Stephen Makin

2024

Clinical Associations and Prognostic Value of MRI-Visible Perivascular Spaces in Patients With Ischemic Stroke or TIA: A Pooled Analysis

Best, J. G., Ambler, G., Wilson, D., Du, H., Lee, K. J., Lim, J. S., Teo, K. C., Mak, H., Kim, Y. D., Song, T. J., Selcuk Demirelli, D., Nishihara, M., Yoshikawa, M., Kubacka, M., Zietz, A., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y. H., Panos, L., Goeldlin, M. B., & 30 othersSlater, L. A., Karayiannis, C. C., Phan, T. G., Bellut, M., Abrigo, J., Cheng, C., Leung, T. W., Chu, W., Chappell, F., Makin, S. D. J., Van Dam-Nolen, D. H. K., Kooi, M. E., Köhler, S., Staals, J., Kuchcinski, G., Bordet, R., Dubost, F., Wardlaw, J. M., Soo, Y. O. Y., Fluri, F., Srikanth, V. K., Jung, S., Peters, N., Hara, H., Yakushiji, Y., Necioglu Orken, D., Heo, J. H., Lau, G. K. K., Bae, H. J. & Werring, D. J., 9 Jan 2024, In: Neurology. 102, 1, 14 p., e207795.

Research output: Contribution to journal › Article › peer-review

Open Access

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2023

Validated frailty measures using electronic primary care records: a review of diagnostic test accuracy

Brack, C., Kynn, M., Murchie, P. & Makin, S., 17 Nov 2023, In: Age and Ageing. 52, 11, 9 p., afad173.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

Sex Differences in Poststroke Cognitive Impairment: A Multicenter Study in 2343 Patients With Acute Ischemic Stroke

Exalto, L. G., Weaver, N. A., Kuijf, H. J., Aben, H. P., Bae, H. J., Best, J. G., Bordet, R., Chen, C. P. L. H., Van Der Giessen, R. S., Godefroy, O., Gyanwali, B., Hamilton, O. K. L., Hilal, S., Huenges Wajer, I. M. C., Kim, J., Kappelle, L. J., Kim, B. J., Köhler, S., De Kort, P. L. M., Koudstaal, P. J., & 16 othersLim, J. S., Makin, S. D. J., Mok, V. C. T., Van Oostenbrugge, R. J., Roussel, M., Staals, J., Valdés-Hernández, M. D. C., Venketasubramanian, N., Verhey, F. R. J., Wardlaw, J. M., Werring, D. J., Xu, X., Van Zandvoort, M. J. E., Biesbroek, J. M., Chappell, F. M. & Biessels, G. J., 1 Sept 2023, In: Stroke. 54, 9, p. 2296-2303 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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4 Citations (Scopus)

Impact of Cerebral Microbleeds in Stroke Patients with Atrial Fibrillation

Soo, Y., Zietz, A., Yiu, B., Mok, V. C. T., Polymeris, A. A., Seiffge, D., Ambler, G., Wilson, D., Leung, T. W. H., Tsang, S. F., Chu, W., Abrigo, J., Cheng, C., Lee, K-J., Lim, J-S., Shiozawa, M., Koga, M., Chabriat, H., Hennerici, M., Wong, Y. K., & 89 othersMak, H., Collet, R., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., Lam, B. Y. K., Wong, A., Kim, Y. D., Song, T-J., Lemmens, R., Eppinger, S., Gattringer, T., Uysal, E., Demirelli, D. S., Bornstein, N. M., Assayag, E. B., Hallevi, H., Molad, J., Nishihara, M., Tanaka, J., Coutts, S. B., Kappelle, L. J., Al-Shahi Salman, R., Jager, R., Lip, G. Y. H., Goeldlin, M. B., Panos, L. D., Mas, J-L., Legrand, L., Karayiannis, C., Phan, T., Bellut, M., Chappell, F., Makin, S., Hayden, D., Williams, D., van Dam-Nolen, D. H. K., Nederkoorn, P. J., Barbato, C., Browning, S., Wiegertjes, K., Tuladhar, A. M., Mendyk, A-M., Köhler, S., van Oostenburgge, R., Zhou, Y., Xu, C., Hilal, S., Gyanwali, B., Chen, C., Lou, M., Staals, J., Bordet, R., Kandiah, N., de Leeuw, F-E., Simister, R., Hendrikse, J., Wardlaw, J., Kelly, P., Fluri, F., Srikanth, V., Calvet, D., Jung, S., Kwa Vincent, I. H., Smith, E. E., Hara, H., Yakushiji, Y., Orken, D. N., Fazekas, F., Thijs, V., Heo, J-H., Veltkamp, R., Ay, H., Imaizumi, T., Lau, K. K., Jouvent, E., Toyoda, K., Yoshimura, S., Bae, H-J., Martí-Fàbregas, J., Prats-Sánchez, L., Lyrer, P., Best, J., Werring, D., Engelter, S. T., Peters, N. & Network, T. M. I. C., Jul 2023, In: Annals of Neurology. 94, 1, p. 61-74 14 p.

