• 4459 Citations
1987 …2019
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Personal profile

Research Interests:

I am particularly interested in the effects of environmental chemicals on reproductive development in the fetus and subsequent reproductive capacity in adults. A major focus of my group is human fetal development and how it is disturbed by exposure to chemicals in the environment, including cigarette smoke.

Fingerprint Dive into the research topics where Paul Alfred François Fowler is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Mothers Medicine & Life Sciences
Smoking Medicine & Life Sciences
Fetus Medicine & Life Sciences
Pregnancy Medicine & Life Sciences
Sheep Medicine & Life Sciences
Smoke Medicine & Life Sciences
Sewage Medicine & Life Sciences
Fetal Development Medicine & Life Sciences

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Research Output 1987 2019

7 Citations (Scopus)
10 Downloads (Pure)

Alternative (backdoor) androgen production and masculinization in the human fetus

O'Shaughnessy, P. J., Antignac, J-P., Le Bizec, B., Morvan, M-L., Svechnikov, K., Söder, O., Savchuk, I., Monteiro, A., Soffientini, U., Johnston, Z. C., Bellingham, M., Hough, D., Walker, N., Filis, P. & Fowler, P., 14 Feb 2019, In : PLoS Biology. 17, 2, e3000002.

Research output: Contribution to journalArticle

Open Access
File
androsterone
Androsterone
masculinization
androgens
Androgens
1 Citation (Scopus)
6 Downloads (Pure)

Long-term exposure to chemicals in sewage sludge fertilizer alters liver lipid content in females and cancer marker expression in males

Filis, P., Walker, N., Robertson, L., Eaton-Turner, E., Ramona, L., Bellingham, M., Amezaga, M. R., Zhang, Z., Mandon-Pepin, B., Evans, N. P., Sharpe, R. M., Cotinot, C., Rees, W. D., O'Shaughnessy, P. & Fowler, P. A., Mar 2019, In : Environment International. 124, p. 98-108 10 p.

Research output: Contribution to journalArticle

Open Access
File
cancer
lipid
fertilizer
protein
culling
1 Citation (Scopus)
4 Downloads (Pure)

Nutrient transporter expression in both the placenta and fetal liver are affected by maternal smoking

Walker, N., Filis, P., O'Shaughnessy, P. J., Bellingham, M. & Fowler, P. A., Mar 2019, In : Placenta. 78, p. 10-17 8 p.

Research output: Contribution to journalArticle

Open Access
File
Placenta
Smoking
Mothers
Food
Liver
2 Citations (Scopus)
4 Downloads (Pure)

Maternal smoking and high BMI disrupt thyroid gland development

Filis, P., Hombach-Klonisch, S., Ayotte, P., Nagrath, N., Soffientini, U., Klonisch, T., O'Shaughnessy, P. J. & Fowler, P. A., 23 Oct 2018, In : BMC medicine . 16, 194.

Research output: Contribution to journalArticle

Open Access
File
Thyroid Gland
Body Mass Index
Smoking
Mothers
Thyrotropin
3 Citations (Scopus)
5 Downloads (Pure)

Quantification of ethyl glucuronide, ethyl sulfate, nicotine, and its metabolites in human fetal liver and placenta

Swortwood, M. J., Bartock, S. H., Scheidweiler, K. B., Shaw, S., Filis, P., Douglas, A., O'Shaughnessy, P. J., Soffientini, U., Lucendo-Villarin, B., Iredale, J. P., Hay, D. C., Fowler, P. A. & Huestis, M. A., Jan 2018, In : Forensic Toxicology. 36, 1, p. 102-112 11 p.

Research output: Contribution to journalArticle

Open Access
File
Metabolites
Nicotine
Liver
Placenta
Tobacco