 16, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Cell Engineering
Stem cells
Tooth
Stem Cells
Enamels
12 Citations (Scopus)

The large functional spectrum of the heparin-binding cytokines MK and HB-GAM in continuously growing organs: The rodent incisor as a model

Mitsiadis, T. A., Caton, J., De Bari, C. & Bluteau, G., 1 Aug 2008, In : Developmental Biology. 320, 1, p. 256-266 11 p.

Research output: Contribution to journalArticle

2007
144 Citations (Scopus)

Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis

Lories, R. J. U., Derese, I., De Bari, C. & Luyten, F. P., 1 Feb 2007, In : Arthritis & Rheumatism. 56, 2, p. 489-497 9 p.

Research output: Contribution to journalArticle

Spondylarthritis
Tumor Necrosis Factor-alpha
Joints
Inflammation
Arthritis
109 Citations (Scopus)
5 Downloads (Pure)

Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005

Tyndall, A., Walker, U. A., Cope, A., Dazzi, F., De Bari, C., Fibbe, W., Guiducci, S., Jones, S., Jorgensen, C., Le Blanc, K., Luyten, F., McGonagle, D., Martin, I., Bocelli-Tyndall, C., Pennesi, G., Pistoia, V., Pitzalis, C., Uccelli, A., Wulffraat, N. & Feldmann, M., 1 Jan 2007, In : Arthritis Research & Therapy. 9, 1, p. 301

Research output: Contribution to journalArticle

Open Access
File
Rheumatology
Mesenchymal Stromal Cells
Autoimmune Diseases
B-Lymphocytes
Graft vs Host Disease
10 Citations (Scopus)

Lessons from musculoskeletal stem cell research: The key to successful regenerative medicine development

McGonagle, D., De Bari, C., Arnold, P. & Jones, E., Mar 2007, In : Arthritis & Rheumatism. 56, 3, p. 714-721 8 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Mesenchymal stem cells in rheumatology: A regenerative approach to joint repair

De Bari, C. & Dell'accio, F., 1 Oct 2007, In : Clinical Science. 113, 8, p. 339-348 10 p.

Research output: Contribution to journalArticle

Rheumatology
Mesenchymal Stromal Cells
Joints
Arthritis
Stem Cells
158 Citations (Scopus)

Stem cell niches in mammals

Mitsiadis, T. A., Barrandon, O., Rochat, A., Barrandon, Y. & De Bari, C., 1 Oct 2007, In : Experimental Cell Research. 313, 16, p. 3377-3385 9 p.

Research output: Contribution to journalArticle

Stem Cell Niche
Mammals
Stem Cells
Homeostasis
Asymmetric Cell Division
2006
95 Citations (Scopus)
4 Downloads (Pure)

Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury

Dell'Accio, F., De Bari, C., El Tawil, N. M. F., Barone, F., Mitsiadis, T. A., O'Dowd, J. & Pitzalis, C., 1 Jan 2006, In : Arthritis Research & Therapy. 8, 5, p. R139

Research output: Contribution to journalArticle

Open Access
File
Bone Morphogenetic Proteins
Articular Cartilage
Joints
Wounds and Injuries
Osteoarthritis
86 Citations (Scopus)

Efficient lentiviral transduction and improved engraftment of human bone marrow mesenchymal cells

Van Damme, A., Thorrez, L., Ma, L., Vandenburgh, H., Eyckmans, J., Dell'Accio, F., De Bari, C., Luyten, F., Lillicrap, D., Collen, D., VandenDriessche, T. & Chuah, M. K. L., Apr 2006, In : Stem Cells. 24, 4, p. 896-907 12 p.

Research output: Contribution to journalArticle

Green Fluorescent Proteins
Bone Marrow Cells
Stem Cells
Cytomegalovirus
Mesenchymal Stromal Cells
283 Citations (Scopus)

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis

De Bari, C., Dell'Accio, F., Vanlauwe, J., Eyckmans, J., Khan, I. M., Archer, C. W., Jones, E. A., Mcgonagle, D., Mitsiadis, T. A., Pitzalis, C. & Luyten, F. P., Apr 2006, In : Arthritis & Rheumatism. 54, 4, p. 1209-1221 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Reparative medicine: from tissue engineering to joint surface regeneration

De Bari, C., Pitzalis, C. & Dell'Accio, F., 1 Jan 2006, In : Regenerative Medicine. 1, 1, p. 59-69 11 p.

Research output: Contribution to journalArticle

Tissue Engineering
Tissue engineering
Medicine
Regeneration
Joints
2005
24 Citations (Scopus)

Increased Bcl-2/p53 ratio in human osteoarthritic cartilage: a possible role in regulation of chondrocyte metabolism

Iannone, F., De Bari, C., Scioscia, C., Patella, V. & Lapadula, G., 1 Feb 2005, In : Annals of the Rheumatic Diseases. 64, 2, p. 217-221 5 p.

Research output: Contribution to journalArticle

Cartilage
Chondrocytes
Metabolism
Propidium
Thymidine
2003
34 Citations (Scopus)

Bone marrow mesenchymal cells for haemophilia A gene therapy using retroviral vectors with modified long-terminal repeats

Van Damme, A., Chuah, M. K. L., Dell'accio, F., De Bari, C., Luyten, F., Collen, D. & VandenDriessche, T., 1 Jan 2003, In : Haemophilia. 9, 1, p. 94-103 10 p.

Research output: Contribution to journalArticle

Terminal Repeat Sequences
Hemophilia A
Hematopoietic Stem Cells
Bone Marrow Cells
Genetic Therapy