Research output: Contribution to journal › Article › peer-review

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7 Citations (Scopus)

Development of a UK core dataset for geriatric medicine research: a position statement and results from a Delphi consensus process

Welch, C., Wilson, D., Sayer, A. A., Witham, M. D., Jackson, T. A. & UK Geriatric Medicine Core Dataset Extended Working Group, 23 Mar 2023, In: BMC Geriatrics. 23, 11 p., 168.

Research output: Contribution to journal › Article › peer-review

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Predicting incident dementia in cerebral small vessel disease: comparison of machine learning and traditional statistical models

Li, R., Harshfield, E. L., Bell, S., Burkhart, M., Tuladhar, A. M., Hilal, S., Tozer, D. J., Chappell, F. M., Makin, S. D. J., Lo, J. W., Wardlaw, J. M., de Leeuw, F. E., Chen, C., Kourtzi, Z. & Markus, H. S., 2023, In: Cerebral Circulation - Cognition and Behavior. 5, 8 p., 100179.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

2022

DIAGNOSTIC TEST ACCURACY OF FRAILTY SCREENING TOOLS USING DATA IN ELECTRONIC PRIMARY CARE RECORDS

Makin, S., Brack, C., Kynn, M. & Murchie, P., Jun 2022, In: Age and Ageing. 51, SUPPL 2, 1 p., 1013.

Research output: Contribution to journal › Abstract › peer-review

Network impact score is an independent predictor of post-stroke cognitive impairment: a multicenter cohort study in 2341 patients with acute ischemic stroke.

Weaver, N. A., Aben, H. P., Kuijf, H. J., Abrigo, J., Bae, H-J., Barbay, M., Best, J. G., Bordet, R., Chappell, F. M., Chen, C. P. L. H., Dondaine, T., van der Giessen, R. S., Godefroy, O., Gyanwali, B., Hamilton, O. K. L., Hilal, S., Huenges Wajer, I. M. C., Kang, Y., Kappelle, L. J., Kim, B. J., & 28 othersKöhler, S., de Kor, P. L. M., Koudstaal, P. J., Kuchcinski, G., Lam, B. Y. K., Lee, B-C., Lee, K-J., Lim, J-S., Lopes, R., Makin, S., Mendyk, A-M., Mok, V. C. T., Oh, M. S., Van Oostenbrugge, R. J., Roussel, M., Shi, L., Staals, J., Valdés Hernández, M. D. C., Venketasubramanian, N., Verhey, F. R. J., Wardlaw, J. M., Werring, D. J., Xin, X., Yu, K-H., van Zandvoort, M. J. E., Zhao, L., Biessels, G. J. & Biesbroek, J. M., 30 Apr 2022, In: NeuroImage: Clinical. 34, 7 p., 103018.

Research output: Contribution to journal › Article › peer-review

Open Access

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6 Citations (Scopus)

2 Downloads (Pure)

Impact of Small Vessel Disease Progression on Long-term Cognitive and Functional Changes after Stroke

Clancy, U., Makin, S. D. J., McHutchison, C. A., Cvoro, V., Chappell, F. M., Hernández, M. D. C. V., Sakka, E., Doubal, F. & Wardlaw, J. M., 5 Apr 2022, In: Neurology. 98, 14, p. E1459-E1469 12 p.

Research output: Contribution to journal › Article › peer-review

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8 Citations (Scopus)

4 Downloads (Pure)

2021

Tracer kinetic assessment of blood–brain barrier leakage and blood volume in cerebral small vessel disease: Associations with disease burden and vascular risk factors

Stringer, M. S., Heye, A. K., Armitage, P. A., Chappell, F., Valdés Hernández, M. D. C., Makin, S. D. J., Sakka, E., Thrippleton, M. J. & Wardlaw, J. M., Nov 2021, In: NeuroImage: Clinical. 32, 9 p., 102883.

