Research output per year
Research output per year
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Dive into the research topics where Shinichiro Hiraga is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region
Balasubramanian, S., Andreani, M., Andrade, J. G., Saha, T., Sundaravinayagam, D., Garzón, J., Zhang, W., Popp, O., Hiraga, S-I., Rahjouei, A., Rosen, D. B., Mertins, P., Chait, B. T., Donaldson, A. D. & Di Virgilio, M., 13 Apr 2022, In: eLife. 11, 30 p., e75047.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)3 Downloads (Pure) -
SAF-A promotes origin licensing and replication fork progression to ensure robust DNA replication
Connolly, C., Takahashi, S., Miura, H., Hiratani, I., Gilbert, N., Donaldson, A. & Hiraga, S., 24 Jan 2022, In: Journal of Cell Science. 135, 2, 15 p., jcs.258991.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)2 Downloads (Pure) -
Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action
Isobe, S-Y., Hiraga, S., Nagao, K., Sasanuma, H., Donaldson, A. D. & Obuse, C., 13 Jul 2021, In: Cell Reports. 36, 2, 18 p., 109383.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)1 Downloads (Pure) -
Replication timing maintains the global epigenetic state in human cells
Klein, K. N., Zhao, P. A., Lyu, X., Sasaki, T., Bartlett, D. A., Singh, A. M., Tasan, I., Zhang, M., Watts, L. P., Hiraga, S., Natsume, T., Zhou, X., Baslan, T., Leung, D., Kanemaki, M. T., Donaldson, A. D., Zhao, H., Dalton, S., Corces, V. G. & Gilbert, D. M., 23 Apr 2021, In: Science. 372, 6540, p. 371-378 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile47 Citations (Scopus)1 Downloads (Pure) -
The RIF1-Long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress
Watts, L. P., Natsume, T., Saito, Y., Garzon, J., Dong, Q., Boteva, L., Gilbert, N., Kanemaki, M. T., Hiraga, S-I. & Donaldson, A. D., 3 Nov 2020, In: eLife. 9, 26 p., e58020.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)1 Downloads (Pure)
Datasets
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Rif1 acts through Protein Phosphatase 1 and independent of replication timing to suppresses telomere extension in budding yeast
Kedziora, S. (Creator), Gali, V. (Creator), Wilson, R. (Creator), Clark, K. (Creator), Nieduszynski, C. A. (Creator), Hiraga, S. (Creator) & Donaldson, A. (Creator), GEO, 14 Feb 2018
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE109241
Dataset
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Single-cell replication timing analysis of hTERT-RPE1 cells depleted for SAF-A protein
Hiraga, S. (Creator), EMBL-EBI, 15 Dec 2021
https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-10234/
Dataset
Activities
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SAF-A is required for normal DNA replication via creating open chromatin
Shinichiro Hiraga (Speaker)
Oct 2021Activity: Disseminating Research › Presentation
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Chromatin-organising protein SAF-A is required for robust DNA replication
Shinichiro Hiraga (Speaker)
26 Mar 2021Activity: Disseminating Research › Workshop, Seminar or Course
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Requirement for SAF-A/HNRNPU in establishing an open chromatin structure needed for multiple steps in DNA replication
Shinichiro Hiraga (Speaker)
9 Sep 2021Activity: Disseminating Research › Presentation
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DNA (Journal)
Shinichiro Hiraga (Peer Review)
2021 → …Activity: Publication peer-review and editorial work › Editor of research journal / publication series
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RIF1 protein protects chromosome integrity from DNA replication stress at multiple points
Shinichiro Hiraga (Speaker)
17 Jul 2019Activity: Disseminating Research › Invited talk