If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where Shinichiro Hiraga is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
DNA Replication Medicine & Life Sciences
Protein Phosphatase 1 Medicine & Life Sciences
Replication Origin Medicine & Life Sciences
Saccharomycetales Medicine & Life Sciences
DNA Chemical Compounds
Telomere Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Proteins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2006 2019

Human RIF1-Protein Phosphatase 1 prevents degradation and breakage of nascent DNA on replication stalling

Garzón, J., Ursich, S., Lopes, M., Hiraga, S. & Donaldson, A. D., 28 May 2019, In : Cell Reports. 27, 9, p. 2558-2566 13 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Phosphatase 1
DNA Replication
Degradation
DNA
Genomic Instability
6 Citations (Scopus)
5 Downloads (Pure)

Budding yeast Rif1 binds to replication origins and protects DNA at blocked replication forks

Hiraga, S., Monerawela, C., Katou, Y., Shaw, S., Clark, K. R. M., Shirahige, K. & Donaldson, A. D., 1 Sep 2018, In : EMBO reports. 19, 9, p. 1-14 14 p., e46222.

Research output: Contribution to journalArticle

Open Access
File
Saccharomycetales
Replication Origin
Hydroxyurea
Yeast
DNA Replication
5 Citations (Scopus)
5 Downloads (Pure)

Rif1 acts through Protein Phosphatase 1 but independent of replication timing to suppress telomere extension in budding yeast

Kedziora, S., Gali, V. K., Wilson, R. H. C., Clark, K. R. M., Nieduszynski, C. A., Hiraga, S. & Donaldson, A. D., 4 May 2018, In : Nucleic Acids Research. 46, 8, p. 3993-4003 11 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Phosphatase 1
Saccharomycetales
Telomere
Replication Origin
Telomere Homeostasis
35 Citations (Scopus)
5 Downloads (Pure)

Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation

Hiraga, S., Ly, T., Garzon, J., Hořejší, Z., Ohkubo, Y., Endo, A., Obuse, C., Boulton, S. J., Lamond, A. I. & Donaldson, A. D., 1 Mar 2017, In : EMBO reports. 18, 3, p. 403-419 17 p., e201641983.

Research output: Contribution to journalArticle

Open Access
File
Protein Phosphatase 1
Replication Origin
Licensure
DNA Replication
Chemical activation
Staphylococcal Protein A
Protein Phosphatase 1
DNA Replication
Proteins
G1 Phase

Activities 2003 2018

  • 9 Conference
  • 8 Invited talk
  • 1 Workshop, seminar, or course
  • 1 Oral presentation

Function of human RIF1 protein during and after replication stress

Shinichiro Hiraga (Author), Lotte Watts (Author), Chandre Adam Monerawela (Author), Javier Garzón (Author), Anne Dunlop Donaldson (Author)
19 Nov 2018

Activity: Talk, presentation, public lecture, public engagement, outreach and knowledge exchangeInvited talk

RIF1 protects cells from replication stress:When and Which splice variant?

Shinichiro Hiraga (Author), Lotte Watts (Author), Anne Dunlop Donaldson (Author)
13 Nov 2018

Activity: Talk, presentation, public lecture, public engagement, outreach and knowledge exchangeOral presentation

Function of human RIF1 protein during and after replication stress

Shinichiro Hiraga (Speaker)
22 Nov 2018

Activity: Talk, presentation, public lecture, public engagement, outreach and knowledge exchangeInvited talk

3R&3C Symposium 2018

Shinichiro Hiraga (Speaker)
12 Nov 201816 Nov 2018

Activity: Participating in or organising an eventConference

Rif1-PP1 function in other than controlling DNA replication

Shinichiro Hiraga (Speaker)
20 Mar 2018

Activity: Talk, presentation, public lecture, public engagement, outreach and knowledge exchangeInvited talk