Research output: Contribution to journal › Article › peer-review

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8 Citations (Scopus)

9 Downloads (Pure)

Potential recruitment into a clinical trial of vascular secondary prevention medications in cerebral small vessel disease, based on concomitant medication use

Morrison, E., Lyall, D. M., Pell, J. P., Mackay, D. F., Doubal, F. N., Wardlaw, J. M., Quinn, T. J. & Makin, S., 1 Jun 2021, In: Cerebral Circulation - Cognition and Behavior. 2, 5 p., 100015.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

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A four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakage

Bernal, J., Valdés-Hernández, M. D. C., Escudero, J., Heye, A. K., Sakka, E., Armitage, P. A., Makin, S., Touyz, R. M., Wardlaw, J. M. & Thrippleton, M. J., 15 Apr 2021, In: Neuroimage. 230, 12 p., 117786.

Research output: Contribution to journal › Article › peer-review

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14 Citations (Scopus)

7 Downloads (Pure)

Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies

Best, J. G., Ambler, G., Wilson, D., Lee, K-J., Lim, J-S., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sanchez, L., Martinez-Domeno, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., & 86 othersLam, B. Y. K., Wong, A., Kim, Y. D., Song, T-J., Lemmens, R., Eppinger, S., Gattringer, T., Uysal, E., Tanriverdi, Z., Bornstein, N. M., Ben Assayag, E., Hallevi, H., Molad, J., Nishihara, M., Tanaka, J., Coutts, S. B., Polymeris, A., Wagner, B., Seiffge, D. J., Lyrer, P., Algra, A., Kappelle, L. J., Salman, R. A-S., Jager, H. R., Lip, G. Y. H., Fischer, U., El-Koussy, M., Mas, J-L., Legrand, L., Karayiannis, C., Phan, T., Gunkel, S., Christ, N., Abrigo, J., Leung, T., Chu, W., Chappell, F. M., Makin, S., Hayden, D., Williams, D. J., Mess, W. H., Nederkoorn, P. J., Barbato, C., Browning, S., Wiegertjes, K., Tuladhar, A. M., Maaijwee, N., Guevarra, A. C., Yatawara, C., Mendyk, A-M., Delmaire, C., Köhler, S., van Oostenbrugge, R., Zhou, Y., Xu, C., Hilal, S., Gyanwali, B., Chen, C., Lou, M., Staals, J., Bordet, R., Kandiah, N., de Leeuw, F-E., Simister, R., Hendrikse, J., Calvet, D., Jung, S., Kwa, V. I. H., Engelter, S. T., Peters, N., Fazekas, F., Thijs, V., Heo, J. H., Mok, V., Veltkamp, R., Ay, H., Imaizumi, T., Gomez-Anson, B., Lau, K. K., Jouvent, E., Rothwell, P. M., Toyoda, K., Bae, H-J., Marti-Fabregas, J., Werring, D. J. & Microbleeds Int Collaborative, 1 Apr 2021, In: The Lancet neurology. 20, 4, p. 294-303 10 p.

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Lacunar Stroke Lesion Extent and Location and White Matter Hyperintensities Evolution 1 Year Post-lacunar Stroke

Valdés Hernández, M. D. C., Grimsley-Moore, T., Sakka, E., Thrippleton, M. J., Chappell, F. M., Armitage, P. A., Makin, S. & Wardlaw, J. M., 5 Mar 2021, In: Frontiers in Neurology. 12, 13 p., 640498.

Research output: Contribution to journal › Article › peer-review

Open Access

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5 Citations (Scopus)

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Post-stroke cognition at 1 and 3 years is influenced by the location of white matter hyperintensities in patients with lacunar stroke

Valdés Hernández, M. D. C., Grimsley-Moore, T., Chappell, F. M., Thrippleton, M. J., Armitage, P. A., Sakka, E., Makin, S. & Wardlaw, J. M., 1 Mar 2021, In: Frontiers in Neurology. 12, 13 p., 634460.

Research output: Contribution to journal › Article › peer-review

Open Access

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6 Citations (Scopus)

6 Downloads (Pure)

Probabilistic Deep Learning with Adversarial Training and Volume Interval Estimation - Better Ways to Perform and Evaluate Predictive Models for White Matter Hyperintensities Evolution

Rachmadi, M. F., Valdés-Hernández, M. D. C., Maulana, R., Wardlaw, J., Makin, S. & Skibbe, H., 2021, Predictive Intelligence in Medicine, PRIME 2021. Rekik, I., Adeli, E., Park, S. H. & Schnabel, J. (eds.). Cham: Springer , Vol. 12928. p. 168-180 13 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 12928 LNCS).

Research output: Chapter in Book/Report/Conference proceeding › Published conference contribution

2020

The use of transcranial ultrasound and clinical assessment to diagnose ischaemic stroke due to large vessel occlusion in remote and rural areas.

Antipova, D., Eadie, L., Makin, S., Shannon, H., Wilson, P. & MacAden, A., Oct 2020, In: PloS ONE. 15, 10, 18 p., e0239653.

Research output: Contribution to journal › Article › peer-review

Open Access

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19 Citations (Scopus)

3 Downloads (Pure)

Growing research in geriatric medicine: a trainee perspective

Welch, C. & Geriatric Medicine Research Collaborative, Sept 2020, In: Age and Ageing. 49, 5, p. 733-737 5 p.

Research output: Contribution to journal › Article

4 Citations (Scopus)

Preparing for a challenging winter 2020/21

Yiangou, A., Makin, S., Cope, C. & Laycock, E., 14 Jul 2020, The Academy of Medical Sciences. 79 p.

Research output: Book/Report › Other Report

Open Access

Automatic spatial estimation of white matter hyperintensities evolution in brain MRI using disease evolution predictor deep neural networks

Rachmadi, M. F., Valdés-Hernández, M. D. C., Makin, S., Wardlaw, J. & Komura, T., Jul 2020, In: Medical image analysis. 63, p. 101712 19 p., 101712.

Research output: Contribution to journal › Article › peer-review

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18 Citations (Scopus)

13 Downloads (Pure)

Predictors of Lesion Cavitation After Recent Small Subcortical Stroke.

Gattringer, T., Valdes, H. M., Heye, A., Armitage, PA., Makin, S., Chappell, F., Pinter, D., Doubal, F., Enzinger, C., Fazekas, F. & Wardlaw, JM., Jun 2020, In: Translational Stroke Research. 11, p. 402-411 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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11 Citations (Scopus)

4 Downloads (Pure)

Analysis of dynamic texture and spatial spectral descriptors of dynamic contrast-enhanced brain magnetic resonance images for studying small vessel disease

Bernal, J., Valdés-Hernández, MDC., Escudero, J., Viksne, L., Heye, AK., Armitage, PA., Makin, S., Touyz, RM. & Wardlaw, JM., Feb 2020, In: Magnetic Resonance Imaging. 66, p. 240-247 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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6 Citations (Scopus)

4 Downloads (Pure)

2019

The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: Design and multicenter pilot study

Weaver, N. A., Zhao, L., Biesbroek, J. M., Kuijf, H. J., Aben, H. P., Bae, H. J., Caballero, M. A. A., Chappell, F. M., Chen, C., Dichgans, M., Duering, M., Georgakis, M. K., van der Giessen, R. S., Gyanwali, B., Hamilton, O. K. L., Hilal, S., Vom Hofe, E. M., de Kort, P. L. M., Koudstaal, P. J., Lam, B. Y. K., & 12 othersLim, J. S., Makin, S. D. J., Mok, V. C. T., Shi, L., Valdes Hernandez, M. C., Venketasubramanian, N., Wardlaw, J. M., Wollenweber, F. A., Wong, A., Xin, X., Meta, V. C. I. M. C. & Biessels, G. J., Dec 2019, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 11, p. 310-326 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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30 Citations (Scopus)

5 Downloads (Pure)

Accuracy of the short-form Montreal Cognitive Assessment: Systematic review and validation

McDicken, J. A., Elliott, E., Blayney, G., Makin, S., Ali, M., Larner, A. J., Quinn, T. J. & Collaborators, VISTA-C., Oct 2019, In: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 34, 10, p. 1515-1525 11 p.

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Intensive Blood Pressure Lowering in Patients With Renal Impairment and Lacunar Stroke

Makin, S. & Whiteley, W. N., 20 Aug 2019, In: Journal of the American Heart Association. 8, 16, e013637.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

6 Downloads (Pure)

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies

Wilson, D., Ambler, G., Lee, K-J., Lim, J-S., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sánchez, L., Martínez-Domeño, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., Lam, B. Y. K., & 291 othersWong, A., Kim, Y. D., Song, T-J., Schrooten, M., Lemmens, R., Eppinger, S., Gattringer, T., Uysal, E., Tanriverdi, Z., Bornstein, N. M., Assayag, E. B., Hallevi, H., Tanaka, J., Hara, H., Coutts, S. B., Hert, L., Polymeris, A., Seiffge, D. J., Lyrer, P., Algra, A., Kappelle, J., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y. H., Mattle, H. P., Panos, L. D., Mas, J-L., Legrand, L., Karayiannis, C., Phan, T., Gunkel, S., Christ, N., Abrigo, J., Leung, T., Chu, W., Chappell, F., Makin, S., Hayden, D., Williams, D. J., Kooi, M. E., van Dam-Nolen, D. H. K., Barbato, C., Browning, S., Wiegertjes, K., Tuladhar, A. M., Maaijwee, N., Guevarra, C., Yatawara, C., Mendyk, A-M., Delmaire, C., Köhler, S., van Oostenbrugge, R., Zhou, Y., Xu, C., Hilal, S., Gyanwali, B., Chen, C., Lou, M., Staals, J., Bordet, R., Kandiah, N., de Leeuw, F-E., Simister, R., van der Lugt, A., Kelly, P. J., Wardlaw, J. M., Soo, Y., Fluri, F., Srikanth, V., Calvet, D., Jung, S., Kwa, V. I. H., Engelter, S. T., Peters, N., Smith, E. E., Yakushiji, Y., Orken, D. N., Fazekas, F., Thijs, V., Heo, J. H., Mok, V., Veltkamp, R., Ay, H., Imaizumi, T., Gomez-Anson, B., Lau, K. K., Jouvent, E., Rothwell, P. M., Toyoda, K., Bae, H-J., Marti-Fabregas, J., Werring, D. J., Harkness, K., Shaw, L., Sword, J., Mohd Nor, A., Sharma, P., Kelly, D., Harrington, F., Randall, M., Smith, M., Mahawish, K., Elmarim, A., Esisi, B., Cullen, C., Nallasivam, A., Price, C., Barry, A., Roffe, C., Coyle, J., Hassan, A., Birns, J., Cohen, D., Sekaran, L., Parry-Jones, A., Parry, A., Hargroves, D., Proschel, H., Datta, P., Darawil, K., Manoj, A., Burn, M., Patterson, C., Giallombardo, E., Smyth, N., Mansoor, S., Anwar, I., Marsh, R., Ispoglou, S., Chadha, D., Prabhakaran, M., Meenakishundaram, S., O'Connell, J., Scott, J., Krishnamurthy, V., Aghoram, P., McCormick, M., Sprigg, N., O'Mahony, P., Cooper, M., Choy, L., Wilkinson, P., Leach, S., Caine, S., Burger, I., Gunathilagan, G., Guyler, P., Emsley, H., Davis, M., Manawadu, D., Pasco, K., Mamun, M., Luder, R., Sajid, M., Okwera, J., Warburton, E., Saastamoinen, K., England, T., Putterill, J., Flossman, E., Power, M., Dani, K., Mangion, D., Suman, A., Corrigan, J., Lawrence, E., Vahidassr, D., Shakeshaft, C., Brown, M., Charidimou, A., Cohen, H., Banerjee, G., Houlden, H., White, M., Yousry, T., Flossmann, E., Muir, K., El-Koussy, M., Gratz, P., Molad, J., Korczyn, A., Kliper, E., Maeder, P., Gass, A., Pachai, C., Bracoub, L., Douste-Blazy, M-Y., Fratacci, M. D., Vicaut, E., Sato, S., Miwa, K., Fujita, K., Ide, T., Ma, H., Ly, J., Singhal, S., Chandra, R., Slater, L-A., Soufan, C., Moran, C., Traenka, C., Thilemann, S., Fladt, J., Gensicke, H., Bonati, L., Kim, B. J., Han, M-K., Kang, J., Ko, E., Yang, M. H., Jang, M. S., Murphy, S., Carty, F., Akijian, L., Thornton, J., Schembri, M., Douven, E., Delgado, M., Escudero, R., Marín, R., Camps-Renom, P., Guisado-Alonso, D., Nuñez, F., Medrano-Martorell, S., Merino, E., Iida, K., Ikeda, S., Nishihara, M., Irie, H., Demirelli, D. S., Medanta, J. M., Zerna, C., Hernández, M. V., Armitage, P., Heye, A., Muñoz-Maniega, S., Sakka, E., Thrippleton, M., Dennis, M., Beigneux, Y., Silva, M., Venketasubramanian, N., Ho, S. L., Cheung, R. T. F., Chan, K. H., Teo, K. C., Hui, E., Kwan, J. S. K., Chang, R., Tse, M. Y., Hoi, C. P., Chan, C. Y., Chan, O. L., Cheung, R. H. K., Wong, E. K. M., Leung, K. T., Tsang, S. F., Ip, H. L., Ma, S. H., Ma, K., Fong, W. C., Li, S. H., Li, R., Ng, P. W., Wong, K. K., Liu, W., Wong, L., Ramos, L., De Schryver, E., Jöbsis, J., van der Sande, J., Brouwers, P., Roos, Y., Stam, J., Bakker, S., Verbiest, H., Schoonewille, W., Linn, C., Hertzberger, L., van Gemert, M., Berntsen, P., Hendrikse, J., Nederkoorn, P., Mess, W., Koudstaal, P., Leff, A., Ward, N., Nachev, P., Perry, R., Ozkan, H. & Mitchell, J., 1 Jul 2019, In: The Lancet neurology. 18, 7, p. 653-665 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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144 Citations (Scopus)

3 Downloads (Pure)

Predicting the Evolution of White Matter Hyperintensities in Brain MRI using Generative Adversarial Networks and Irregularity Map

Rachmadi, MF., MdC, V-H., Makin, S., Wardlaw, JM. & Komura, T., 12 Jun 2019, 9 p.

Research output: Other contribution

10 Citations (Scopus)

Identification of the presence of ischaemic stroke lesions by means of texture analysis on brain magnetic resonance images

Ortiz-Ramon, R., Valdes Hernandez, M. D. C., Gonzalez-Castro, V., Makin, S., Armitage, P. A., Aribisala, B. S., Bastin, M. E., Deary, I. J., Wardlaw, J. M. & Moratal, D., Jun 2019, In: Comput Med Imaging Graph. 74, p. 12-24 13 p.

Research output: Contribution to journal › Article › peer-review

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39 Citations (Scopus)

12 Downloads (Pure)

Stability of Estimated Premorbid Cognitive Ability over Time after Minor Stroke and Its Relationship with Post-Stroke Cognitive Ability

McHutchison, C. A., Chappell, F. M., Makin, S., Shuler, K., Wardlaw, J. M. & Cvoro, V., 22 May 2019, In: Brain Sciences. 9, 5, 117.

Research output: Contribution to journal › Article › peer-review

Open Access

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8 Citations (Scopus)

6 Downloads (Pure)

Growing research in geriatric medicine

Witham, M. D., Roberts, H. C., Gladman, J., Stott, D. J., Sayer, A. A., Aspray, T. J., Brock, P., Clegg, A., Cox, N., Ewan, V., Frith, J., Burton, J. K., Jackson, T., Lewis, E. G., Lim, S. E., Makin, S., Lochlainn, M. N., Richardson, S., Shenkin, S. D., Steves, C. J., & 5 othersTodd, O., Tullo, E., Walker, R., Yarnall, A. & Extended Working Group from the NIHR Newcastle Biomedical Research Centre Meeting, May 2019, In: Age and Ageing. 48, 3, p. 316-319 4 p.

Research output: Contribution to journal › Article

8 Citations (Scopus)

Association between Striatal Brain Iron Deposition, Microbleeds and Cognition 1 Year After a Minor Ischaemic Stroke

Valdes Hernandez, M. D. C. V., Case, T., Chappell, F. M., Glatz, A., Makin, S., Doubal, F. & Wardlaw, J. M., 14 Mar 2019, In: International Journal of Molecular Sciences. 20, 6, 1293.

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16 Citations (Scopus)

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Comprehensive Geriatric Assessment in hospital and hospital-at-home settings: a mixed-methods study

Gardner, M., Shepperd, S., Godfrey, M., Mäkelä, P., Tsiachristas, A., Singh-Mehta, A., Ellis, G., Khanna, P., Langhorne, P., Makin, S. & Stott, D. J., 1 Mar 2019, In: Health Services and Delivery Research. 7, 10, p. 1-236 236 p.

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Convolutional Neural Networks for Direct Inference of Pharmacokinetic Parameters: Application to Stroke Dynamic Contrast-Enhanced MRI

Ulas, C., Das, D., Thrippleton, M. J., Valdes Hernandez, M. D. C., Armitage, P. A., Makin, S. D., Wardlaw, J. M. & Menze, B. H., 8 Jan 2019, In: Frontiers in Neurology. 9, 1147.

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10 Citations (Scopus)

4 Downloads (Pure)

Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke

McHutchison, C. A., Cvoro, V., Makin, S., Chappell, F. M., Shuler, K. & Wardlaw, J. M., 2019, In: Journal of Neurology, Neurosurgery & Psychiatry. 90, 4, p. 436-443 8 p.

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34 Citations (Scopus)

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2018

The brain health index: Towards a combined measure of neurovascular and neurodegenerative structural brain injury

Dickie, D. A., Valdes Hernandez, M. D. C., Makin, S. D., Staals, J., Wiseman, S. J., Bastin, M. E. & Wardlaw, J. M., 1 Oct 2018, In: International Journal of Stroke. 13, 8, p. 849-856 8 p.

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Open Access

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17 Citations (Scopus)

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Managing blood pressure in older adults: Age alone is no barrier to treatment

Makin, S. & Stott, D. J., 6 Jul 2018, In: BMJ (Online). 362, k2912.

Research output: Contribution to journal › Editorial › peer-review

5 Citations (Scopus)

The impact of early-life intelligence quotient on post stroke cognitive impairment

Makin, S. D. J., Doubal, F. N., Shuler, K., Chappell, F. M., Staals, J., Dennis, M. S. & Wardlaw, J. M., 1 Jun 2018, In: European Stroke Journal . 3, 2, p. 145-156 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Citations (Scopus)

Long-term morphological changes of symptomatic lacunar infarcts and surrounding white matter on structural magnetic resonance imaging

Loos, C. M. J., Makin, S. D. J., Staals, J., Dennis, M. S., Van Oostenbrugge, R. J. & Wardlaw, J. M., May 2018, In: Stroke. 49, 5, p. 1183-1188 6 p.

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32 Citations (Scopus)

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The effect of different combinations of vascular, dependency and cognitive endpoints on the sample size required to detect a treatment effect in trials of treatments to improve outcome after lacunar and non-lacunar ischaemic stroke

Makin, S. DJ., Doubal, F. N., Quinn, T. J., Bath, P. MW., Dennis, M. S. & Wardlaw, J. M., 2018, In: European Stroke Journal . 3, 1, p. 66-73 8 p.

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10 Citations (Scopus)

3 Downloads (Pure)

The relation between total cerebral small vessel disease burden and gait impairment in patients with minor stroke

Loos, C. M., McHutchison, C., Cvoro, V., Makin, S. D., Staals, J., Chappell, F., Dennis, M. S., van Oostenbrugge, R. J. & Wardlaw, J. M., 2018, In: International Journal of Stroke. 13, 5, p. 518-524 7 p.

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Open Access

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22 Citations (Scopus)

10 Downloads (Pure)

2017

Small Vessel Disease and Dietary Salt Intake: Cross-Sectional Study and Systematic Review

Makin, S. D. J., Mubki, G. F., Doubal, F. N., Shuler, K., Staals, J., Dennis, M. S. & Wardlaw, J. M., 31 Dec 2017, In: Journal of Stroke and Cerebrovascular Diseases. 26, 12, p. 3020-3028 9 p.

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27 Citations (Scopus)

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White matter hyperintensity reduction and outcomes after minor stroke

Wardlaw, J. M., Chappell, F. M., Valdes Hernandez, M. D. C., Makin, S. D. J., Staals, J., Shuler, K., Thrippleton, M. J., Armitage, P. A., Munoz-Maniega, S., Heye, A. K., Sakka, E. & Dennis, M. S., 5 Sept 2017, In: Neurology. 89, 10, p. 1003-1010 8 p.

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102 Citations (Scopus)

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Application of Texture Analysis to Study Small Vessel Disease and Blood-Brain Barrier Integrity

Valdes Hernandez, M. D. C., Gonzalez-Castro, V., Chappell, F. M., Sakka, E., Makin, S., Armitage, P. A., Nailon, W. H. & Wardlaw, J. M., 19 Jul 2017, In: Frontiers in Neurology. 8, 16 p., 327.

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25 Citations (Scopus)

8 Downloads (Pure)

Reliability of an automatic classifier for brain enlarged perivascular spaces burden and comparison with human performance

Gonzalez-Castro, V., Valdes Hernandez, M. D. C., Chappell, F. M., Armitage, P. A., Makin, S. & Wardlaw, J. M., Jul 2017, In: Clinical Science. 131, 13, p. 1465-1481 17 p.

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24 Citations (Scopus)

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Blood-brain barrier failure as a core mechanism in cerebral small vessel disease and dementia: evidence from a cohort study

Wardlaw, J. M., Makin, S. J., Valdés Hernández, M. C., Armitage, P. A., Heye, A. K., Chappell, F. M., Muñoz-Maniega, S., Sakka, E., Shuler, K., Dennis, M. S. & Thrippleton, M. J., 1 Jun 2017, In: Alzheimer's and Dementia. 13, 6, p. 634-643 10 p.

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173 Citations (Scopus)

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Sample size considerations for trials using cerebral white matter hyperintensity progression as an intermediate outcome at 1 year after mild stroke: results of a prospective cohort study

Chappell, F. M., Valdes Hernandez, M. D. C., Makin, S. D., Shuler, K., Sakka, E., Dennis, M. S., Armitage, P. A., Munoz Maniega, S. & Wardlaw, J. M., 21 Feb 2017, In: Trials. 18, 10 p., 78.

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15 Citations (Scopus)

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Integrity of normal-appearing white matter: Influence of age, visible lesion burden and hypertension in patients with small-vessel disease

Munoz Maniega, S., Chappell, F. M., Valdes Hernandez, M. C., Armitage, P. A., Makin, S. D., Heye, A. K., Thrippleton, M. J., Sakka, E., Shuler, K., Dennis, M. S. & Wardlaw, J. M., 1 Feb 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 2, p. 644-656 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

124 Citations (Scopus)

STROKOG (stroke and cognition consortium): An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease

Sachdev, P. S., Lo, J. W., Crawford, J. D., Mellon, L., Hickey, A., Williams, D., Bordet, R., Mendyk, A-M., Gele, P., Deplanque, D., Bae, H-J., Lim, J-S., Brodtmann, A., Werden, E., Cumming, T., Kohler, S., Verhey, F. R. J., Dong, Y-H., Tan, H. H., Chen, C., & 47 othersXin, X., Kalaria, R. N., Allan, L. M., Akinyemi, R. O., Ogunniyi, A., Klimkowicz-Mrowiec, A., Dichgans, M., Wollenweber, F. A., Zietemann, V., Hoffmann, M., Desmond, D. W., Linden, T., Blomstrand, C., Fagerberg, B., Skoog, I., Godefroy, O., Barbay, M., Roussel, M., Lee, B-C., Yu, K-H., Wardlaw, J., Makin, S. J., Doubal, F. N., Chappell, F. M., Srikanth, V. K., Thrift, A. G., Donnan, G. A., Kandiah, N., Chander, R. J., Lin, X., Cordonnier, C., Moulin, S., Rossi, C., Sabayan, B., Stott, D. J., Jukema, J. W., Melkas, S., Jokinen, H., Erkinjuntti, T., Mok, V. C. T., Wong, A., Lam, B. Y. K., Leys, D., Henon, H., Bombois, S., Lipnicki, D. M. & Kochan, N. A., 2017, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 7, p. 11-23 13 p.

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47 Citations (Scopus)

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2016

Cerebral blood flow in small vessel disease: A systematic review and meta-analysis

Shi, Y., Thrippleton, M. J., Makin, S. D., Marshall, I., Geerlings, M. I., de Craen, A. J., van Buchem, M. A. & Wardlaw, J. M., 1 Oct 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 10, p. 1653-1667 15 p.

Research output: Contribution to journal › Article › peer-review

215 Citations (Scopus)

Response to Letter Regarding Article, "Clinically Confirmed Stroke With Negative Diffusion-Weighted Imaging Magnetic Resonance Imaging: Longitudinal Study of Clinical Outcomes, Stroke Recurrence, and Systematic Review"

Makin, S. D. & Wardlaw, J. M., Mar 2016, In: Stroke. 47, 3, p. e54 1 p.

Research output: Contribution to journal › Article

Open Access

Stephen Makin

Research output

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